Microfluidic-Based Nucleic Acid Amplification Systems in Microbiology
Micromachines, 2019 Rapid, sensitive, and selective bacterial detection is a hot topic, because the progress in this research area has had a broad range of applications.
Lena Gorgannezhad +2 more
doaj +2 more sources
CRISPR/Cas-based nucleic acid detection strategies: Trends and challenges
HeliyonCRISPR/Cas systems have become integral parts of nucleic acid detection apparatus and biosensors. Various CRISPR/Cas systems such as CRISPR/Cas9, CRISPR/Cas12, CRISPR/Cas13, CRISPR/Cas14 and CRISPR/Cas3 utilize different mechanisms to detect or ...
Jian Zhou +3 more
doaj +2 more sources
Towards a lab-on-chip sensor: chemiluminescence-based DNA-nanomachine for nucleic acid detection at zeptomolar concentrations [PDF]
, 2023 This study presents a unique peroxidase-like DNA-nanomachine (PxDm)-based nucleic acid detection technique that could transform healthcare through providing rapid and accurate identification of infectious diseases at the point-of-care (POC) format.
Pavel, Filatov +4 more
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Electrochemical nucleic acid-based sensors for detection of E. coli and Shiga toxin-producing E. coli (STEC) – Review of the recent developments [PDF]
, 2022 Escherichia coli (E. coli) are a group of bacteria, which are a natural part of the intestinal flora of warm-blooded animals, including humans. Most E.
Kaye, Burgess +5 more
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PNA Microprobe for Label-Free Detection of Nucleic Acid Repeat Mutations [PDF]
, 2021 We present a PNA-based microprobe sensing platform to detect nucleic acid repeat mutations by electrochemical impedance spectroscopy. The microprobe platform discriminated Huntington’s disease-associated CAG repeats in cell-derived total RNA.
Grace, Durocher +4 more
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Building a nucleic acid nanostructure with DNA-epitope conjugates for a versatile electrochemical protein detection platform [PDF]
, 2023 The recent surge of effort in nucleic acid-based electrochemical (EC) sensors has been fruitful, and some have even shown real-time quantification of drugs in the blood of living animals.
Niamat , Khuda +4 more
core +1 more source
CRISPR-cas technology: A key approach for SARS-CoV-2 detection
Frontiers in Bioengineering and Biotechnology, 2023 The CRISPR (Clustered Regularly Spaced Short Palindromic Repeats) system was first discovered in prokaryotes as a unique immune mechanism to clear foreign nucleic acids.
Lijuan Fang +5 more
doaj +1 more source
A CRISPR-based nucleic acid detection method for severe fever with thrombocytopenia syndrome virus
Virus Research, 2022 Objective: Fever with thrombocytopenia syndrome virus (SFTS) is a tick-borne infection now known to spread among humans as an aerosol, which has resulted in several outbreaks across Asia over the past decade.
Yansong Zhang +15 more
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Advances in Nucleic Acid Amplification-Based Microfluidic Devices for Clinical Microbial Detection
Chemosensors, 2022 Accurate and timely detection of infectious pathogens is urgently needed for disease treatment and control of possible outbreaks worldwide. Conventional methods for pathogen detection are usually time-consuming and labor-intensive.
Thi Ngoc Diep Trinh, Nae Yoon Lee
doaj +1 more source
Algorithms for Nucleic Acid Sequence Design [PDF]
, 2010 Motivated by a growing field of research focused on programming function into biomolecules, we seek to decrease the cost of high-quality rational nucleic acid sequence design while increasing its versatility and availability.
Zadeh, Joseph N.
core +1 more source