Results 1 to 10 of about 48,779 (251)
Nitrogen heterocycles form peptide nucleic acid precursors in complex prebiotic mixtures [PDF]
Scientific Reports, 2019 The ability to store information is believed to have been crucial for the origin and evolution of life; however, little is known about the genetic polymers relevant to abiogenesis.
Laura E. Rodriguez +4 more
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EFFECTS OF NUCLEIC ACID PRECURSORS ON LIVER INJURIES
THE JOURNAL OF VITAMINOLOGY, 1967 AICA and AICA orotate were given in massive doses together with 20% casein diet to rats with liver injuries induced by a low protein, amino acid imbalanced diet, and the effects of both agents appraised.AICA orotate was apparently of value in recovering iodine numbers of fatty acids in liver lipids, increasing Palade granules and inhibiting fibrosis ...
Shuji Hashimoto
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Decoding Mycoplasma Nucleases: Biological Functions and Pathogenesis [PDF]
ToxinsNucleases are critical metabolic enzymes expressed by mycoplasmas to acquire nucleic acid precursors from the host for their parasitic existence. Certain nucleases, either membrane-bound or secreted, not only contribute to the growth of mycoplasmas but ...
Xinchao Yi +10 more
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An all-purine precursor of nucleic acids. [PDF]
Proceedings of the National Academy of Sciences, 1988 The theory is proposed that the pyrimidines in extant nucleic acids are postenzymatic substitutes for their isoelectronic and isogeometric position 3-bonded purine analogs xanthine and isoguanine, which were sibling products in a preenzymatic de novo purine pathway.
Günter Wächtershäuser
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Nucleic Acid Precursor Requirements of Mycoplasma laidlawii
Journal of General Microbiology, 1962 SUMMARY: The nucleic acid precursor requirements of Mycoplasma laidlawii strain A were determined by using a partially defined medium. Adenine, guanosine and cytidine were found to be the minimal growth requirements. However, best growth was obtained with undegraded RNA or oligoribo-nucleotides.
B. S. RAZIN
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Stimulation of incorporation of nucleic acid precursors into HeLa cells caused by provaline [PDF]
Biochemical Journal, 1969 1. The effect of proflavine and other acridines on the incorporation of precursors into the nucleic acids of HeLa cells was examined. 2. Relatively low concentrations (50μm) of proflavine completely inhibited incorporation of precursors into DNA, but allowed a small extent of incorporation into RNA. 3.
J. W. Watts
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Polyamines and nucleic acid metabolism in chick embryo. Incorporation of labelled precursors into nucleic acids of subcellular fractions and polyribosomal patterns [PDF]
Biochemical Journal, 1968 1. An increase in polyamine concentration, caused by inhibiting the amine oxidase activities with iproniazid, increased the incorporation of [3H]orotic acid into chick-embryo RNA and DNA. On the other hand, a decrease in polyamine concentration, obtained by causing an increase in amine oxidase activities, decreased [3H]orotic acid incorporation into ...
G. Moruzzi +2 more
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Incorporation of Protein and Nucleic Acid Precursors into Frog Nervous Tissue in vitro, [PDF]
Experimental Biology and Medicine, 1966 Effects of 1, 1, 3-tricyano-2-aminopropene /TCAP/ on incorporation of protein and nucleic acid precursors into frog nervous system in ...
Jacob Shapira +2 more
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Photochemical synthesis of natural lipids in artificial and living cells [PDF]
Nature CommunicationsLipid synthesis plays a central role in cell structure, signaling, and metabolism. A general method for the abiogenesis of natural lipids could transform the development of lifelike artificial cells and unlock new ways to explore lipid functions in ...
Peng Ji +6 more
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Uptake of amino acids and nucleic acid precursors by regenerating rat liver [PDF]
Biochemical Journal, 1972 1. At 0.5–1.0h after partial hepatectomy the intracellular acid-soluble fraction of rat liver took up twice as much radioactivity from [3H]orotic acid, [3H]uridine and [3H]thymidine as did similar fractions from sham-operated animals. This increase in penetration was not prevented by adrenalectomy or actinomycin, both of which decreased precursor ...
Margery G. Ord, L. A. Stocken
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