Results 171 to 180 of about 34,544 (276)

The Effect of 2'F-RNA on I-Motif Structure and Stability. [PDF]

Molecules
Ugedo C, Domínguez A, Gómez-Pinto I, Eritja R, González C, Aviñó A.   +5 more
europepmc   +1 more source

3P104Update of ProNIT : Thermodynamic Database for Protein-Nucleic Acid Interactions

Seibutsu Butsuri, 2001
Akinori Sarai, Hirohiko Kono, Jianghong An, M. Michael Gromiha, Ponraj Prabakaran, H. Uedaira, Samuel Selvaraj   +6 more
openaire   +3 more sources

Cascade‐Targeted Nanoparticles for Enhanced Gemcitabine Delivery and Adenosine Metabolism Modulation to Overcome Treatment Resistance in Pancreatic Cancer

Advanced Science, Volume 12, Issue 38, October 13, 2025.
The aberrant adenosine metabolism leads to chemoresistance and immunosuppressive microenvironment. A versatile albumin‐polyplexes conjugated nanoparticle B‐PDEA@CPA is prepare for the codelivery of gemcitabine and siCD39. The nanoparticle releases gemcitabine‐loaded albumin upon microenvironment to achieve promoted penetration and cellular uptake ...
Hongrui Fan, Hongyi Chen, Haolin Song, Chufeng Li, Yu Wang, Zhenhao Zhao, Qin Guo, Xuwen Li, Mingxuan Liu, Tao Sun, Chen Jiang   +10 more
wiley   +1 more source

Precision‐Arranged DNA Origami Plasmonic Nanoantennas for Multidimensional Smart‐Warning of Weightlessness Induced Bone Loss

Advanced Science, Volume 12, Issue 40, October 27, 2025.
It is synthesized precision‐arranged DNA origami plasmonic nanoantennas for multiplexed and intelligent warning of bone loss induced by microgravity and radiation. The ordered nanoantennas simultaneously and accurately detected calcium ions, interleukin‐6, and microRNA‐214 in serum from mice exposed to microgravity and radiation, with performance ...
Yufan Ling, Xuan Qin, Weijia Sun, Fan Yue, Yiwei Wang, Di Fan, Haoyuan Xu, Ruao Xie, Jiawei Zhang, Jianwei Li, Bingyan Li, Yang Yang, Yingxian Li, Houyu Wang, Guangming Zhou   +14 more
wiley   +1 more source

RNA Binding Mechanism of the FUS Zinc Finger in Concert with Its Flanking Intrinsically Disordered Region. [PDF]

J Chem Inf Model
Kijima S, Kitao A.
europepmc   +1 more source

Polyphenol‐Based Functional Materials: Structural Insights, Composite Strategies, and Biomedical Applications

Advanced Science, Volume 12, Issue 39, October 20, 2025.
This schematic representation illustrates the interaction mechanisms between polyphenolic compounds and various materials (metals, proteins, polysaccharides, alkaloids, etc.). And explains the potential clinical application value of these materials (nanoparticles, coatings, films, capsules, and hydrogels constructed using polyphenols) in the fields of ...
Songwen Xue, Wen Tan, Shuifang Mao, Haibo Pan, Xingqian Ye, Natthawuddhi Donlao, Jinhu Tian   +6 more
wiley   +1 more source

Recent advances in CRISPR-based single-nucleotide fidelity diagnostics. [PDF]

Commun Med (Lond)
Kohabir KAV, Sistermans EA, Wolthuis RMF.   +2 more
europepmc   +1 more source

The Evolution of Functional Amyloids and Their Impact on Host–Microbe Interactions

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This review describes functional amyloids and highlights the importance of structural repetition and molecular mimicry that distinguish the amyloid fold. The authors describe how amyloid can be the last universal common ancestor of protein folds. The authors also discuss how microbes utilize functional amyloids and how the structural characteristics of
Divya Kolli, Saroj K. Rout, Roland Riek, Matthew R. Chapman   +3 more
wiley   +1 more source

Revolutionizing tumor diagnosis and treatment: the promise of DNA nanotechnology. [PDF]

Front Immunol
Zhou Y, Wang N.
europepmc   +1 more source

Lactate Dehydrogenase C4 Accelerates Triple‐Negative Breast Cancer Progression by Promoting Acetyl‐CoA Acyltransferase 2 Lactylation to Increase Free Fatty Acid Accumulation

Advanced Science, Volume 12, Issue 40, October 27, 2025.
Diagram of the reprogramming of FA metabolism mediated by LDHC4‐induced ACAA2 activity to promote TNBC progression. LDHC4 drives TNBC progression by enhancing ACAA2‐mediated fatty acid production. The resulting accumulation of FFAs stimulates autophagy and accelerates cell cycle progression, thereby promoting tumor growth.
Zhaolei Cui, Chaoqiang Zheng, Yingying Lin, Zhenzhou Xiao, Yanhong Li, Wei Peng, Shijie He, Anyang Li, Xiufeng Wu, Yan Chen, Yang Sun   +10 more
wiley   +1 more source