Results 131 to 140 of about 194,899 (239)

Direct Modeling of DNA and RNA Aptamers with AlphaFold 3: A Promising Tool for Predicting Aptamer Structures and Aptamer-Target Interactions. [PDF]

ACS Synth Biol
Ochoa S, Milam VT.
europepmc   +1 more source

Nanostructured Protein Surfaces Inspired by Spider Silk

Advanced Materials, EarlyView.
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley   +1 more source

Chirality-Promoted Chemical Ligation and Reverse Transcription of <i>Acyclic</i> Threoninol Nucleic Acid. [PDF]

J Am Chem Soc
Okita H, Murayama K, Asanuma H.
europepmc   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

Predicting rare DNA conformations via dynamical graphical models: a case study of the B→A transition. [PDF]

Nucleic Acids Res
De Silva N, Perez A.
europepmc   +1 more source

Biomolecular Condensates as Emerging Biomaterials: Functional Mechanisms and Advances in Computational and Experimental Approaches

Advanced Materials, EarlyView.
Integration of computational and experimental approaches for deciphering the underlying mechanism of biomolecular condensates and potential biomaterials design (Created in Biorender. Raza, Z. (2025) https://BioRender.com/irgmeqi). Abstract Biomolecular condensates, a ubiquitous class of biomaterials found in living cells, have been shown to be ...
Qiang Zhu, Zahra Raza, Dzung Do‐Ha, Emma De Costa, Pavlina Sasheva, Luke McAlary, Hadi Mahmodi, Warwick P. Bowen, Lezanne Ooi, Irina Kabakova, Haibo Yu   +10 more
wiley   +1 more source

Structural flexibility in the ordered domain of the dengue virus strain 2 capsid protein is critical for chaperoning viral RNA replication. [PDF]

Cell Mol Life Sci
Sharma KK, Raghuvamsi PV, Aik DYK, Marzinek JK, Bond PJ, Wohland T.   +5 more
europepmc   +1 more source

Artificial Intelligence‐Driven Nanoarchitectonics for Smart Targeted Drug Delivery

Advanced Materials, EarlyView.
This perspective introduces an artificial intelligence (AI)‐driven nanoarchitectonics framework for targeted drug delivery, combining database‐guided nanocarrier design, machine learning (ML)‐assisted surface engineering with a designed targeting system, and in silico modeling for dynamic optimization.
Hayeon Bae, Hyunsub Ji, Konstantin Konstantinov, Ronald Sluyter, Katsuhiko Ariga, Yong Ho Kim, Jung Ho Kim   +6 more
wiley   +1 more source

Molecular dynamics as an approach to study prion protein misfolding and the effect of pathogenic mutations [PDF]

, 2011
Daggett, Valerie, van der Kamp, Marc W
core   +1 more source

Supersecondary Structure Code for RNA: Trace of Conformational Change on the Mycoplasma pneumoniae Ribosome and the R-Loop Formation of Cas9. [PDF]

ACS Omega
Izumi H, Nafie LA, Dukor RK.
europepmc   +1 more source