Results 211 to 220 of about 34,544 (276)
Can the origin of biosynthetic routes be explained by a Frankenstein's monster-like spontaneous assembly of prebiotic reactants? [PDF]
Philos Trans R Soc Lond B Biol SciNegrón-Mendoza A +2 more
europepmc +1 more source
Ligase-catalyzed transcription and reverse-transcription of XNA-containing nucleic acid polymers using T3 DNA ligase. [PDF]
Chem SciKhamissi N +3 more
europepmc +1 more source
Thermodynamics of nucleic acids and their interactions with ligands
Quarterly Reviews of Biophysics, 2000 1. Introduction 2551.1 General thermodynamics 2562. Nucleic acid thermodynamics 2602.1 DNA duplexes 2612.2 RNA duplexes 2632.3 Hybrid DNA–RNA duplexes 2642.4 Hydration 2672.5 Conformational flexibility 2692.6 Thermodynamics 2723. Nucleic acid–ligand interactions 2773.1 Minor groove binders 2783.2 DNA intercalators 2843.3 Triple-helical systems 2883.3.1
Andrew N. Lane, Terence C. Jenkins
openalex +4 more sources
Statistical thermodynamics of nucleic acid melting transitions with coupled binding equilibria
Biopolymers, 1971 AbstractEquations are developed to describe the shift in the temperature of the helix–coil transition when small molecules bind to nucleic acids. Included are high polymers, oligonucleotides, and oligomer–polymer interactions. The equations prescribe simple ways of plotting experimental data to evaluate transition and binding parameters.
Donald M. Crothers
openalex +4 more sources
ChemInform, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Vladimir A. Basiuk
openalex +3 more sources
Hydrodynamics, Thermodynamics and Scattering Properties: Nucleic Acids, Nucleosomes and Chromatin
, 1985 Though the progress of both experimental and theoretical chemistry has been steady since the eighteenth century, it was only in our lifetime that the nature of the macromolecular state was clearly established. Until about fifty years ago it was generally believed that large, covalently bonded, well defined macromolecules do not exist, and only ill ...
Henryk Eisenberg
openalex +3 more sources
Thermodynamics and Kinetics‐Directed Regulation of Nucleic Acid‐Based Molecular Recognition
Small MethodsAbstractNucleic acid‐based molecular recognition plays crucial roles in various fields like biosensing and disease diagnostics. To achieve optimal detection and analysis, it is essential to regulate the response performance of nucleic acid probes or switches to match specific application requirements by regulating thermodynamics and kinetics properties.
Yihao Liu +5 more
openalex +3 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
[24] Thermodynamics of ligand-nucleic acid interactions
1992Ligand-and protein-DNA equilibria are extremely sensitive to solution conditions (e.g., salt, temperature, and pH), and, in general, the effects of different solution variables are interdependent (i.e., linked). As a result, an assessment of the basis for the stability and specificity of ligand-or protein-DNA interactions requires quantitative studies ...
David P. Mascotti, Timothy M. Lohman
openaire +3 more sources
A Spectroscopic and Thermodynamic Study of Taxol Nucleic Acid Complexes
Nucleosides and Nucleotides, 1999The interactions of natural and synthetic polynucleotide double strands with the antitumor agent paclitaxel and the oncological product "Taxol for Injection Concentrate" (abbreviated as taxol) were examined in diluted aqueous solutions by thermal denaturation profiles (Tm), CD spectra and UV-absorption measurements.
Ulrich Gromann +4 more
openaire +3 more sources