Results 71 to 80 of about 713,586 (294)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Research on a strongly generalizable fault diagnosis method based on adversarial transfer learning
Frontiers in Nuclear EngineeringIntroductionShallow machine learning algorithms exhibit low efficiency in fault diagnosis under the conditions of small-sample and unlabeled data. To address this critical problem, this paper focuses on developing an effective fault diagnosis method ...
Biwei Zhu +4 more
doaj +1 more source
Ethical issues of human cloning
Journal of Medical Sciences, 2020 Cloning can help us in the research field and medical sciences. But due to ethical and moral values, this idea is not supported. Moreover, it is against ethical values as well.
Nasrullah +5 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Data transfers for nuclear reactor multiphysics studies using the MOOSE framework
Frontiers in Nuclear EngineeringHigh fidelity simulations of nuclear systems generally require a multi-dimensional representation of the system. Advanced nuclear reactor cores are governed by multiple physical phenomena which should be all be resolved, and the coupling of these physics
Guillaume L. Giudicelli +11 more
doaj +1 more source
Biotechnological bases of the development of cloned pig embryos
Вавиловский журнал генетики и селекции, 2019 The term ‘clone’ in animal biotechnology refers to an organism derived from non-sexual reproduction, which is both a direct offspring and a genetic copy of the parent organism.
A. V. Lopukhov +2 more
doaj +1 more source
Advances in equine cloning by somatic cell nuclear transfer (SCNT) technique in horses: a review
International Journal of Bioassays, 2016 Cloning a horse means using the genetic material (DNA) from a donor horse to produce a genetically identical foal. This technique involves collecting the DNA from the donor and inserting that DNA into an egg from another mare whose, DNA content has been removed, fusing donor nucleus with enucleated recipient oocytes, which then develops as an embryo ...
Rajesh Wakchaure, Subha Ganguly*
openaire +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Morphological and Molecular Basis of Cytoplasmic Dilation and Swelling in Cortical Migrating Neurons
Brain Sciences, 2017 During corticogenesis, neuronal migration is an essential step for formation of a functional brain, and abnormal migration is known to cause various neurological disorders.
Yoshiaki V. Nishimura +2 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source