Results 181 to 190 of about 1,078,683 (343)

Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery

Advanced Healthcare Materials, EarlyView.
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang, Yue Hui, Zichao Guo, Dawei Liu, Yun Liu, Huajian Gao, Chun‐Xia Zhao   +6 more
wiley   +1 more source

Design of cationic ionizable lipids for the delivery of therapeutic nucleic acids. [PDF]

Mol Ther Methods Clin Dev
Atmuri NDP, Saadati F, Kulkarni J, Witzigmann D, Cullis PR, Ciufolini MA.   +5 more
europepmc   +1 more source

Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions

Advanced Healthcare Materials, EarlyView.
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang, Bárbara B. Mendes, Dhruv Menon, Jhenifer Oliveira, Xu Chen, Fatma Demir Duman, João Conniot, Sergio Mercado, Xiewen Liu, Shi‐Yuan Zhang, João Conde, Rachel E. Hewitt, David Fairen‐Jimenez   +12 more
wiley   +1 more source

A workflow to define structural classes and classify nucleic acids circular dichroism spectra. [PDF]

QRB Discov
Mosca K, Hoffmann SV, Grangier A, Wien F, Arluison V, Marco S.   +5 more
europepmc   +1 more source

Histochemical Research on Nucleic-Acid, Especially on the Methyl Green-Pyronin Staining of the Pancreatic Cells

, 1954
Tatsuo Suzuki
openalex   +2 more sources

Chromatographic studies on nucleic acids. 3. The nucleic acids of five strains of tobacco mosaic virus [PDF]

, 1950
Roy Markham, Johan Smith
openalex   +1 more source

Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies

Advanced Healthcare Materials, EarlyView.
PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall, Safaa Naiel, Quan Zhou, Pareesa Ali, Tamana Rubina Yousof, Emily Wong, Ricardo Couto, Byron Yépez, Bernhard Seifried, Paul Moquin, Rod Rhem, Myrna Dolovich, Martin Rainer Kolb, Kjetil Ask, Todd Hoare   +14 more
wiley   +1 more source

Light-Activated Molecules Targeting G-Quadruplex Nucleic Acids. [PDF]

Chemistry
Dudek M, Cabanetos C, Deiana M.
europepmc   +1 more source

Recent Work on Nucleic Acids

, 1956
K.V. Shooter
openalex   +1 more source

Formation of Hydroperoxides from Nucleic Acids by Irradiation with X-Rays in Aqueous Systems [PDF]

, 1956
G. Scholes, J. Weiss, Cosette M. Wheeler
openalex   +1 more source