Results 211 to 220 of about 215,794 (272)
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Thermodynamic database supports deciphering protein–nucleic acid interactions
Trends in Biotechnology, 2023The thermodynamics of protein-nucleic acid interactions (PNIs) is crucial for elucidating the mechanisms of molecular recognition and pathological consequences. The Protein-Nucleic Acid Thermodynamics Database (PNATDB) is a database containing experimentally determined thermodynamic parameters along with sequence, structural, and function data, which ...
Long-Can Mei, Ge-Fei Hao, Guang-Fu Yang
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Thermodynamic databases for proteins and protein-nucleic acid interactions
Biopolymers, 2001Thermodynamic data regarding proteins and their interactions are important for understanding the mechanisms of protein folding, protein stability, and molecular recognition. Although there are several structural databases available for proteins and their complexes with other molecules, databases for experimental thermodynamic data on protein stability ...
Ponraj Prabakaran +7 more
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Thermodynamic study of hybridization properties of heterochiral nucleic acids
Biochemical and Biophysical Research Communications, 2003Heterochiral DNA and RNA heptamers, which contained an unnatural L-nucleotide, were synthesized, and thermodynamic analyses of their hybridization properties with complementary DNA and RNA strands were systematically conducted by UV melting experiments.
Hidehito Urata +4 more
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Synthesis and thermodynamics of peptide nucleic acid-conjugates
2023Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the School of Molecular Sciences, Faculty of Science Technology and Engineering, La Trobe University, Bundoora.
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Thermodynamics and kinetics of co-operative protein-nucleic acid binding
Journal of Molecular Biology, 1983 Fumiyuki Watanabe, Gerhard Schwarz
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Selective Enrichment of Low‐Abundance DNA Variants Based on Programmable Peptide Nucleic Acid Probes
Chinese journal of chemistrySingle‐nucleotide variants (SNVs) are crucial in disease development, but their accurate detection is challenging due to their low abundance and interference from wild‐type targets.
Yi Zhang +6 more
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Biochemistry, 2008
A locked nucleic acid (LNA) monomer is a conformationally restricted nucleotide analogue exhibiting enhanced hybridization efficiency toward complementary strand.
Harleen Kaur, J. Wengel, S. Maiti
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A locked nucleic acid (LNA) monomer is a conformationally restricted nucleotide analogue exhibiting enhanced hybridization efficiency toward complementary strand.
Harleen Kaur, J. Wengel, S. Maiti
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Thermodynamic Characterization of Nucleic Acid Nanoparticles Hybridization by UV Melting
2023The advances in nucleic acid nanotechnology have given rise to various elegantly designed structural complexes fabricated from DNA, RNA, chemically modified RNA strands, and their mixtures. The structural properties of NA nanoparticles (NANP) generally dictate and significantly impact biological function; and thus, it is critical to extract information
Megan, Teter +3 more
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THERMODYNAMIC PROFILE OF INTERACTION OF PORPHYRINS WITH NUCLEIC ACIDS
2007The binding of a number of novel water soluble porphyrins to nucleic acids (NA) were studied monitoring the changes in Soret region of absorbance spectra, fluorescence spectra and circular dichroism (CD) spectra of formed complexes. The binding modes for all complexes were dtermined. The binding isotherms were used to calculate the binding constant, Kb,
Tigran V. Chalikian +3 more
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