Results 41 to 50 of about 105,644 (246)
Mouse Hepatitis Coronavirus Nucleocapsid Phosphorylation [PDF]
The coronavirus nucleocapsid (N) is a multifunctional phosphoprotein that encapsidates the genomic RNA into a helical nucleocapsid within the mature virion. The protein also plays roles in viral RNA transcription and/or replication and possibly viral mRNA translation.
White, Tiana C., Hogue, Brenda G.
openaire +2 more sources
Safety and Immunogenicity of the Convacell® Recombinant N Protein COVID-19 Vaccine
We have developed Convacell®—a COVID-19 vaccine based on the recombinant nucleocapsid (N) protein of SARS-CoV-2. This paper details Convacell’s® combined phase I/II and IIb randomized, double-blind, interventional clinical trials.
Sevastyan Rabdano +12 more
doaj +1 more source
Vaccination is one of the best ways to control the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic. Among the various SARS-CoV-2 vaccines approved for use, the BBIBP-CorV inactivated vaccine has been widely used in 93 countries.
Qinjin Wang +9 more
doaj +1 more source
Why enveloped viruses need cores -- the contribution of a nucleocapsid core to viral budding
During the alphavirus lifecycle, a nucleocapsid core buds through the cell membrane to acquire an outer envelope of lipid membrane and viral glycoproteins. However, the presence of a nucleocapsid core is not required for assembly of infectious particles.
Hagan, Michael F. +2 more
core +1 more source
Development of an experimental inactivated PRRSV vaccine that induces virus-neutralizing antibodies [PDF]
Porcine reproductive and respiratory syndrome virus (PRRSV) can induce reproductive disorders and is involved in the porcine respiratory disease complex, causing tremendous economic losses to the swine industry.
Delputte, Peter +4 more
core +3 more sources
Hematopoietic cell transplantation (HCT) and chimeric antigen receptor (CAR)-T cell patients are immunocompromised, remain at high risk following SARS-CoV-2 infection, and are less likely than immunocompetent individuals to respond to vaccination.
Flavia Chiuppesi +36 more
doaj +1 more source
Conformational spread as a mechanism for cooperativity in the bacterial flagellar switch [PDF]
The bacterial flagellar switch that controls the direction of flagellar rotation during chemotaxis has a highly cooperative response. This has previously been understood in terms of the classic two-state, concerted model of allosteric regulation.
F. Bai +29 more
core +3 more sources
The Nucleocapsid of Berne Virus
In Berne virus-infected cells and in gradient-purified virions two major proteins with mol. wt. of 20K and 22K were detected. The 22K species is thought to represent the main envelope polypeptide; in infectious culture media it was present in a low envelope polypeptide; in infectious culture media it was present in a low density substructure which ...
Horzinek, M.C. +2 more
openaire +3 more sources
Background: Long COVID is a condition characterized by long-term sequelae persisting after the typical convalescence period of COVID-19. Previous reports have suggested the role of an unsatisfactory immune response and impaired viral clearance in the ...
Reka Varnai +6 more
doaj +1 more source
A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]
Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Bernadet, Philippe +14 more
core +2 more sources

