Results 91 to 100 of about 202,030 (205)

Synchrotron-radiation vacuum-ultraviolet circular dichroism spectroscopy in structural biology: an overview

Biophysics and Physicobiology, 2019
Circular dichroism spectroscopy is widely used for analyzing the structures of chiral molecules, including biomolecules. Vacuum-ultraviolet circular dichroism (VUVCD) spectroscopy using synchrotron radiation can extend the short-wavelength limit into the
Kunihiko Gekko
doaj   +1 more source

Nucleic Acid Conformation Influences Postsynthetic Suzuki-Miyaura Labeling of Oligonucleotides. [PDF]

Bioconjug Chem, 2020
Walunj MB, Srivatsan SG.
europepmc   +1 more source

Buffer optimization of siRNA-lipid nanoparticles mitigates lipid oxidation and RNA-lipid adduct formation

Nature Communications
Lipid nanoparticles are a versatile class of clinically approved drug delivery vehicles, particularly for nucleic acid cargoes. Despite this, these materials often suffer from instability issues that limit shelf-life or necessitate storage at ultra-cold ...
Daniel A. Estabrook, Lihua Huang, Olivia R. Lucchese, Dylan J. Charland, Zhao Yu, Fareed Bhasha Sayyed, Jonas Y. Buser, Younghoon Oh, Xingyan Liu, Harmon A. Johnson, Kenneth G. Rodriguez, Noah A. Wambolt, Sonia A. Corba, Geoffrey T. Nash, Dennis Yang, Tingting Wang   +15 more
doaj   +1 more source

Analysis of conformational parameters in nucleic acid fragments. II. Co-crystal complexes of nucleic acid bases

Nucleic Acids Research, 1988
Studies have been made of conformational parameters in co-crystal complexes and compounds of nucleic acid bases in which there is the possibility of formation of hetero-base-pairs. Using published data extracted from the Cambridge structural database, a total of 37 base-pairs were found, of which 25 were hetero-pairs and 12 homo-pairs. These base-pairs
openaire   +3 more sources

Nucleic Acid Reactivity and Conformation

Journal of Biological Chemistry, 1973
Robert Shapiro, Barbara Braverman, Judith B. Louis, Robert E. Servis   +3 more
openaire   +1 more source

Protein-DNA complexation: contact profiles in DNA grooves

Біофізичний вісник, 2017
Background: Investigation of the specific protein-DNA complexation mechanisms allows to establish general principles of molecular recognition, which must be taken into account while developing artificial nanostructures based on DNA, and to improve the ...
M. Yu. Zhitnikova, A. V. Shestopalova
doaj  

Mesoscopic irreversible thermodynamics of aging kinetics of alpha polypeptides [DNA] under various constraints: Special reference to the simple spring mechanics

AIP Advances
The mesoscopic irreversible thermodynamic treatment of α-polypeptides and the helical polynucleotides (DNA) furnishes two sets of analytical expressions, which allow us not only to analyze the reversible force–extension experiments performed by atomic ...
Tarik Omer Ogurtani
doaj   +1 more source

The structural basis of differential DNA sequence recognition by restriction–modification controller proteins [PDF]

, 2012
Ball, Neil J., Kneale, Geoff, McGeehan, John, Streeter, Simon, Thresh, Sarah   +4 more
core   +1 more source

Bacteriophage T4 gene 32 protein: Insights into its interaction with ssDNA, binding cooperativity, and conformational change. [PDF]

PLoS One
Guei J, Chapman MP, Brothers PN, Desai S, Karpel RL.   +4 more
europepmc   +1 more source

New targets and procedures for validating the valence geometry of nucleic acid structures. [PDF]

Nucleic Acids Res
Černý J, Nicholls RA, Brzezinski D, Berman HM, Gilski M, Joosten RP, Kowiel M, Lawson CL, Moriarty NW, Richardson JS, Schneider B, Vonrhein C, Williams CJ, Jaskólski M, Egli M.   +14 more
europepmc   +1 more source