Results 91 to 100 of about 788,142 (267)

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Electrochemically Driven Dissipative Growth of Affinity Hydrogels for Bioresponsive Interfaces

Advanced Functional Materials, EarlyView.
Voltage pulses drive the growth and reinforcement of hydrogel films under dissipative conditions. This biocompatible strategy enables efficient integration of affinity ligands into the hydrogel matrix, enhancing the selective capture of growth factors and allowing precise temporal control over their release, making them well‐suited as adaptive ...
Roberto Baretta, Marco Frasconi
wiley   +1 more source

Beginning of a new era of synthetic messenger RNA therapeutics: Comprehensive insights on mRNA drug design, development and applications

Experimental Biology and Medicine
Messenger RNA (mRNA) therapeutics have significantly transformed contemporary medicine, particularly through their role as the active component in the SARS-CoV-2 vaccine. This remarkable achievement is the culmination of extensive research conducted over
Saumya Nishanga Heendeniya, Saumya Nishanga Heendeniya, Suxiang Chen, Suxiang Chen, Saadia Bhatti, Saadia Bhatti, Qurat Ul Ain Zahra, Kamal Rahimizadeh, Bal Hari Poudel, Bal Hari Poudel, Stephen D. Wilton, Stephen D. Wilton, Rakesh N. Veedu, Rakesh N. Veedu   +13 more
doaj   +1 more source

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

Berberine, a Natural Compound That Demonstrates Antiviral Effects Against Ostreid Herpesvirus 1 Infection in Anadara broughtonii

Viruses
Ostreid herpesvirus 1 (OsHV-1) infection is the primary viral disease responsible for large-scale mortality in bivalve mollusks worldwide, and effective strategies to control the outbreaks of this disease are still lacking.
Hui-Gang Kang, Mao-Le Wei, Jing-Li Wang, Cui-Ping Ma, Xiang Zhang, Bo-Wen Huang, Lu-Sheng Xin, Chang-Ming Bai   +7 more
doaj   +1 more source

Detection of feline immunodeficiency virus (FIV) nucleic acids in FIV-seronegative cats [PDF]

, 1992
Satya Dandekar, Amy M. Beebe, J E Barlough, T R Phillips, John H. Elder, M Torten, Niels C. Pedersen   +6 more
openalex   +1 more source

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source

An antioxidant nanozyme for targeted cardiac fibrosis therapy post myocardial infarction

Journal of Nanobiotechnology
The excessive release of reactive oxygen species (ROS) after myocardial infarction (MI) disrupts the natural healing process, leading to cardiac fibrosis and compromising patient prognosis.
Ziyi Gu, Xueliang Liu, Zhen Qi, Zhou Fang, Yiting Jiang, Yuting Huang, Yongyi Wang, Lianming Wu, Yu Yang   +8 more
doaj   +1 more source

Development and formation of wing cuticle based on transcriptomic analysis in Locusta migratoria during metamorphosis

Journal of Integrative Agriculture
Wings are an important flight organ of insects. Wing development is a complex process controlled by a series of genes. The flightless wing pad transforms into a mature wing with the function of migratory flight during the nymph-to-adult metamorphosis ...
Jing Zhang, Zhaochen Wu, Shuo Li, He Huang, Suning Liu, Weimin Liu, Xiaoming Zhao, Jianzhen Zhang   +7 more
doaj   +1 more source

High‐Resolution Characterization of Protein‐Conjugated, mRNA‐Loaded Lipid Nanoparticles by Analytical Ultracentrifugation

Advanced Functional Materials, EarlyView.
Lipid nanoparticles containing messenger RNA are characterized by sedimentation velocity analytical ultracentrifugation using UltraScan's new Custom Grid algorithm to provide multi‐dimensional distributions for partial specific volume (particle density), molar mass, sedimentation, diffusion, and hydrodynamic radius.
Sophia Bird, Connor Smith, Nahal Habibi, Samantha Rivera, Saeed Mortezazadeh, Reece Martin, Benjamin M. Geilich, Gilles Besin, Borries Demeler   +8 more
wiley   +1 more source