Results 21 to 30 of about 84,247 (263)

Time-Resolved Fluorescence Investigation of the Human Immunodeficiency Virus Type 1 Nucleocapsid Protein: Influence of the Binding of Nucleic Acids [PDF]

, 1999
Depending on the HIV-1 isolate, MN or BH10, the nucleocapsid protein, NCp7, corresponds to a 55- or 71-amino acid length product, respectively. The MN NCp7 contains a single Trp residue at position 37 in the distal zinc finger motif, and the BH10 NCp7 ...
Piemont, Etienne, Constance Vuilleumier, Etienne Piémont, Gerard, Dominique, Roques, Bernard P., Ababou, Abdessamad, Mely, Yves, Yves Mély, Bombarda, Elisa, Dominique Gérard, Bernard P. Roques, Abdessamad Ababou, Vuilleumier, Constance, Elisa Bombarda   +13 more
core   +1 more source

Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization [PDF]

, 2013
All orthobunyaviruses possess three genome segments of single-stranded negative sense RNA that are encapsidated with the virus-encoded nucleocapsid (N) protein to form a ribonucleoprotein (RNP) complex, which is uncharacterized at high resolution.
Stonehouse, N. J., Ranson, N. A., Hiscox, JA, Matthews, SV, Walter, C. T., Hiscox, J. A., Fooks, Anthony R., Walter, Cheryl T., Shepherd, DA, Ariza, Antonio, Shepherd, D. A., Elliott, R.M., Fooks, AR, Hiscox, Julian A., Dent, KC, Barr, John N., Edwards, T. A., Tanner, SJ, Dent, Kyle C., Matthews, S. V., Shepherd, D.A., Stonehouse, N.J., Barr, J. N., Dent, K.C., Barr, JN, Stonehouse, NJ, Hiscox, J.A., Tanner, S. J., Edwards, T.A., Stonehouse, Nicola J., Dent, K. C., Luo, Ming, Ashcroft, A.E., Shepherd, Dale A., Green, T. J., Ariza, A, Elliott, RM, Elliott, Richard M., Tanner, S.J., Tanner, Sian J., Ariza, A., Wu, W., Edwards, Thomas A., Matthews, Susan V., Ashcroft, Alison E., Wu, W, Green, Todd J., Green, TJ, Walter, C.T., Fooks, A. R., Fooks, A.R., Luo, M, Ashcroft, A. E., Ranson, Neil A., Luo, M., Walter, CT, Elliott, R. M., Green, T.J., Matthews, S.V., Ranson, N.A., Barr, J.N., Ashcroft, AE, Edwards, TA, Ranson, NA, Wu, Weining   +64 more
core   +1 more source

Form-determining functions in Sindbis virus nucleocapsids: nucleosomelike organization of the nucleocapsid [PDF]

Journal of Virology, 1989
Purified intact Sindbis virus nucleocapsids were treated at different pH values or with various concentrations of divalent cations, cation chelators, salt, or formamide. The resulting structures were examined by velocity sedimentation, electron microscopy, and protein-protein cross-linking.
K M, Coombs, D T, Brown
openaire   +2 more sources

Serodominant SARS-CoV-2 Nucleocapsid Peptides Map to Unstructured Protein Regions

Microbiology Spectrum, 2023
The SARS-CoV-2 nucleocapsid (N) protein is highly immunogenic, and anti-N antibodies are commonly used as markers for prior infection. While several studies have examined or predicted the antigenic regions of N, these have lacked consensus and structural
Jacob P. Vandervaart, Nicole L. Inniss, Ted Ling-Hu, George Minasov, Grant Wiersum, Monica Rosas-Lemus, Ludmilla Shuvalova, Chad J. Achenbach, Judd F. Hultquist, Karla J. F. Satchell, Kelly E. R. Bachta   +10 more
doaj   +1 more source

The Nucleocapsid of Berne Virus

Journal of General Virology, 1985
In Berne virus-infected cells and in gradient-purified virions two major proteins with mol. wt. of 20K and 22K were detected. The 22K species is thought to represent the main envelope polypeptide; in infectious culture media it was present in a low envelope polypeptide; in infectious culture media it was present in a low density substructure which ...
Horzinek, M.C., Ederveen, J., Weiss, Marianne   +2 more
openaire   +3 more sources

Baculovirus AC102 is a nucleocapsid protein that is crucial for nuclear actin polymerization and nucleocapsid morphogenesis [PDF]

Journal of Virology, 2018
ABSTRACT The baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV), the type species of alphabaculoviruses, is an enveloped DNA virus that infects lepidopteran insects and is commonly known as a vector for protein expression and cell transduction.
Hepp, Susan E., Borgo, Gina M., Ticau, Simina, Ohkawa, Taro, Welch, Matthew D.   +4 more
openaire   +4 more sources

Cryo-EM analysis of Ebola virus nucleocapsid-like assembly [PDF]

, 2022
This protocol describes the reconstitution of the filamentous Ebola virus nucleocapsid-like ...
Amarasinghe, Gaya K, Pintilie, Grigore D, Gaya K. Amarasinghe, Chiu, Wah, Wah Chiu, Wang, Yan, Zhaoming Su, Daisy W. Leung, Binning, Jennifer M, Su, Zhaoming, Yan Wang, Jennifer M. Binning, Grigore D. Pintilie, Leung, Daisy W   +13 more
core   +1 more source

Functional analysis of the orthobunyavirus nucleocapsid (N) protein [PDF]

, 2008
Bunyamwera virus (BUNV) is the prototype of the family Bunyaviridae. It has a tripartite genome consisting of negative sense RNA segments called large (L), medium (M) and small (S). The S segment encodes the nucleocapsid protein (N) of 233 amino acids.
Eifan, Saleh A.
core   +2 more sources

The A, B, Cs of Herpesvirus Capsids

Viruses, 2015
Assembly of herpesvirus nucleocapsids shares significant similarities with the assembly of tailed dsDNA bacteriophages; however, important differences exist.
Ritesh Tandon, Edward S. Mocarski, James F. Conway   +2 more
doaj   +1 more source

SARS-CoV-2 Nucleocapsid Protein Interacts with RIG-I and Represses RIG-Mediated IFN-β Production

Viruses, 2020
SARS-CoV-2 is highly pathogenic in humans and poses a great threat to public health worldwide. Clinical data shows a disturbed type I interferon (IFN) response during the virus infection.
Keli Chen, Feng Xiao, Dingwen Hu, Weiwei Ge, Mingfu Tian, Wenbiao Wang, Pan Pan, Kailang Wu, Jianguo Wu   +8 more
doaj   +1 more source