Results 31 to 40 of about 84,247 (263)

The Coronavirus Nucleocapsid Protein [PDF]

, 1995
The nucleocapsid (N) proteins of coronaviruses, as with most enveloped viruses, have received less attention than the surface glycoproteins and generally have been perceived to be of lesser concern. Interest in this class of proteins, however, has been stimulated in recent years by such diverse developments as the recognition of the importance of RNA ...
Laude, Hubert, Masters, S.P.
openaire   +2 more sources

Assembly and transport of filovirus nucleocapsids

PLOS Pathogens, 2022
Filovirus-infected cells are characterized by typical cytoplasmic inclusion bodies (IBs) located in the perinuclear region. The formation of these IBs is induced mainly by the accumulation of the filoviral nucleoprotein NP, which recruits the other nucleocapsid proteins, the polymerase co-factor VP35, the polymerase L, the transcription factor VP30 and
Olga Dolnik, Stephan Becker
openaire   +3 more sources

Identification of (20R)-protopanaxadiol from Panax ginseng as a novel anti-SARS-CoV-2 compound. [PDF]

FEBS Open Bio
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Takeda M, Maezono N, Uchikoshi R, Kato N, Ikeda M.   +4 more
europepmc   +2 more sources

Hantavirus Nucleocapsid Protein Oligomerization [PDF]

Journal of Virology, 2001
ABSTRACT Hantaviruses are enveloped, negative-strand RNA viruses which can be lethal to humans, causing either a hemorrhagic fever with renal syndrome or a hantaviral pulmonary syndrome. The viral genomes consist of three RNA segments: the L segment encodes the viral polymerase, the M segment encodes the viral surface glycoproteins G1 and G2,
A, Alfadhli, Z, Love, B, Arvidson, J, Seeds, J, Willey, E, Barklis   +5 more
openaire   +2 more sources

Au(iii) compounds as HIV nucleocapsid protein (NCp7)–nucleic acid antagonists [PDF]

, 2017
The HIV nucleocapsid NCp7-SL2 RNA interaction is interrupted in the presence of a formally substitution-inert gold(dien)-nucleobase/N-heterocycle AuN4 compound where the N-heterocycle serves the dual purposes of a template for "non-covalent" molecular ...
Fabris, Daniele, Spell, Sarah R, Mangrum, John B, Peterson, Erica J, Ptak, Roger, Farrell, Nicholas P   +5 more
core   +1 more source

Nucleocapsid (N) gene positivity by sample types.

, 2022
Nucleocapsid (N) gene positivity by sample types.
Hendri Marinda Sari (13961334), Dwi Astuti Dharma Putri (13816597), Julie E. Bines (2314435), David T. McCarthy (7848294), Indah K. Murni (8980769), Titik Nuryastuti (9663418), Jarir At Thobari (7134788), Ida Safitri Laksono (13961337), Vicka Oktaria (9461953), Amanda Handley (459772), Endah Supriyati (8727684), Celeste M. Donato (11556184)   +11 more
core   +1 more source

Function of a retrotransposon nucleocapsid protein [PDF]

RNA Biology, 2010
Long terminal repeat (LTR) retrotransposons are not only the ancient predecessors of retroviruses, but they constitute significant fractions of the genomes of many eukaryotic species. Studies of their structure and function are motivated by opportunities to gain insight into common functions of retroviruses and retrotransposons, diverse mechanisms of ...
Sandmeyer, Suzanne B, Clemens, Kristina A   +1 more
openaire   +4 more sources

Partial Functional Rescue of Helicoverpa armigera Single Nucleocapsid Nucleopolyhedrovirus Infectivity by Replacement of F Protein with GP64 from Autographa californica Multicapsid Nucleopolyhedrovirus [PDF]

, 2010
Two distinct envelope fusion proteins (EFPs) (GP64 and F) have been identified in members of the Baculoviridae family of viruses. F proteins are found in group II nucleopolyhedroviruses (NPVs) of alphabaculoviruses and in beta- and deltabaculoviruses ...
Feifei Yin, Shu Shen, Just M. Vlak, Fei Deng, Shen, S., Vlak, J.M., Deng, F., Manli Wang, Ying Tan, Yin, F.F., Hu, Z.H., Wang, M.L., Hualin Wang, Zhihong Hu, Tan, Y., Wang, H.L.   +15 more
core   +1 more source

Evaluation of Diagnostic Performance of Three Indirect Enzyme-Linked Immunosorbent Assays for the Detection of IgG Antibodies to Ebola Virus in Human Sera

Viruses, 2019
Filovirus serological diagnosis and epidemiological investigations are hampered due to the unavailability of validated immunoassays. Diagnostic performance of three indirect enzyme-linked immunosorbent assays (I-ELISA) was evaluated for the detection of ...
Janusz T. Paweska, Naazneen Moolla, Nadia Storm, Veerle Msimang, Ousman Conteh, Jacqueline Weyer, Petrus Jansen van Vuren   +6 more
doaj   +1 more source

Potential Drug Candidates in Clinical Trials for the Treatment of Covid-19: An Updated Overview

Orbital: The Electronic Journal of Chemistry, 2021
The coronavirus (SARS-CoV-2) emerged in December 2019 in Wuhan, China and by the end of April 2020, it spread to more than 200 countries worldwide. Particularly the USA, Brazil, Spain, Italy, France, Germany, UK, Turkey, Iran, and Russia were the most ...
Osmar Ignacio Ayala Cáceres, Fernanda Timóteo, Kristiane Fanti Del Pino Santos, Rafael Rodrigo Piva Vasconcelos, Marco Antonio Utrera Martines, Juliana Jorge, Haroon ur Rashid   +6 more
doaj   +1 more source