CRISPR-Cas12a-assisted nucleic acid detection
Cell Discovery, 2018 Dear Editor, Today, the need for time-effective and cost-effective nucleic acid detection methods is still growing in fields such as human genotyping and pathogen detection.
Shiyuan Li +8 more
semanticscholar +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Fast and sensitive determination of camel's and goat's meat and milk using species-specific genetic markers [PDF]
Biotechnology in Animal Husbandry, 2015 For the fast and sensitive determination of camel's and goat's meat and milk, species-specific regions (SSR) of follicle stimulating hormone receptor (FSHR) gene in both camel and goat were amplified using PCR technique.
Abdel-Rahman S.M. +2 more
doaj
Chemical reaction-mediated covalent localization of bacteria
Nature Communications, 2022 Transplantation of helpful bacteria has been used to treat disease through modulating host microbiota. Here, the authors report a strategy to control bacteria localization in the jejunum, via an in vivo in-situ thiol-disulfide exchange reaction between ...
Huilong Luo +9 more
doaj +1 more source
Use of streptavidin bound to biotinylated DNA structures as model substrates for analysis of nucleoprotein complex disruption by helicases [PDF]
, 2016 Helicases are a subfamily of translocases that couple the directional translocation along a nucleic acid lattice to the separation of nucleic acid duplexes using the energy derived from nucleoside triphosphate hydrolysis.
Brüning, Jan-Gert +2 more
core +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Metode Nucleic Acid Test Untuk Uji Saring Virus Hepatitis B Pada Darah Donor Dengan Hepatitis B Occult [PDF]
, 2015 HBsAg is the primary screening at the Blood Transfusion Unit (UTD) in Indonesia. Blood with HBsAg negative still have potential to transmit the Hepatitis B Virus (HBV) infection.
Setiawaty, V. (Vivi) +1 more
core
Self-partitioning SlipChip for slip-induced droplet formation and human papillomavirus viral load quantification with digital LAMP [PDF]
, 2020 Human papillomavirus (HPV) is one of the most common sexually transmitted infections worldwide, and persistent HPV infection can cause warts and even cancer.
Han, Xu +8 more
core
HiTRACE: High-throughput robust analysis for capillary electrophoresis [PDF]
, 2011 Motivation: Capillary electrophoresis (CE) of nucleic acids is a workhorse technology underlying high-throughput genome analysis and large-scale chemical mapping for nucleic acid structural inference. Despite the wide availability of CE-based instruments,
Bylund +39 more
core +1 more source
Nucleic Acids Research, 2002 We describe a new method for relative quantification of 40 different DNA sequences in an easy to perform reaction requiring only 20 ng of human DNA. Applications shown of this multiplex ligation-dependent probe amplification (MLPA) technique include the ...
J. Schouten +5 more
semanticscholar +1 more source