Results 221 to 230 of about 194,899 (239)

Conformational Flexibility of Nucleic Acids

1983
In consideration of the importance of conformational flexibility to the functioning of nucleic acids, NMR studies have been carried out to elucidate aspects of dynamics with molecular Mechanics calculations providing supplementary insight. Analysis of 31P and 13C NMR relaxation data in terms of plausible motions in a DNA helix indicate that winding and
Peter Bendel, Joe W. Keepers, Joseph Murphy-Boesch, Peter A. Kollman, Jacqueline L. James, John Taylor, Aviva Lapidot, Thomas L. James   +7 more
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Conformational properties of nucleic acids in solution

International Journal of Quantum Chemistry, 2009
Principles which govern the conformational properties of nucleic acid structures in aqueous solution are derived from extensive nuclear magnetic resonance studies of nucleic acid components. These principles are then utilized to project the solution conformation of tRNA.
Ramaswamy H. Sarma, Steven S. Danyluk
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Forces involved in the Conformational Stability of Nucleic Acids

Nature, 1969
ONE of the most important problems in research on nucleic acid is the understanding of the forces which maintain the helical structure. After the elucidation of the double helix by Watson and Crick1, the helical secondary structure of DNA was thought to derive its stability from hydrogen bonding between the base pair. The discovery that polynucleotides
J. Brahms, Fritz Eckstein, J. C. Maurizot   +2 more
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Nucleic acid analogs: Conformation and their functionalities

Die Makromolekulare Chemie, 1985
Poly-L-, -D-, and -DL-lysine derivatives having pendant nucleic acid bases were prepared by using a polymer modification reaction. Conformation of the polymers was studied by CD and ORD measurements, and the effects of pH of the system, as well as the solvents on the helicity of the polymers were investigated in detail.
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Single molecule approaches of nucleic acids conformational changes

Methods, 2019
Single molecule approaches of nucleic acids conformational changes One of the primordial questions today in biology is: how does DNA regulate its own metabolism? In other words, what are the mechanisms that enables specific genes to be transcribed while others are silenced?
Lavelle, Christophe, Tardin, Catherine
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Evolution of conformational principles in nucleic acids

International Journal of Quantum Chemistry, 2009
The analysis of conformations of nucleic acids and polynucleotides have been greatly simplified by the important observations that the nucleotide building blocks exhibit two classes of preferred conformations and that the flexibility in the polynucleotide chain resides mainly in the internucleotide PO linkages.
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Infrared Studies on the Backbone Conformation of Nucleic Acids

Israel Journal of Chemistry, 1974
AbstractThe presence and assignment of low frequency infrared bands characteristic of the A, B and C forms of DNA (Salmon Sperm and Micrococcus Lysodeikticus) and of synthetic poly (dA‐T): (dA‐T) and of polyribonucleotides‐A form are considered. The vibrational modes that may arise from the phosphate diester stretch of DNA backbone are investigated in ...
J. Brahms, S. Brahms, J. Pilet
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Conformation of Viral Nucleic Acids in Situ

1969
Publisher Summary The problems that are discussed in this chapter are confined to viruses, and to be more exact, to the question of similarities and differences between the structure and properties of usual forms of nucleic acids in solution and that of nucleic acids inside viral particles.
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Conformational principles of nucleic acids

1981
From a conformational standpoint, nucleic acids are enormously complex. In order to rigorously describe, for example, the secondary structure of a repeating polynucleotide such as fibrous poly dA·dT, the values of twelve torsion angles must be ascertained (Figure 1.1); contrast this with a repeating polypeptide where only two conformation angles need ...
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Structure and Conformation of Nucleic Acids and Protein-Nucleic Acid Interactions [PDF]

Biochemical Society Transactions, 1976
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