Results 31 to 40 of about 82,632 (214)

Anti-spike, Anti-nucleocapsid and Neutralizing Antibodies in SARS-CoV-2 Inpatients and Asymptomatic Individuals

Frontiers in Microbiology, 2020
A better understanding of the anti-SARS-CoV-2 immune response is necessary to finely evaluate commercial serological assays but also to predict protection against reinfection and to help the development of vaccines. For this reason, we monitored the anti-
Etienne Brochot, Etienne Brochot, Baptiste Demey, Baptiste Demey, Antoine Touzé, Sandrine Belouzard, Jean Dubuisson, Jean-Luc Schmit, Jean-Luc Schmit, Gilles Duverlie, Gilles Duverlie, Catherine Francois, Catherine Francois, Sandrine Castelain, Sandrine Castelain, Francois Helle   +15 more
doaj   +1 more source

Drug Repurposing Commonly Against Dengue Virus Capsid and SARS-CoV-2 Nucleocapsid: An in Silico Approach [PDF]

, 2020
In the middle of SARS-CoV-2 pandemic, dengue virus (DENV) is giving a silent warning as the season approaches nearer. There is no specific antiviral against DENV for use in the clinics.
Rupesh, Roy, UPASANA, RAY, Debica, Mukherjee   +2 more
core   +1 more source

Improved control of SARS-CoV-2 by treatment with nucleocapsid-specific monoclonal antibody [PDF]

, 2022
The SARS-CoV-2 spike protein is the main antigen in all approved COVID-19 vaccines and is also the only target for monoclonal antibody therapies. Immune responses to other viral antigens are generated after SARS-CoV-2 infection, but their contribution to
Michelle Richner, Dangi, Tanushree, Pablo Penaloza-MacMaster, Igor J. Koralnik, Young Rock Chung, Visvabharathy, Lavanya, Richner, Michelle C., Bentley, Kirsten, Lavanya Visvabharathy, Richner, Justin M., Richner, Michelle, Penaloza-MacMaster, Pablo, Richard J. Stanton, Chung, Young Rock, Kirsten Bentley, Class, Jacob, Stanton, Richard J., Sarah Sanchez, Sanchez, Sarah, Koralnik, Igor J., Tanushree Dangi, Justin M. Richner, Jacob Class   +22 more
core   +1 more source

Shell Disorder Models Detect That Omicron Has Harder Shells with Attenuation but Is Not a Descendant of the Wuhan-Hu-1 SARS-CoV-2

Biomolecules, 2022
Before the SARS-CoV-2 Omicron variant emergence, shell disorder models (SDM) suggested that an attenuated precursor from pangolins may have entered humans in 2017 or earlier.
Gerard Kian-Meng Goh, A. Keith Dunker, James A. Foster, Vladimir N. Uversky   +3 more
doaj   +1 more source

Characterization and phylogenetic analysis of the chitinase gene from the Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus [PDF]

, 2004
A putative chitinase gene was identified within the fragment EcoRI-K of the Helicoverpa armigera single-nucleocapsid nucleopolyhedrovirus (HearNPV, also called HaSNPIV) genome.
Lauzon, H, Chen, XW, Deng, F, Hu, ZH, Chinese Acad Sci, Wuhan Inst Virol, Joint Lab Invertebrate Virol, Wuhan 430071, Peoples R China, Jehle, JA, Peng, HY, Wang, HL, Arif, BM, Wu, D, Hu, ZH   +9 more
core   +1 more source

Serological Detection of SARS-CoV-2 Antibodies in Naturally-Infected Mink and Other Experimentally-Infected Animals

Viruses, 2021
The recent emergence of SARS-CoV-2 in humans from a yet unidentified animal reservoir and the capacity of the virus to naturally infect pets, farmed animals and potentially wild animals has highlighted the need for serological surveillance tools. In this
Francisco J. Berguido, Peter D. Burbelo, Alessio Bortolami, Francesco Bonfante, Kerstin Wernike, Donata Hoffmann, Anne Balkema-Buschmann, Martin Beer, William G. Dundon, Charles E. Lamien, Giovanni Cattoli   +10 more
doaj   +1 more source

Expanding COVID-19 Vaccine Availability: Role for Combined Orthogonal Serology Testing (COST)

Vaccines, 2021
Background: The persisting Coronavirus disease 2019 (COVID-19) pandemic and limited vaccine supply has led to a shift in global health priorities to expand vaccine coverage.
Madhusudhanan Narasimhan, Lenin Mahimainathan, Ellen Araj, Andrew E Clark, Kathleen Wilkinson, Sruthi Yekkaluri, Jasmin Tiro, Francesca M Lee, Jyoti Balani, Ravi Sarode, Amit G Singal, Alagarraju Muthukumar   +11 more
doaj   +1 more source

Safety and Immunogenicity of the Convacell^® Recombinant N Protein COVID-19 Vaccine

Vaccines
We have developed Convacell®—a COVID-19 vaccine based on the recombinant nucleocapsid (N) protein of SARS-CoV-2. This paper details Convacell’s® combined phase I/II and IIb randomized, double-blind, interventional clinical trials.
Sevastyan Rabdano, Ellina Ruzanova, Denis Makarov, Anastasiya Vertyachikh, Valeriya Teplykh, German Rudakov, Iuliia Pletyukhina, Nikita Saveliev, Konstantin Zakharov, Diana Alpenidze, Vasiliy Vasilyuk, Sergei Arakelov, Veronika Skvortsova   +12 more
doaj   +1 more source

Quantitative measurement of IgG to SARS‐CoV‐2 antigens using monoclonal antibody‐based enzyme‐linked immunosorbent assays

Clinical & Translational Immunology, 2022
Objective Standardised quantitative analysis of the humoral immune response to SARS‐CoV‐2 antigens may be useful for estimating the extent and duration of immunity. The aim was to develop enzyme‐linked immunosorbent assays (ELISAs) for the quantification
Ingrid Sander, Sabine Kespohl, Eva Zahradnik, Philipp Göcke, Ingolf Hosbach, Burkhard L Herrmann, Thomas Brüning, Monika Raulf   +7 more
doaj   +1 more source

Specificity of Baculorivus P6.9 Basic DNA-Binding Proteins and Critical Role of the C Terminus in Virion Formation [PDF]

, 2010
The majority of double-stranded DNA (dsDNA) viruses infecting eukaryotic organisms use host- or virus-expressed histones or protamine-like proteins to condense their genomes.
Wang, Hualin, Tuladhar, Era, Shu Shen, Just M. Vlak, Wang, Manli, Shen, S., van Oers, M.M., Wang, H., Monique M. van Oers, Vlak, J.M., Manli Wang, Westenberg, Marcel, van Oers, Monique M., Wang, M., Tuladhar, E., Marcel Westenberg, Westenberg, M., Vlak, Just M., Hualin Wang, Oers, M.M., van, Shen, Shu, Era Tuladhar   +21 more
core   +1 more source