Results 21 to 30 of about 69,939 (210)
The Nucleocapsid of Berne Virus
Journal of General Virology, 1985 In Berne virus-infected cells and in gradient-purified virions two major proteins with mol. wt. of 20K and 22K were detected. The 22K species is thought to represent the main envelope polypeptide; in infectious culture media it was present in a low envelope polypeptide; in infectious culture media it was present in a low density substructure which ...
Horzinek, M.C. +2 more
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Alphavirus Nucleocapsid Packaging and Assembly [PDF]
Viruses, 2018 Alphavirus nucleocapsids are assembled in the cytoplasm of infected cells from 240 copies of the capsid protein and the approximately 11 kb positive strand genomic RNA. However, the challenge of how the capsid specifically selects its RNA package and assembles around it has remained an elusive one to solve.
Adriano Mendes, Richard J. Kuhn
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Hantavirus Nucleocapsid Protein Oligomerization [PDF]
Journal of Virology, 2001 ABSTRACT Hantaviruses are enveloped, negative-strand RNA viruses which can be lethal to humans, causing either a hemorrhagic fever with renal syndrome or a hantaviral pulmonary syndrome. The viral genomes consist of three RNA segments: the L segment encodes the viral polymerase, the M segment encodes the viral surface glycoproteins G1 and G2,
A, Alfadhli +5 more
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Assembly and transport of filovirus nucleocapsids
PLOS Pathogens, 2022 Filovirus-infected cells are characterized by typical cytoplasmic inclusion bodies (IBs) located in the perinuclear region. The formation of these IBs is induced mainly by the accumulation of the filoviral nucleoprotein NP, which recruits the other nucleocapsid proteins, the polymerase co-factor VP35, the polymerase L, the transcription factor VP30 and
Olga Dolnik, Stephan Becker
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Potential Drug Candidates in Clinical Trials for the Treatment of Covid-19: An Updated Overview
Orbital: The Electronic Journal of Chemistry, 2021 The coronavirus (SARS-CoV-2) emerged in December 2019 in Wuhan, China and by the end of April 2020, it spread to more than 200 countries worldwide. Particularly the USA, Brazil, Spain, Italy, France, Germany, UK, Turkey, Iran, and Russia were the most ...
Osmar Ignacio Ayala Cáceres +6 more
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Function of a retrotransposon nucleocapsid protein [PDF]
RNA Biology, 2010 Long terminal repeat (LTR) retrotransposons are not only the ancient predecessors of retroviruses, but they constitute significant fractions of the genomes of many eukaryotic species. Studies of their structure and function are motivated by opportunities to gain insight into common functions of retroviruses and retrotransposons, diverse mechanisms of ...
Sandmeyer, Suzanne B +1 more
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Viruses, 2019 Filovirus serological diagnosis and epidemiological investigations are hampered due to the unavailability of validated immunoassays. Diagnostic performance of three indirect enzyme-linked immunosorbent assays (I-ELISA) was evaluated for the detection of ...
Janusz T. Paweska +6 more
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Frontiers in Microbiology, 2020 A better understanding of the anti-SARS-CoV-2 immune response is necessary to finely evaluate commercial serological assays but also to predict protection against reinfection and to help the development of vaccines. For this reason, we monitored the anti-
Etienne Brochot +15 more
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Biomolecules, 2022 Before the SARS-CoV-2 Omicron variant emergence, shell disorder models (SDM) suggested that an attenuated precursor from pangolins may have entered humans in 2017 or earlier.
Gerard Kian-Meng Goh +3 more
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Viruses, 2021 The recent emergence of SARS-CoV-2 in humans from a yet unidentified animal reservoir and the capacity of the virus to naturally infect pets, farmed animals and potentially wild animals has highlighted the need for serological surveillance tools. In this
Francisco J. Berguido +10 more
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