Results 271 to 280 of about 323,426 (336)

Denaturation of Nucleic Acids Induced by Intercalating Agents. Biochemical and Biophysical Properties of Acridine Orange-DNA Complexes

Journal of Biomolecular Structure and Dynamics, 1984
At high binding densities acridine orange (AO) forms complexes with ds DNA which are insoluble in aqueous media. These complexes are characterized by high red- and minimal green-luminescence, 1:1 (dye/P) stoichiometry and resemble complexes of AO with ss nucleic acids.
Jan Kapuściński, Zbigniew Darżynkiewicz   +1 more
openalex   +4 more sources

Features of Determining Thermodynamic Parameters of Formation of Nucleic Acid Complexes Using Thermal Denaturation with Fluorimetric Signal Detection

Russian journal of bioorganic chemistry, 2019
G. Shevelev, Marsel R Kabilov, A. Lomzov, I. Dovydenko, D. Pyshnyi   +4 more
semanticscholar   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Isothermal Detection of Canine Blood Parasite (Ehrlichia canis) Utilizing Recombinase Polymerase Amplification Coupled with Graphene Oxide Quenching-Based Pyrrolidinyl Peptide Nucleic Acid.

Bioconjugate chemistry, 2021
Canine monocytic ehrlichiosis (CME), caused by transmitted Ehrlichia canis infection, is a major disease in dogs with worldwide distribution. Herein, a nucleic acid assay was established for the identification of E.
Phanomsak Yukhet, K. Buddhachat, T. Vilaivan, C. Suparpprom   +3 more
semanticscholar   +1 more source

Studies on the Structure of Nucleic Acids. X. On the Mechanism of Denaturation¹

Journal of the American Chemical Society, 1956
Liebe F. Cavalieri, Morton Rosoff, Barbara Hatch Rosenberg   +2 more
openalex   +3 more sources

Direct, sequence-specific detection of dsDNA based on peptide nucleic acid and graphene oxide without requiring denaturation.

Biosensors & bioelectronics, 2014
Jieon Lee, I. Park, Euihan Jung, Younghoon Lee, Dal‐Hee Min   +4 more
semanticscholar   +2 more sources

Synthesis and thermal denaturation studies of novel 2'-O,3'-C-linked bicyclic oligonucleotides with a methoxy or a piperazino group facing the major groove of nucleic acid duplexes.

Organic and biomolecular chemistry, 2005
M. Raunkjaer, M. Sorensen, J. Wengel
semanticscholar   +2 more sources

Pyridine: a Denaturant or Stabilizer of Spherical Nucleic Acids?

Analytical Chemistry, 2017
The spotlighted dual functions of pyridine as a denaturant and as a stabilizer for duplex DNA are thoroughly investigated using spherical nucleic acids (SNAs). At neutral pH, pyridine destabilizes the duplex interconnects of assembled SNAs, resulting in a gradual decrease in their melting temperature (Tm) as a function of the pyridine concentration ...
Yoon Hyuck Kim, Ju-Hwan Oh, Abigail K. R. Lytton-Jean, Jae-Seung Lee   +3 more
openaire   +2 more sources

Microfluidic chip of fast DNA hybridization using denaturing and motion of nucleic acids [PDF]

ELECTROPHORESIS, 2008
AbstractThis study presents the effect of fluidic temperatures and velocities on improving DNA hybridization. The efficiency of hybridization could be improved by introducing elevated temperature in the hot region and velocity in the cold region. Compared with the conventional methods, this hybridization microchip was able to increase the hybridization
Li-Wei Lai, Qiaole Zhao, Yu-Cheng Lin, Chuan-You Ye, Chuang-Di Chueh, Yung-Chiang Chung   +5 more
openaire   +3 more sources

Analysis and purification of peptide nucleic acids by denaturing PAGE

ELECTROPHORESIS, 2007
AbstractA flexible and convenient protocol for the analysis and purification of peptide nucleic acid (PNA) oligomers and PNA‐peptide chimeras by denaturing PAGE is described. Vertical slab gel electrophoresis, 26% in polyacrylamide and 8 M urea at pH 3, was suitable for analysis of oligomers ranging in size from tetramers (4‐mers) to tetradodecamers ...
Robert H. E. Hudson, David W. Dodd
openaire   +2 more sources

Locked Nucleic Acids and Intercalating Nucleic Acids in the Design of Easily Denaturing Nucleic Acids: Thermal Stability Studies

ChemBioChem, 2004
AbstractIntercalating nucleic acids (INA®s) with insertions of (R)‐1‐O‐(1‐pyrenylmethyl)glycerol were hybridized with locked nucleic acids (LNAs). INA/LNA duplexes were found to be less stable than the corresponding DNA/LNA duplexes when the INA monomer was inserted as a bulge close to the LNA monomers in the opposite strand.
Filichev, V.V., Hilmy, K.M.H., Christensen, Ulf B., Pedersen, Erik Bjerreg., Babu, Bolle Ravindra, Wengel, Jesper   +5 more
openaire   +4 more sources