Results 41 to 50 of about 34,496 (157)
Length and sequence relaxation of copolymers under recombination reactions
, 2017 We describe the kinetics and thermodynamics of copolymers undergoing recombination reactions, which are important for prebiotic chemistry. We use two approaches: the first one, based on chemical rate equations and the mass-action law describes the ...
Blokhuis, Alex, Lacoste, David
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Remnants of an ancient metabolism without phosphate [PDF]
, 2017 Phosphate is essential for all living systems, serving as a building block of genetic and metabolic machinery. However, it is unclear how phosphate could have assumed these central roles on primordial Earth, given its poor geochemical accessibility.
Goldford, Joshua E. +3 more
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Preferential interaction coefficient for nucleic acids and other cylindrical poly-ions
, 2007 The thermodynamics of nucleic acid processes is heavily affected by the electric double-layer of micro-ions around the polyions. We focus here on the Coulombic contribution to the salt-polyelectrolyte preferential interaction (Donnan) coefficient and we ...
Tellez, G., Trizac, E.
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Genome-scale architecture of small molecule regulatory networks and the fundamental trade-off between regulation and enzymatic activity [PDF]
, 2017 Metabolic flux is in part regulated by endogenous small molecules that modulate the catalytic activity of an enzyme, e.g., allosteric inhibition. In contrast to transcriptional regulation of enzymes, technical limitations have hindered the production of ...
Briars, Emma +6 more
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The RNA Newton Polytope and Learnability of Energy Parameters [PDF]
, 2013 Despite nearly two scores of research on RNA secondary structure and RNA-RNA interaction prediction, the accuracy of the state-of-the-art algorithms are still far from satisfactory.
Chitsaz, Hamidreza +1 more
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Coarse-grained simulations of RNA and DNA duplexes
, 2013 Although RNAs play many cellular functions little is known about the dynamics and thermodynamics of these molecules. In principle, all-atom molecular dynamics simulations can investigate these issues, but with current computer facilities, these ...
Cragnolini, Tristan +2 more
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An O(n^5) algorithm for MFE prediction of kissing hairpins and 4-chains in nucleic acids [PDF]
, 2008 Efficient methods for prediction of minimum free energy (MFE) nucleic secondary structures are widely used, both to better understand structure and function of biological RNAs and to design novel nano-structures.
Chen, Ho-Lin +2 more
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, 2014 RNA molecules are essential cellular machines performing a wide variety of functions for which a specific three-dimensional structure is required. Over the last several years, experimental determination of RNA structures through X-ray crystallography and
Cragnolini, Tristan +2 more
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, 2009 Biological macromolecules, proteins and nucleic acids are composed exclusively of chirally pure monomers. The chirality consensus appears vital for life and it has even been considered as a prerequisite of life.
Annila, Arto +2 more
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On the Stabilizing Action of Protein Denaturants: Acetonitrile Effect on Stability of Lysozyme in Aqueous Solutions [PDF]
, 2000 Stability of hen lysozyme in the presence of acetonitrile (MeCN) at different pH values of the medium was studied by scanning microcalorimetry with a special emphasis on determination of reliable values of the denaturational heat capacity change.
Kovriguine, Evgueni, Potekhin, Sergey A.
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