Results 151 to 160 of about 3,660,966 (235)

Hitting Coronaviruses Where It Hurts: Antiviral Strategies Targeting Viral Proteins

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
Viral proteins represent key vulnerabilities in human coronaviruses (HCoVs). This review outlines inhibitors targeting spike (S), main protease (Mpro), papain‐like protease (PLpro), and RNA‐dependent RNA polymerase (RdRp), mapping chemically diverse strategies that disrupt entry and replication, and provides an integrated view of current candidates ...
Álvaro de la Cruz‐Potenciano, Miguel Maldonado, María‐José Camarasa, Sonia de Castro   +3 more
wiley   +1 more source

Bovine Coronavirus Nucleocapsid Protein Processing and Assembly [PDF]

, 1995
The coronavirus nucleocapsid protein (N) encapsidates the genomic RNA to form a helical nucleocapsid. The requirements for coronavirus nucleocapsid assembly are being studied. Two forms (approximately 50 kDa and 55 kDa) of the bovine coronavirus (BCV) N protein were detected in infected cells.
openaire   +2 more sources

The recombinant nucleocapsid protein of Newcastle disease virus produced in yeast.

, 2010
This invention provides the recombinant nucleocapsid protein of the Malaysian velogenic Newcastle disease virus strain AF2240. The invention relates to methods for producing recombinant nucleocapsid protein in a eukaryotic expression system, in ...
Sekawi, Zamberi, Jahanshiri, Fatemeh, Saidin, Syswan, Mohd. Yusoff, Khatijah, Jalilian, Farid Azizi   +4 more
core   +1 more source

Nucleocapsid Protein [PDF]

, 2020
openaire   +1 more source

Zinc-binding properties of Junín virus nucleocapsid protein [PDF]

, 2019
The arenavirus nucleocapsid protein (N) is a highly basic 63 kDa protein with a dual function during the virus life-cycle. First, it is involved in essential steps of genome replication, promoting the synthesis of the full-length antigenomic copy of S ...
Ghiringhelli, P. D., Lozano, Mario E., Albariño, César G., Romanowski, Víctor, Tortorici, María Alejandra   +4 more
core  

Studies on the nucleocapsid protein of infectious bronchitis virus [PDF]

, 2005
Because phosphorylation of the infectious bronchitis virus (IBV) nucleocapsid (N) protein may regulate its multiple roles in viral replication, the dynamics of N phosphorylation were examined.
Jayaram, Jyothi
core  

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Nature Communications
Viruses, as opportunistic intracellular parasites, hijack the cellular machinery of host cells to support their survival and propagation. Numerous viral proteins are subjected to host-mediated post-translational modifications.
Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang   +11 more
doaj   +1 more source

A method for purifying the nucleocapsid protein of Nipah virus.

, 2009
The present invention provides a method to purify a recombinant protein from microbial cell immobilized metal affinity chromatography. The method leads to the recovery of the nucleocapsid of Nipah virus in high yields, biologically active and free from ...
Tan, Weng Siang, Tey, Beng Ti, Chong, Fui Chin   +2 more
core   +1 more source

The role of the nucleocapsid serine proteinase in the formation of the Sindbis virus nucleocapsid protein

, 1998
The Sindbis virus (SINV) nucleocapsid protein (NCP) is a 264 amino acid protein that is involved in a variety of functions in the virus life cycle. In addition to its role as a viral structural protein and an RNA-binding protein, the NCP is also a serine
Little, Carla Norrene
core   +1 more source

SARS-CoV-2 nucleocapsid protein hijacks host transcription by targeting eEF1A1. [PDF]

Life Sci Alliance
Bidon B, Lai YL, Chao TL, Chen G, Lee YS, Huang HH, Chen JS, Gonzalez Losada A, Chang SY, Egly JM, Li TK.   +10 more
europepmc   +1 more source