Results 171 to 180 of about 202,030 (205)

Theoretical Probes of Nucleic Acid Conformation

1983
The computations described briefly here illustrate the interrelationship between the local structure and macroscopic behavior of the DNA helix. Statistical mechanical studies help to identify the most likely morphological arrangements of the polynucleotide backbone and to understand the macroscopic flexibility of the DNA as a whole.
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Nucleic acid analogs: Conformation and their functionalities

Die Makromolekulare Chemie, 1985
Poly-L-, -D-, and -DL-lysine derivatives having pendant nucleic acid bases were prepared by using a polymer modification reaction. Conformation of the polymers was studied by CD and ORD measurements, and the effects of pH of the system, as well as the solvents on the helicity of the polymers were investigated in detail.
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Evolution of conformational principles in nucleic acids

International Journal of Quantum Chemistry, 2009
The analysis of conformations of nucleic acids and polynucleotides have been greatly simplified by the important observations that the nucleotide building blocks exhibit two classes of preferred conformations and that the flexibility in the polynucleotide chain resides mainly in the internucleotide PO linkages.
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Magnesium-nucleic acid conformational changes and cancer.

Magnesium, 1987
The magnesium interaction with the mononucleotide guanosine-5'-monophosphate disodium salt (5'-GMP Na2 or G5'p) has been studied by Fourier transform infrared spectroscopy. The results have been compared with previously obtained proton nuclear magnetic data on the same system as well as other similar systems.
T, Theophanides, M, Polissiou
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A conformation-specific chemical modification of nucleic acids

Biochemical Pharmacology, 1988
P, Roques, M, Olomucki
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Nucleic Acids: Conformation Contorted

Nature, 1973
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PROTON MAGNETIC RESONANCE STUDIES OF NUCLEIC ACID CONFORMATION *

Annals of the New York Academy of Sciences, 1973
P O, Ts'o, J C, Barrett, L S, Kan, P S, Miller   +3 more
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Tumour fatty acid metabolism in the context of therapy resistance and obesity

Nature Reviews Cancer, 2021
Andrew J Hoy, Shilpa R Nagarajan, Lisa M Butler   +2 more
exaly  

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

Cancer Cell, 2022
Kota Itahashi, Yosuke Togashi, Takahiro Kamada   +2 more
exaly  

Furanose ring conformation in nucleosides and nucleic acids

Journal of Molecular Biology, 1969
H R, Wilson, A, Rahman, P, Tollin
openaire   +2 more sources