Results 201 to 210 of about 67,253 (293)

Differences and Similarities in Protein and Nucleic Acid Structures and Their Biological Interactions. [PDF]

Curr Issues Mol Biol
Arakawa T, Oyama T, Ura T, Nishinami S, Shiraki K, Akuta T.   +5 more
europepmc   +1 more source

In Vitro Biological Activities of Piper corcovadensis C.DC.: Antioxidant, Antineoplastic‐Related and Antibacterial Effects

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Piper corcovadensis extract is rich in bioactive compounds with antioxidant potential, capable of decreasing ROS levels; antitumor activity in cutaneous melanoma cells SK‐MEL‐28; and anti‐inflammatory activity, decreasing the expression of IL‐6 and NLPR3 genes and increasing TNF expression, without cytotoxicity to healthy peripheral blood cells (PBMCs).
Bruno Henrique Fontoura, Ellen Cristina Perin, Margarete Dulce Bagatini, Daiane Manica, Gilnei Bruno da Silva, Michelle Fernanda Faita Rodrigues, José Abramo Marchese, Solange Teresinha Carpes   +7 more
wiley   +1 more source

Uracil-Peptide-Pyrene Conjugates as Cu²⁺-Sensitive Probes Targeting DNA, RNA, and Biorelevant Model Membranes. [PDF]

Chembiochem
Pavlović Saftić D, Lulić Horvat L, Piantanida I.   +2 more
europepmc   +1 more source

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, Volume 38, Issue 33, 12 June 2026.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, Volume 11, Issue 12, 18 June 2026.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Efficient and specific DNA-targeting using single-stranded LNA/MOE mixmers and chimeric Invader:XenoRNA probes. [PDF]

Org Biomol Chem
Everly ME, Hrdlicka PJ.
europepmc   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

Development and clinical application of a rapid qPCR instrument featuring three independent temperature modules and a time-based algorithm for respiratory pathogen diagnosis. [PDF]

Virol J
Wang Y, Wang H, Zhou M, Wang M, Wu T, Zhou S, Liao X, Liu W, Zhuang X, Zhou Z, Zhou R.   +10 more
europepmc   +1 more source

Visualization of Endosomal Escape of Intracellularly Delivered Protein With Unexpected Photochemical Internalization of Trypan Blue

Advanced Science, Volume 13, Issue 32, 9 June 2026.
TB, a conventional cell viability dye, acts as both a fluorescence modulator (quenching GFP fluorescence upon protein binding and recovering it upon release) and a photosensitizer that triggers endosomal escape via photochemical internalization (PCI) under 590 nm light.
Zhongqi Yao, Zhan Shi, Peng Hu, Changping Wang, Hui Wang   +4 more
wiley   +1 more source

BNB/NBN‐Phenalenyl‐2'‐deoxyuridines as a Fluorophore–Quencher Pair in DNA

Angewandte Chemie, Volume 138, Issue 23, 1 June 2026.
Two BN‐chromophore‐extended nucleosides containing electronically complementary BNB‐ and NBN‐doped phenalenyls were synthesised and incorporated into deoxyribonucleic acid (DNA) oligonucleotides. These chromophores act as an efficient fluorophore–quencher pair under aqueous conditions.
Sarah Lutz, Hermann Neitz, Michael Müller, Johannes Chorbacher, Konstantin A. Isenberg, Claudia Höbartner, Holger Helten   +6 more
wiley   +2 more sources