Results 41 to 50 of about 79,219 (253)

Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]

, 2013
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Richard M. Elliott, Böttcher, Bettina, Li, P., Dong, H., Li, Ping, Dong, Changjiang, Dong, Haohao, Elliott, R., Boettcher, Bettina, Elliott, Richard M., Bottcher, B., Haohao Dong, Bettina Böttcher, Ping Li, Elliott, Richard M, Dong, C., Changjiang Dong   +16 more
core   +1 more source

Evaluation of Diagnostic Performance of Three Indirect Enzyme-Linked Immunosorbent Assays for the Detection of IgG Antibodies to Ebola Virus in Human Sera

Viruses, 2019
Filovirus serological diagnosis and epidemiological investigations are hampered due to the unavailability of validated immunoassays. Diagnostic performance of three indirect enzyme-linked immunosorbent assays (I-ELISA) was evaluated for the detection of ...
Janusz T. Paweska, Naazneen Moolla, Nadia Storm, Veerle Msimang, Ousman Conteh, Jacqueline Weyer, Petrus Jansen van Vuren   +6 more
doaj   +1 more source

Characterization and phylogenetic analysis of the chitinase gene from the Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus [PDF]

, 2004
A putative chitinase gene was identified within the fragment EcoRI-K of the Helicoverpa armigera single-nucleocapsid nucleopolyhedrovirus (HearNPV, also called HaSNPIV) genome.
Lauzon, H, Chen, XW, Deng, F, Hu, ZH, Chinese Acad Sci, Wuhan Inst Virol, Joint Lab Invertebrate Virol, Wuhan 430071, Peoples R China, Jehle, JA, Peng, HY, Wang, HL, Arif, BM, Wu, D, Hu, ZH   +9 more
core   +1 more source

Anti-spike, Anti-nucleocapsid and Neutralizing Antibodies in SARS-CoV-2 Inpatients and Asymptomatic Individuals

Frontiers in Microbiology, 2020
A better understanding of the anti-SARS-CoV-2 immune response is necessary to finely evaluate commercial serological assays but also to predict protection against reinfection and to help the development of vaccines. For this reason, we monitored the anti-
Etienne Brochot, Etienne Brochot, Baptiste Demey, Baptiste Demey, Antoine Touzé, Sandrine Belouzard, Jean Dubuisson, Jean-Luc Schmit, Jean-Luc Schmit, Gilles Duverlie, Gilles Duverlie, Catherine Francois, Catherine Francois, Sandrine Castelain, Sandrine Castelain, Francois Helle   +15 more
doaj   +1 more source

Shell Disorder Models Detect That Omicron Has Harder Shells with Attenuation but Is Not a Descendant of the Wuhan-Hu-1 SARS-CoV-2

Biomolecules, 2022
Before the SARS-CoV-2 Omicron variant emergence, shell disorder models (SDM) suggested that an attenuated precursor from pangolins may have entered humans in 2017 or earlier.
Gerard Kian-Meng Goh, A. Keith Dunker, James A. Foster, Vladimir N. Uversky   +3 more
doaj   +1 more source

Predictors of a positive anti-nucleocapsid IgG result. [PDF]

, 2022
Predictors of a positive anti-nucleocapsid IgG result.
Zahir Moloo (6328796), Anthony Etyang (9145627), Shahin Sayed (6328763), Daniel Maina (2187787), Patrick Mugaine (14020141), Rodney Adam (9946673), Geoffrey Omuse (2187784), George Ong’ete (14020138), Reena Shah (9946679)   +8 more
core   +1 more source

Serological Detection of SARS-CoV-2 Antibodies in Naturally-Infected Mink and Other Experimentally-Infected Animals

Viruses, 2021
The recent emergence of SARS-CoV-2 in humans from a yet unidentified animal reservoir and the capacity of the virus to naturally infect pets, farmed animals and potentially wild animals has highlighted the need for serological surveillance tools. In this
Francisco J. Berguido, Peter D. Burbelo, Alessio Bortolami, Francesco Bonfante, Kerstin Wernike, Donata Hoffmann, Anne Balkema-Buschmann, Martin Beer, William G. Dundon, Charles E. Lamien, Giovanni Cattoli   +10 more
doaj   +1 more source

Role of the nucleocapsid region in HIV-1 Gag assembly as investigated by quantitative fluorescence-based microscopy [PDF]

, 2014
International audienceThe Gag precursor of HIV-1, formed of the four proteic regions matrix (MA), capsid (CA), nucleocapsid (NC) and p6, orchestrates virus morphogenesis.
Didier, Pascal, El Meshri, Salah Edin, Richert, Ludovic, de Rocquigny, Hugues, Mély, Yves, Darlix, Jean-Luc   +5 more
core   +1 more source

Expanding COVID-19 Vaccine Availability: Role for Combined Orthogonal Serology Testing (COST)

Vaccines, 2021
Background: The persisting Coronavirus disease 2019 (COVID-19) pandemic and limited vaccine supply has led to a shift in global health priorities to expand vaccine coverage.
Madhusudhanan Narasimhan, Lenin Mahimainathan, Ellen Araj, Andrew E Clark, Kathleen Wilkinson, Sruthi Yekkaluri, Jasmin Tiro, Francesca M Lee, Jyoti Balani, Ravi Sarode, Amit G Singal, Alagarraju Muthukumar   +11 more
doaj   +1 more source

Safety and Immunogenicity of the Convacell^® Recombinant N Protein COVID-19 Vaccine

Vaccines
We have developed Convacell®—a COVID-19 vaccine based on the recombinant nucleocapsid (N) protein of SARS-CoV-2. This paper details Convacell’s® combined phase I/II and IIb randomized, double-blind, interventional clinical trials.
Sevastyan Rabdano, Ellina Ruzanova, Denis Makarov, Anastasiya Vertyachikh, Valeriya Teplykh, German Rudakov, Iuliia Pletyukhina, Nikita Saveliev, Konstantin Zakharov, Diana Alpenidze, Vasiliy Vasilyuk, Sergei Arakelov, Veronika Skvortsova   +12 more
doaj   +1 more source