Results 171 to 180 of about 438,619 (385)
Protein-DNA complexation: contact profiles in DNA grooves
Background: Investigation of the specific protein-DNA complexation mechanisms allows to establish general principles of molecular recognition, which must be taken into account while developing artificial nanostructures based on DNA, and to improve the ...
M. Yu. Zhitnikova, A. V. Shestopalova
doaj
Solution structures of DEAD-box RNA chaperones reveal conformational changes and nucleic acid tethering by a basic tail [PDF]
Anna L. Mallam+7 more
openalex +1 more source
This study provides a deeper exploration into the surface interactions of interstitial fluid (ISF) and polymeric hollow microneedle (HMN) surfaces by investigating the effects of fabrication‐induced surface changes on the microchannels of 3 different polymeric HMNs.
Ipek Atay+6 more
wiley +1 more source
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao+6 more
wiley +1 more source
Synthesis of Artificial Nucleic Acids Functionalized by Fixation of Conformation.
Mitsuo Sekine
openalex +2 more sources
The phosphate clamp: sequence selective nucleic acid binding profiles and conformational induction of endonuclease inhibition by cationic Triplatin complexes [PDF]
Andreea Prisecaru+6 more
openalex +1 more source
Electrospinning enables the hierarchical assembly of nanofiber‐based scaffolds for tissue engineering. However, encapsulated proteins often undergo structural changes. This study used mesoporous silica nanoparticles (MSNs) as protective carriers, mitigating protein denaturation and supporting controlled release.
Vera Citro+5 more
wiley +1 more source
The mesoscopic irreversible thermodynamic treatment of α-polypeptides and the helical polynucleotides (DNA) furnishes two sets of analytical expressions, which allow us not only to analyze the reversible force–extension experiments performed by atomic ...
Tarik Omer Ogurtani
doaj +1 more source