Results 161 to 170 of about 34,544 (276)

High-throughput DNA melt measurements enable improved models of DNA folding thermodynamics. [PDF]

Nat Commun
Ke Y, Sharma E, Wayment-Steele HK, Becker WR, Ho A, Marklund E, Greenleaf WJ.   +6 more
europepmc   +1 more source

Origin of life: β‐sheet amyloid conformers as the primordial functional polymers on the early Earth and their role in the emergence of complex dynamic networks

FEBS Letters, Volume 599, Issue 19, Page 2693-2705, October 2025.
The amyloid world hypothesis of the origin‐of‐life posits that the first functional polymers on the early Earth were structurally stable cross‐β‐sheet‐based peptide amyloids capable of Darwinian‐like evolution. Peptide amyloids display self‐replication and information transfer, as well as catalytic, adaptive, and evolutive properties.
Carl Peter J. Maury
wiley   +1 more source

Advances in nucleic acid probe-based detection of gene point mutations: a review. [PDF]

Front Chem
Pu X, Wu X.
europepmc   +1 more source

Designing the Next Generation of Biomaterials through Nanoengineering

Advanced Materials, Volume 37, Issue 39, October 2, 2025.
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr., Ishaan Duggal, Nicholas A. Peppas, Akhilesh K. Gaharwar   +3 more
wiley   +1 more source

Twisting tetraplex DNA: A strand dynamics regulating i-motif function in diverse molecular crowding environments. [PDF]

Nucleic Acids Res
Takahashi S, Ghosh S, Trajkovski M, Ohyama T, Plavec J, Sugimoto N.   +5 more
europepmc   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, Volume 37, Issue 42, October 23, 2025.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

FitFoldData: A Web-Based Toolkit for Circular Dichroism and Differential Scanning Calorimetry Data Analysis of Protein Thermal Denaturation. [PDF]

ACS Omega
Yeritsyan KV, Badasyan AV.
europepmc   +1 more source

Artificial Intelligence‐Driven Nanoarchitectonics for Smart Targeted Drug Delivery

Advanced Materials, Volume 37, Issue 42, October 23, 2025.
This perspective introduces an artificial intelligence (AI)‐driven nanoarchitectonics framework for targeted drug delivery, combining database‐guided nanocarrier design, machine learning (ML)‐assisted surface engineering with a designed targeting system, and in silico modeling for dynamic optimization.
Hayeon Bae, Hyunsub Ji, Konstantin Konstantinov, Ronald Sluyter, Katsuhiko Ariga, Yong Ho Kim, Jung Ho Kim   +6 more
wiley   +1 more source

DNA calorimetric force spectroscopy at single base pair resolution. [PDF]

Nat Commun
Rissone P, Rico-Pasto M, Smith SB, Ritort F.   +3 more
europepmc   +1 more source

Synthesis, Properties, and Typical Applications of MXene‐Based Heterostructure Materials

Advanced Materials Interfaces, Volume 12, Issue 19, October 6, 2025.
In recent years, MXene‐based heterostructure materials have achieved fruitful outcomes in multiple aspects. However, a comprehensive and systematic summary of MXene‐based heterostructures is still absent. This review summarizes the performance characteristics, synthesis methods, and the latest research progress of MXene heterostructures in several ...
Baoquan Xiao, Zelin Gao, Hengbiao Zhang, Jiantao Zhang, Shiyuan Wang, Gang Long, Shenghu Wei, Jixing Huang, Runqi Yao, Xingdong Jiang, Fei Ma, Xusheng Xia, Liyun Ding   +12 more
wiley   +1 more source