Results 141 to 150 of about 221,973 (265)

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

Cell Proliferation, Volume 59, Issue 2, February 2026.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie, Ting Wang, Xin‐ran Liu, Yan Wang, Qin Dang, Tian Ding, Jia‐qi Xu, Xian‐jun Yu, Hai Lin, Xiao‐wu Xu, Yi Qin   +10 more
wiley   +1 more source

Transcriptional outputs and condensates – formation and function

New Phytologist, Volume 249, Issue 3, Page 1145-1154, February 2026.
Summary The dynamic spatiotemporal organization of macromolecules is key to the proper function of the cell, allowing the exquisite regulation of diverse processes from gene expression to enzymatic function. The formation of biomolecular condensates via phase separation (PS) acts as a general mechanism for selectively concentrating proteins, nucleic ...
Stephanie Hutin, Jiawei Li, Mark D. Tully, Xuelei Lai, Chloe Zubieta   +4 more
wiley   +1 more source

ASOG: AntiSense Oligonucleotide Generator. [PDF]

Comput Struct Biotechnol J
Kimi J, Korczak P, Vialet B, Roubin E, Barthélémy P, Campagne S, Malard F.   +6 more
europepmc   +1 more source

Complex Thermodynamic Behavior of Single-Stranded Nucleic Acid Adsorption to Graphene Surfaces.

Langmuir, 2016
Srivathsan V Ranganathan, Ken Halvorsen, Christopher A. Myers, Neil M. Robertson, M. Yigit, Alan A. Chen   +5 more
semanticscholar   +1 more source

3PA120 Thermodynamic Database for Protein-Nucleic Acid Interactions

Seibutsu Butsuri, 1999
P. Prabakaran, J. An, M. M. Gomiha, H. Uedaira, H. Kono, A. Sarai   +5 more
openaire   +1 more source

Crucial Role of Oxidation for the Prebiotic Peptide Elongation Promoted by Carbonyl Sulfide

European Journal of Organic Chemistry, Volume 29, Issue 1, January 12, 2026.
The prebiotic activation of amino acid (AA) into peptides via N‐carboxyanhydride (NCA), promoted by carbonyl sulfide (COS), cannot proceed without an oxidizing step (enabling better leaving groups than sulfur dianion). While being efficient even at mild pH the prebiotic scope of COS promoted activation of AA, it is however limited because side ...
Alexandre Desfoux, Jean‐Christophe Rossi, Laurent Boiteau, Gaulthier Rydzek, Robert Pascal   +4 more
wiley   +1 more source

Contributions of the Histidine Side Chain and the N-Terminal α-Amino Group to the Binding Thermodynamics of Oligopeptides to Nucleic Acids as a Function of pH

, 2010
Jeff D. Ballin, James P. Prevas, Christina R. Ross, Eric A. Toth, Gerald M. Wilson, M. Thomas Record   +5 more
openalex   +2 more sources

Nucleic acid base pair open states by hydrogen exchange. [PDF]

Proc Natl Acad Sci U S A
Englander SW.
europepmc   +1 more source

Kinetic and thermodynamic analysis of triplex formation between peptide nucleic acid and double-stranded RNA.

Organic and biomolecular chemistry, 2018
Takaya Sato, N. Sakamoto, S. Nishizawa
semanticscholar   +1 more source

Multimodal investigation of dacomitinib-calf thymus DNA binding interaction: insights from spectroscopy, thermodynamics, and in-silico studies. [PDF]

RSC Adv
Alossaimi MA, Aldakhil T, Elmansi H, Belal F, Magdy G.   +4 more
europepmc   +1 more source