Results 211 to 220 of about 67,253 (293)

Machine learning-directed massively parallel programmable nucleic acid amplification. [PDF]

Sci Adv
Weng Z, Huang W, Wu Y, Xiu X, Lv H, Wang F, Zuo X, Fan C, Song P.   +8 more
europepmc   +1 more source

A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection

Advanced Science, Volume 13, Issue 32, 9 June 2026.
A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Zeyu Wang, Jiahao Li, Zhuying Yue, Beixuan He, Wenhua Zhang, Zhen Fang, Qing Xia, Yingbin Liu, Yanjing Li   +8 more
wiley   +1 more source

Application of Raman Spectroscopy to Rapid Discrimination of Autochthonous Lactic Acid Bacteria Isolated from Goat Cheese. [PDF]

Curr Issues Mol Biol
Bustos AY, Carol Paz JJ, Gómez JN, Ledesma AE.   +3 more
europepmc   +1 more source

Multimodal Multiorgan‐on‐a‐Chip Platform for Probing Liver‐Tumor Interactions and Advancing Prodrug Screening

Advanced Science, Volume 13, Issue 34, 19 June 2026.
This work introduces a multimodal multi‐OoC platform that overcomes current limitations in liver‐tumor interaction studies and prodrug screening. By integrating dynamic microfluidic circuits, electrochemical sensing, and mass analysis, this platform enables non‐invasive, longitudinal monitoring of drug metabolism and hepatotoxicity, offering a ...
Dan Wang, Yisong Huang, Weijian Zhao, Tian Chen, Siyu Bai, Denghui Guo, Mengying Wang, Yaoyao Zhao, Liang Zhao, Guangsheng Guo, Xiayan Wang   +10 more
wiley   +1 more source

Multiplex One-Step qPCR/RT-qPCR Assays for Detection of Ectromelia Virus, Murine Hepatitis Virus, Reovirus Type 3, and Parvoviruses. [PDF]

Vet Sci
Luo W, Li X, Zhang Y, Chang J, Xu G.
europepmc   +1 more source

Combining ultrastructure expansion microscopy with immunofluorescence and Oligopaint DNA FISH. [PDF]

Chromosome Res
Raab LM, Hockens CB, Lee LS, Runyan RK, Burns EE, Rusan NM, Rosin LF.   +6 more
europepmc   +1 more source

Current and emerging molecular diagnostic approaches in the detection of human parasites. [PDF]

Parasitol Res
Pistone D, Bevivino G, Dipaola MG, Bandi C, Lombardo F.   +4 more
europepmc   +1 more source

High‐Yield Production and Cost‐Effective Purification of an Alkali‐Resistant Hexameric Protein A Variant for Antibody Affinity Chromatography

Biotechnology Journal, Volume 21, Issue 6, June 2026.
Graphical Abstract and Lay Summary We present a scalable method for producing the antibody‐binding ligand Z6AlkC, a six‐repeat, alkali‐resistant Protein A–derived Z domain with a terminal cysteine. The ligand was produced at high yield via extracellular secretion in bioreactors and subsequently purified by high‐productivity ultradiafiltration with low ...
Carolina Mota Natal, Claudia Lacombe, Alexander Zollner, Catarina Domingos, José Mendes, André Nascimento, Ana Margarida Gonçalves Carvalho Dias, Arménio Jorge Moura Barbosa, Cristina Peixoto, Birgit Wiltschi, Alois Jungbauer, Ana Cecília Afonso Roque   +11 more
wiley   +1 more source

Delivering Proteins and Enzymes to Solid Tumors Through the Development of Stimuli‐Responsive Nanocarriers

ChemNanoMat, Volume 12, Issue 6, June 2026.
Stimuli‐responsive strategies to achieve controlled release of protein‐based therapeutic agents into solid tumors. Proteins, enzymes, and peptides have long been recognized as valuable therapeutic agents, particularly in oncology. However, their complex chemical structures render them more sensitive than smaller chemotherapeutic drugs.
Guillermo Plaza‐Palomo, Diana Benita‐Donadios, Sandra Jiménez‐Falcao, Alejandro Baeza   +3 more
wiley   +1 more source

Lignin-Encapsulated ZnO Nano-Hybrids Exhibit Enhanced Antibacterial and Photocatalytic Activity via ROS-Mediated Oxidative Stress and Bacterial Membrane Disruption. [PDF]

ACS Omega
Samal P, Satpathy S, Rath G, Sabut T, Sahoo AP, Arakha M.   +5 more
europepmc   +1 more source