Results 41 to 50 of about 23,431 (250)
Activation pathways of antiviral nucleobases and nucleosides.
, 2018 Activation pathways of antiviral nucleobases and nucleosides.
Robert J. Geraghty (1600762) +3 more
core +1 more source
, 2020 Nucleobases are the main building blocks in DNA and RNA playing very important roles in cell metabolism. Changes of bases in DNA sequence may affect function of products of gene expression - proteins, and this can lead to inherited diseases and most ...
Zemánková, Kristýna +7 more
core +1 more source
Angewandte Chemie, EarlyView.Using NMR and molecular simulations, we map how RNA engages FUS LC‐RGG1 within condensates through electrostatic, π‐stacking, and polar contacts. These multivalent RNA contacts help stabilize RNA within FUS condensates while also reshaping condensate composition and dynamics.
Tongyin Zheng +6 more
wiley +2 more sources
Crystals, 2020 To date, despite the crucial role played by cytosine, uracil, and thymine in the DNA/RNA replication process, no examples showing isomorphic and isostructural behavior among binary co-crystals of natural or modified pyrimidine nucleobases have been so ...
Gustavo Portalone
doaj +1 more source
, 2015 By a combination of ab initio calculations and photoelectron spectroscopy, we demonstrate that the DNA surrounding has only a negligible effect on ionization energies of nucleobases in the native aqueous environment. The aqueous solution thus effectively
Christi Schroeder (1302474) +7 more
core +1 more source
Stabilizing Functional Nucleic Acids for Real‐Sample Diagnostics
Angewandte Chemie, EarlyView.Functional nucleic acids enable programmable real‐sample diagnostics, but often lose function in complex biological matrices. This review highlights four stabilization levers—chemical, topological, architectural, and microenvironment/interface engineering—that preserve aptamer and DNAzyme performance in saliva, serum, urine, and stool, reframing ...
Soyeon Lee +4 more
wiley +2 more sources
Intrinsic fluorescence of nucleobase crystals
Nanoscale Advances, 2023 Nucleobase crystals exhibit intrinsic fluorescence in the visible range and red edge excitation shift.
Ruth Aizen +8 more
openaire +2 more sources
Biomass DNA: An Emerging Building Block for Advanced Materials
Advanced Materials, EarlyView.Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley +1 more source
Rational Molecular Design to Improve Digital Polymer Readout in Aerolysin‐Based Nanopore Sequencing
Angewandte Chemie, EarlyView.Nanopore sensing holds significant yet underexplored potential for decoding synthetic digital polymers. In this study, we synthesized an extensive library of sequence‐defined poly(phosphodiester)s and evaluated their performance in aerolysin‐based sequencing. By systematically optimizing molecular parameters, we identified an ideal combination of coded
Zhaozheng Yang +9 more
wiley +2 more sources
FoodsThe main and most commonly known biological function of nucleobases, nucleosides, and nucleotides is usually associated with the fact that they are the building blocks of nucleic acids. However, these compounds also belong to plant secondary metabolites,
Magdalena Frańska, Rafał Frański
doaj +1 more source