Results 141 to 150 of about 191,094 (249)

Beyond Misfolding: A New Paradigm for the Relationship Between Protein Folding and Aggregation. [PDF]

Int J Mol Sci
Choi SI, Jin Y, Choi Y, Seong BL.
europepmc   +1 more source

Microscopic Origins of Flow Activation Energy in Biomolecular Condensates. [PDF]

J Phys Chem B
Yang S, Banerjee PR, Potoyan DA.
europepmc   +1 more source

3P104Update of ProNIT : Thermodynamic Database for Protein-Nucleic Acid Interactions

Seibutsu Butsuri, 2001
Akinori Sarai, Hirohiko Kono, Jianghong An, M. Michael Gromiha, Ponraj Prabakaran, H. Uedaira, Samuel Selvaraj   +6 more
openaire   +3 more sources

DNA‐Binding Properties of Non‐Intercalating Water‐Soluble Organometallic Ir(III) Luminophores

Chemistry – A European Journal, Volume 31, Issue 30, May 27, 2025.
A series of water‐soluble, organometallic iridium(III) complexes has been studied with respect to their DNA binding behavior. A combined biophysical and computational study reveals the subtle interplay of non‐intercalative DNA binding events that are modulated by small changes in ligand structure. Abstract A series of Ir(III) complexes, [Ir(C^N)2(en)]+
Ibrahim S. Alkhaibari, Peter N. Horton, Simon J. Coles, Niklaas J. Buurma, Simon J. A. Pope   +4 more
wiley   +1 more source

Electrostatic Anchoring in RNA-Ligand Design─Dissecting the Effects of Positive Charges on Affinity, Selectivity, Binding Kinetics, and Thermodynamics. [PDF]

J Med Chem
Almena Rodriguez L, Kallert E, Husmann JÅ, Schaubruch K, Meisel KIS, Schwickert M, Hoba SN, Heermann R, Kersten C.   +8 more
europepmc   +1 more source

Click Conjugates of Artificial Ribonucleases: Sequence Specific Cleavage with Multiple Turnover

Chemistry – A European Journal, Volume 31, Issue 30, May 27, 2025.
A trisbenzimidazole catalyst was attached to central positions of DNA and DNA‐LNA oligonucleotides. The resulting conjugates bind complementary RNA strands and cleave them with multiple turnover and substrate half‐lives down to 3.5 hours. Up to 98.8% of cleavage occurs in a single site.
Sandra Weber, Timo Weinrich, Ute Scheffer, Elisabeth Kalden, Michael W. Göbel   +4 more
wiley   +1 more source

Controlling DNA-RNA strand displacement kinetics with base distribution. [PDF]

Proc Natl Acad Sci U S A
Ratajczyk EJ, Bath J, Šulc P, Doye JPK, Louis AA, Turberfield AJ.   +5 more
europepmc   +1 more source

Three- and four-stranded nucleic acid structures and their ligands. [PDF]

RSC Chem Biol
Hashimoto Y, Shil S, Tsuruta M, Kawauchi K, Miyoshi D.   +4 more
europepmc   +1 more source

Impact of a single 8-oxoguanine lesion on Watson-Crick and Hoogsteen base pair hybridization in telomeric DNA quantified using single-molecule force spectroscopy. [PDF]

Nucleic Acids Res
Cheng Y, Wang X, Yang X, Zhang Y, You H.
europepmc   +1 more source

Harnessing Information Thermodynamics: Conversion of DNA Information into Mechanical Work in RNA Transcription and Nanopore Sequencing. [PDF]

Entropy (Basel)
Tsuruyama T.
europepmc   +1 more source