Nitrogen heterocycles form peptide nucleic acid precursors in complex prebiotic mixtures [PDF]
The ability to store information is believed to have been crucial for the origin and evolution of life; however, little is known about the genetic polymers relevant to abiogenesis.
Laura E. Rodriguez +4 more
doaj +2 more sources
Characterization of Gastrointestinal Absorption of Salmon Milt-Derived Oligodeoxyribonucleic Acids in Mice [PDF]
Dietary nucleic acids exert physiological effects beyond serving as substrates for nucleic acid synthesis; however, their exact molecular forms that are absorbed in the small intestine remain unclear.
Fuyu Hayashi +8 more
doaj +2 more sources
NUCLEIC ACID PRECURSORS AND PROTEIN SYNTHESIS [PDF]
Arthur B Pardee, Pardee Arthur B
exaly +3 more sources
Fluorescent Nanoparticles Synthesized from DNA, RNA, and Nucleotides
Ubiquitous on Earth, DNA and other nucleic acids are being increasingly considered as promising biomass resources. Due to their unique chemical structure, which is different from that of more common carbohydrate biomass polymers, materials based on ...
Maofei Wang +3 more
doaj +1 more source
Highly nonlinear optic nucleic acid thin-solid film to generate short pulse laser
Using aqueous precursors, we report successfully fabricating thin-solid films of two nucleic acids, ribonucleic acid (RNA) and deoxyribonucleic acid (DNA).
Marjan Ghasemi +7 more
doaj +1 more source
Chronic low-grade inflammation underlies the pathogenesis of non-communicable diseases, including chronic kidney diseases (CKD). Inflammation is a biologically active process accompanied with biochemical changes involving energy, amino acid, lipid and ...
Takahiko Nakagawa +10 more
doaj +1 more source
Recent Advances in Chemical Biology Using Benzophenones and Diazirines as Radical Precursors
The use of light-activated chemical probes to study biological interactions was first discovered in the 1960s, and has since found many applications in studying diseases and gaining deeper insight into various cellular mechanisms involving protein ...
Muhammad Murtaza Hassan +1 more
doaj +1 more source
Deep Eutectic Solvents as Media for the Prebiotic DNA-Templated Synthesis of Peptides
Translation of genetic information into peptide products is one of the fundamental processes of biology. How this occurred prebiotically, in the absence of enzyme catalysts, is an intriguing question.
Samuel Núñez-Pertíñez +1 more
doaj +1 more source
Nicotinamide adenine dinucleotide and the sirtuins caution: Pro‐cancer functions
This scoping review aims to perform a brief but comprehensive assessment of existing peer‐reviewed literature and determine whether raising nicotinamide adenine dinucleotide can prevent or promote tumorigenesis. The examination of extensive peer‐reviewed
Raymond D. Palmer, Mauro Vaccarezza
doaj +1 more source
A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration.
Several human neurodegenerative disorders are characterized by the accumulation of 8-oxo-7,8-dihydroguanine (8-oxodG) in the DNA of affected neurons.
Gabriele De Luca +13 more
doaj +1 more source

