Results 101 to 110 of about 3,660,966 (235)

Nucleocapsid protein gene of Junin arenavirus (cDNA sequence) [PDF]

open access: yes, 1989
The Arenavirus S RNA codes for the major structural polypeptides: the nucleocapsid protein, N, and the glycoproteins Gl and G2, that are derived from an intracellular precursor protein, GPC. We have cloned and sequenced the entire coding region for the N
Ghiringhelli, Daniel   +5 more
core   +1 more source

SARS coronavirus: Unusual lability of the nucleocapsid protein

open access: yesBiochemical and Biophysical Research Communications, 2008
The severe acute respiratory syndrome (SARS) is a contagious disease that killed hundreds and sickened thousands of people worldwide between November 2002 and July 2003. The nucleocapsid (N) protein of the coronavirus responsible for this disease plays a critical role in viral assembly and maturation and is of particular interest because of its ...
Mark, John   +5 more
openaire   +2 more sources

Modular characterization of SARS-CoV-2 nucleocapsid protein domain functions in nucleocapsid-like assembly

open access: yesMolecular Biomedicine, 2023
SARS-CoV-2 and its variants, with the Omicron subvariant XBB currently prevailing the global infections, continue to pose threats on public health worldwide. This non-segmented positive-stranded RNA virus encodes the multi-functional nucleocapsid protein
Yan Wang   +16 more
doaj   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

open access: yesBiological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad   +5 more
wiley   +1 more source

Inhibition of Endosomal Transport Results in Decreased Synthesis of Nucleocapsid Protein of PHV Virus [PDF]

open access: yesУчёные записки Казанского университета: Серия Естественные науки, 2017
This paper is devoted to investigation of molecular mechanisms of transport of nucleocapsid protein of non-pathogenic virus Prospect Hill. Prospect Hill virus (PHV) belongs to the family Bunyaviridae, genus Hantavirus.
M. Muyangwa, E.E. Garanina
doaj  

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

open access: yesElectron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary   +5 more
wiley   +1 more source

Nucleocapsid protein gene of Junin arenavirus (cDNA sequence) [PDF]

open access: yes, 2021
The Arenavirus S RNA codes for the major structural polypeptides: the nucleocapsid protein, N, and the glycoproteins Gl and G2, that are derived from an intracellular precursor protein, GPC. We have cloned and sequenced the entire coding region for the N
Ghiringhelli, Daniel   +5 more
core  

Background Paper Functions of the Coronavirus Nucleocapsid Protein [PDF]

open access: yes, 1990
In 1962 Caspar and Klug conjectured that self-assembly of equivalent or quasi-equivalent protein subunits and viral nucleic acid produces either icosahedral or helical structures according to the biological functions required (1). Some 15 years later Wengler introduced the terms “transcription helices” and “translation helices” to describe the ...
P S, Masters, L S, Sturman
openaire   +2 more sources

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

open access: yesFlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu   +3 more
wiley   +1 more source

Confirmation of the Specificity of the Monoclonal Antibody 4D11 for the SARS-CoV Nucleocapsid Protein

open access: yes, 2013
SARS-CoV immunohistochemical staining of 293T cells transfected with spike (S), nucleocapsid (N), and spike, nucleocapsid, membrane, and envelope (SEMN) genes of SARS-CoV. Untransfected control is shown in the lower right photomicrograph.
Kwok H Chan (61037)   +7 more
core   +1 more source

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