Results 51 to 60 of about 23,431 (250)

The Astrobiology of Nucleobases

The Astrophysical Journal, 2003
Nucleobases are nitrogen heterocycles (N-heterocycles) that are essential components of the genetic material in all living organisms. Extraterrestrial nucleobases have been found in several carbonaceous chondrites, but only in traces. No astronomical data on these complex molecules are currently available. A large fraction of the cosmic carbon is known
Z. Peeters, O. Botta, S. B. Charnley, R. Ruiterkamp, P. Ehrenfreund   +4 more
openaire   +1 more source

Nucleobase modification by an RNA enzyme [PDF]

Nucleic Acids Research, 2016
Ribozymes can catalyze phosphoryl or nucleotidyl transfer onto ribose hydroxyls of RNA chains. We report a single ribozyme that performs both reactions, with a nucleobase serving as initial acceptor moiety. This unprecedented combined reaction was revealed while investigating potential contributions of ribose hydroxyls to catalysis by kinase ribozyme ...
Poudyal, Raghav R., Nguyen, Phuong D. M., Lokugamage, Melissa P., Callaway, Mackenzie K., Gavette, Jesse V., Krishnamurthy, Ramanarayanan, Burke, Donald H.   +6 more
openaire   +2 more sources

Does Stacking Restrain the Photodynamics of Individual Nucleobases?

, 2016
Does Stacking Restrain the Photodynamics of Individual ...
Hans Lischka (1293861), Tomáš Zelený (2051893), Thomas Müller (1276854), Matthias Ruckenbauer (1294329), Pavel Hobza (1279320), Dana Nachtigallová (1429921), Mario Barbatti (1294332)   +6 more
core   +1 more source

TED1 Promotes the Assembly of SCFD3‐D14‐D53 to Reinforce Strigolactone Signaling in Rice

Advanced Science, EarlyView.
This study identifies TED1 as a positive regulator of strigolactones (SL) signaling in rice. The ted1 mutants display dwarfism and increased tillering with significantly reduced SLs sensitivity. Through its longer C‐terminal region, TED1 interacts with D53 and D14 to promote the assembly of SCFD3‐D14‐D53, thereby facilitating the efficient ...
Sheng Luo, Chuanyin Wu, Miao Feng, Wenfan Luo, Rong Miao, Jinsheng Qian, Fan Wang, Chunlei Zhou, Bojuan Liu, Jiale Shao, Ziqi Xun, Yehui Xiong, Zhichao Zhao, Cailin Lei, Shanshan Zhu, Yulong Ren, Xin Wang, Xiuping Guo, Haiyang Wang, Zichao Li, Zhijun Cheng, Qibing Lin, Jianmin Wan   +22 more
wiley   +1 more source

Time‐Resolved Multidimensional NMR Spectroscopy Reveals the Bifurcated Folding Pathway of a Thrombin‐Binding DNA G4–Azobenzene Derivative Complex

Angewandte Chemie, EarlyView.
A photoswitchable ligand was used to trigger conformational changes within the thrombin binding aptamer DNA G‐Quadruplex. These reversible ligand driven rearrangements were examined by time‐resolved NMR experiments to gain insight of the dynamic folding landscape of the G‐quadruplex.
Jason Martins, Julia Wirmer‐Bartoschek, Harald Schwalbe   +2 more
wiley   +2 more sources

A DFTB study on the electronic response of encapsulated DNA nucleobases onto chiral CNTs as a sequencer

Scientific Reports
Sequencing the DNA nucleobases is essential in the diagnosis and treatment of many diseases related to human genes. In this article, the encapsulation of DNA nucleobases with some of the important synthesized chiral (7, 6), (8, 6), and (10, 8) carbon ...
Seyyed Mostafa Monavari, Nafiseh Memarian   +1 more
doaj   +1 more source

Recent Advances in Affinity MOF-Based Sorbents with Sample Preparation Purposes

Molecules, 2020
This review summarizes the recent advances concerning metal–organic frameworks (MOFs) modified with several biomolecules (e.g., amino acids, nucleobases, proteins, antibodies, aptamers, etc.) as ligands to prepare affinity-based sorbents for application ...
Héctor Martínez Pérez-Cejuela, José Manuel Herrero-Martínez, Ernesto F. Simó-Alfonso   +2 more
doaj   +1 more source

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

Advanced Science, EarlyView.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang, Yangfan Huo, Jin Liu, Sida Liu, Minghai Ma, Hao Guo, Yuanquan Zhang, Xing Li, Xiao Liang, Jiawei Xiu, Ying Sun, Lijun Huang, Xiaolong Yan, Weiwei Wu, Lei Wang   +14 more
wiley   +1 more source

RNA Organelles in DNA‐Based Artificial Cells Provide Spatial Aptamer Functions and Enhanced Signal Processing

Angewandte Chemie, EarlyView.
Multiphase DNA–RNA artificial cells integrate a protective DNA shell, a transcriptionally active DNA core, and a functional RNA organelle. Spatial compartmentalization enables signal generation, external protein expression, and selective recapture via RNA aptamers. ABSTRACT Naturally occurring biomolecular condensates orchestrate key cellular processes
Maria Vonk‐de Roy, Daniel Hoenders, Laia Civit, Julián Valero, Andreas Walther   +4 more
wiley   +2 more sources

On the interaction between gold and silver metal atoms and DNA/RNA nucleobases – a comprehensive computational study of ground state properties

Nanotechnology Reviews, 2015
The interaction between metal atoms and nucleobases has been a topic of high interest due to the wide scientific and technological implications. Combining density functional theory simulations with a literature overview, we achieved an exhaustive study ...
Espinosa Leal Leonardo Andres, Lopez-Acevedo Olga   +1 more
doaj   +1 more source