Results 21 to 30 of about 2,997,790 (301)
Crystal structure of a DNA containing the planar, phenoxazine-derived bi-functional spectroscopic probe Ç [PDF]
, 2011 Electron Paramagnetic Resonance (EPR) spectroscopy and fluorescence spectroscopy are complementary biophysical techniques used to examine the structure and dynamics of macromolecules.
Reginsson, Gunnar Widtfeldt +13 more
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Protein-DNA interactions: statistical analysis of interatomic contacts in major and minor grooves
Вавиловский журнал генетики и селекции, 2018 The interactions between protein and DNA in essence underlie all processes in a living cell. Understanding the principles of specific recognition of DNA sites will open the way to understand how these processes are controlled and to interfere in their ...
A. A. Anashkina +5 more
doaj +1 more source
Quantification bias caused by plasmid DNA conformation in quantitative real-time PCR assay. [PDF]
PLoS ONE, 2011 Quantitative real-time PCR (qPCR) is the gold standard for the quantification of specific nucleic acid sequences. However, a serious concern has been revealed in a recent report: supercoiled plasmid standards cause significant over-estimation in qPCR ...
Chih-Hui Lin +2 more
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Conformational classification of functional nucleic acids [PDF]
Nucleic Acids Symposium Series, 1999 The kink parameters would provide the tolerant aspect for irregular helical structure of nucleic acid. Using these kink parameters, the classification of conformation space was carried for the functional nucleic acid molecules. The kink parameters could afford us the simple structural aspects about the constructive parts of functional molecules.
openaire +2 more sources
Solvent interactions stabilising nucleic acid conformers [PDF]
Nucleic Acids Research, 1989 The transition of oligonucleotides from the B to the A conformation has been studied by the use of simple geometric calculations aimed at finding possible hydration sites which could stabilize these conformations. The method involves the classification of equally spaced grid points, surrounding the oligonucleotide, into groups depending on whether a ...
R J, Elliott, J M, Goodfellow
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Novel Selenium-modified Nucleic Acids For Structural and Functional Studies [PDF]
, 2015 Nucleic acids, as one of the most important macromolecules in living systems, play critical roles in storing, transferring, regulating genetic information, directing proteins synthesis, and catalysis. Understanding the structure of nucleic acid can bring
Jiang, Sibo
core +1 more source
New Journal of Physics, 2013 We have observed the conformation-dependent electronic coupling between the monomeric subunits of a dinucleotide of 2-aminopurine (2-AP), a fluorescent analogue of the nucleic acid base adenine.
Julia R Widom +3 more
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The conformation of single‐stranded nucleic acids [PDF]
European Journal of Biochemistry, 1990 Conformational analyses using the single‐strand‐specific nuclease from mung bean and restriction endonucleases have been performed on a series of DNA fragments related to the sequence of the yeast initiator tRNAMet. Mung bean nuclease cleaves DNA fragments exclusively in some, but not all, single‐stranded regions as predicted by RNA secondary rules ...
J, Paquette +4 more
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Microgels and apparatus for PAGE of nucleic acids in one or two dimensions
BioTechniques, 2018 We describe a system for horizontal 1D or 2D PAGE comprising an apparatus and microgels. There is no buffer outside the gel, making handling and sample loading easy.
Hans G Thormar +5 more
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Insights on the DNA Stability in Aqueous Solutions of Ionic Liquids
Frontiers in Bioengineering and Biotechnology, 2020 Deoxyribonucleic acid (DNA) carries the genetic information essential for the growth and functioning of living organisms, playing a significant role in life sciences research.
Teresa B. V. Dinis +2 more
doaj +1 more source