Results 251 to 260 of about 3,924,444 (330)

The Mechanism of Ran Import into the Nucleus by Nuclear Transport Factor 2 [PDF]

, 2000
Brooks Quimby, Todd Lamitina, Steven W. L’Hernault, Anita H. Corbett   +3 more
openalex   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Competitive Binding of Viral Nuclear Localization Signal Peptide and Inhibitor Ligands to Importin-α Nuclear Transport Protein. [PDF]

J Chem Inf Model
Delfing BM, Laracuente XE, Jeffries W, Luo X, Olson A, Foreman KW, Petruncio G, Lee KH, Paige M, Kehn-Hall K, Lockhart C, Klimov DK.   +11 more
europepmc   +1 more source

Ivermectin effectively inhibits hepatitis E virus replication, requiring the host nuclear transport protein importin α1. [PDF]

Arch Virol, 2021
Li Y, Miao Z, Li P, Zhang R, Kainov DE, Ma Z, de Man RA, Peppelenbosch MP, Pan Q.   +8 more
europepmc   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Beyond microtubules: The cellular environment at the endoplasmic reticulum attracts proteins to the nucleus, enabling nuclear transport. [PDF]

iScience
Chae SJ, Kim DW, Igoshin OA, Lee S, Kim JK.   +4 more
europepmc   +1 more source

Nuclear Transport of the Major Capsid Protein Is Essential for Adeno-Associated Virus Capsid Formation

, 1999
Mainul Hoque, Kenichiro Ishizu, Akiko Matsumoto, Song‐iee Han, Fumio Arisaka, Makoto Takayama, Kenji Suzuki, Kenzo KATO, Tadahito Kanda, Hajime Watanabe, Hiroshi Handa   +10 more
openalex   +1 more source

Nuclear Export of Map Kinase (ERK) Involves a Map Kinase Kinase (Mek-Dependent) Active Transport Mechanism [PDF]

, 2000
Makoto Adachi, Makoto Fukuda, Eisuke Nishida   +2 more
openalex   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Nuclear Transport of Epstein-Barr Virus DNA Polymerase Is Dependent on the BMRF1 Polymerase Processivity Factor and Molecular Chaperone Hsp90

Journal of Virology, 2013
D. Kawashima, T. Kanda, T. Murata, Shinichi Saito, A. Sugimoto, Yohei Narita, T. Tsurumi   +6 more
semanticscholar   +1 more source