Results 181 to 190 of about 34,544 (276)

Benchmarking the Base Randomization Algorithm as a Possible Tool for the Initial Step of Generating a Virtual RNA Aptamers Library. [PDF]

BioTech (Basel)
Mokgopa KP, Oloniiju SD, Lobb KA, Tshiwawa T.   +3 more
europepmc   +1 more source

Rapid and Ultra‐Sensitive SARS‐CoV‐2 Subgenomic RNA Detection Using Single‐Molecule With a Large Transistor‐SiMoT Bioelectronic Platform

Advanced Electronic Materials, Volume 11, Issue 17, October 20, 2025.
The single‐molecule with a large transistor‐SiMoT is proposed for the detection of the subgenomic RNA of SARS‐CoV‐2, achieving a diagnostic sensitivity of 98.0% and a specificity of 87.8%. The SiMoT technology, currently at TRL‐5, is suitable for point‐of‐care settings and delivers the result to the end user in 30 min.
Eleonora Macchia, Anna Maria D'Erchia, Mariapia Caputo, Angelica Bianco, Claudia Leoni, Francesca Intranuovo, Cecilia Scandurra, Lucia Sarcina, Cinzia Di Franco, Paolo Bollella, Gaetano Scamarcio, Luisa Torsi, Graziano Pesole   +12 more
wiley   +1 more source

Inverted Molecular Beacons as Reaction-Based Hybridization Probes for Small-Molecule Activation by Nucleic Acid Inputs. [PDF]

ACS Chem Biol
Emanuelson C, Bardhan A, Ankenbruck N, Boette J, Deiters A.   +4 more
europepmc   +1 more source

Nanoparticles Functionalized with Polymer Brushes for Gene Delivery

Advanced NanoBiomed Research, Volume 5, Issue 10, October 2025.
The engineering of the next generation gene delivery vectors requires the precise control of the architecture and physicochemical interactions controlling the transport, targeting, uptake, and release of nucleic acid materials to targeted cells. Polymer brush‐functionalized nanomaterials offer unprecedented control over such design and properties, and ...
Carlos E. Neri‐Cruz, Julien E. Gautrot
wiley   +1 more source

pHEAA/pMA-DNA Hydrogel Sensing Platform for Detecting Drug-Resistant Gene Variants in <i>Mycobacterium tuberculosis</i>. [PDF]

ACS Meas Sci Au
Sun T, Li S, Mohan B, Yu Y, Sun W.
europepmc   +1 more source

Predicting rare DNA conformations via dynamical graphical models: a case study of the B→A transition. [PDF]

Nucleic Acids Res
De Silva N, Perez A.
europepmc   +1 more source

Deciphering the Toxicity of Metal Tungstates and Molybdates: Effects on L929 Cell Metabolic Activity, Oxidative Stress, and Genotoxicity

Journal of Applied Toxicology, Volume 45, Issue 10, Page 2197-2216, October 2025.
ABSTRACT The increasing development and application of metal‐based materials in biomedical and environmental fields raise important concerns regarding their potential cytotoxic and genotoxic effects. Metal tungstates (MxWO4) and molybdates (MxMoO4) offer promising functional properties in health and environmental solutions but require safety validation
Marcelo Assis, Amanda de Souza, Karolyne dos Santos Jorge Sousa, Diana Gabriela Nina Nina, Mirian Bonfacio, Renata Neves Granito, Ana Claudia Muniz Rennó   +6 more
wiley   +1 more source

Enhancing aptamer selection in alzheimer's disease: integrating structure prediction and molecular dynamics simulations. [PDF]

Sci Rep
Lohnes BJ, Goff AJ, Hartwig UF, Poddar NK.   +3 more
europepmc   +1 more source

Solvation, geometry, and assembly of the tobacco mosaic virus. [PDF]

PNAS Nexus
Spirandelli I, Evans ME.
europepmc   +1 more source

Recent Advancements in Graphene Quantum Dot‐Based Bioimaging and Drug Delivery Systems

MedComm, Volume 6, Issue 10, October 2025.
This article reviews recent advancements and the roles of GQDs in healthcare, with a particular focus on different synthesis methods for GQDs, including top‐down and bottom‐up approaches. It also examines the biological, optical, and toxicological attributes of GQDs, as well as their applications in bioimaging and drug delivery.
Sachin Kadian, Shubhangi Shukla, Amit K. Yadav, Brahamdutt Arya, Sushant Sethi, Vishal Chaudhary, Roger Narayan   +6 more
wiley   +1 more source