Results 171 to 180 of about 205,585 (348)

DNA Origami‐Templated Aptamer Chiral Structures Realize Cellular Enantioselectivity

Advanced Materials, EarlyView.
Aptamers displayed on tubular DNA origami nanostructures in defined chiral orientations (left‐ or right‐handed) exhibit enantioselective interactions with cell surface target proteins. While the right‐handed configuration supports only transient binding, the left handedness energetically favors protein dimerization and promotes subsequent ...
Tingjie Song, Abhisek Dwivedy, Dhanush Gandavadi, Gayatri Chandran, Yiquan An, Mengxi Zheng, Xiaojing Wang, Lifeng Zhou, Yang Zhao, Xing Wang   +9 more
wiley   +1 more source

Conformationally restricted cationic polyamide analogs of nucleic acids: Design, synthesis, and DNA/RNA binding studies [PDF]

, 2004
Vaijayanti A. Kumar, Moneesha D’Costa, Pallavi Lonkar, Meena Meena, Pradeep S. Pallan, Krishna N. Ganesh   +5 more
openalex   +1 more source

Two‐Photon 3D Printing of Functional Microstructures Inside Living Cells

Advanced Materials, EarlyView.
This study demonstrates 3D printing inside living cells by using two‐photon photo‐lithography. A bio‐compatible photoresist is injected into cells and selectively polymerized with a femtosecond laser, creating custom‐shaped intracellular structures with submicron resolution.
Maruša Mur, Aljaž Kavčič, Uroš Jagodič, Rok Podlipec, Matjaž Humar   +4 more
wiley   +1 more source

Vibrational analysis of nucleic acids. V. Force field and conformation-dependent modes of the phosphodiester backbone modeled by diethyl phosphate

, 1996
Yifu Guan, G.J. Thomas
openalex   +1 more source

Materials and System Design for Self‐Decision Bioelectronic Systems

Advanced Materials, EarlyView.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng, Hong Liu, Yongheng Zhang, Youbin Zheng, Xuyin Ding, Mengni Zhu, Guoyue Shi, Yan Wang, Hossam Haick, Min Zhang   +9 more
wiley   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

New targets and procedures for validating the valence geometry of nucleic acid structures. [PDF]

Nucleic Acids Res
Černý J, Nicholls RA, Brzezinski D, Berman HM, Gilski M, Joosten RP, Kowiel M, Lawson CL, Moriarty NW, Richardson JS, Schneider B, Vonrhein C, Williams CJ, Jaskólski M, Egli M.   +14 more
europepmc   +1 more source

Membrane Semi‐Permeability and Ion Selectivity in Chemiosmosis: Open Systems Volume Dependence of Electrolyte Chemistry

Advanced Materials Interfaces, EarlyView.
Very small cellular compartments can break electroneutrality and harness proton gradients without active transport structures, whereas larger volumes cannot, underscoring why life's critical energy processes are confined in microscopic spaces. ABSTRACT The effect of pH changes in external ionic solutions on liposomes entrapping non‐permeable weak acid ...
Josep M. Ribó, Isabel Herreros, David Hochberg, Federico Morán, Michael Stich   +4 more
wiley   +1 more source

Structural analysis of uridine modifications in solved RNA structures. [PDF]

NAR Genom Bioinform
Arteaga SJ, Znosko BM.
europepmc   +1 more source

Electron Correlated Ab Initio Study of Amino Group Flexibility for Improvement of Molecular Mechanics Simulations on Nucleic Acid Conformations and Interactions [PDF]

, 2007
V. I. Poltev, Edwin J. González López, A. Deriabina, Anna Victoria Martinez, Al’ona Furmanchuk, Leonid Gorb, Jerzy Leszczyński   +6 more
openalex   +1 more source