Results 51 to 60 of about 3,660,966 (235)

Severe acute respiratory syndrome coronavirus nucleocapsid protein does not modulate transcription of the human FGL2 gene [PDF]

, 2009
Among the structural and nonstructural proteins of severe acute respiratory syndrome coronavirus (SARS-CoV), the nucleocapsid (N) protein plays pivotal roles in the biology and pathogenesis of viral infection.
Siu, KL, Jin, DY, Chan, CP, Chan, C, Zheng, BJ   +4 more
core   +1 more source

Measles virus nucleocapsid protein expressed in insect cells assembles into nucleocapsid-like structures

Journal of General Virology, 1993
The gene encoding the major nucleocapsid, N, protein of measles virus has been inserted into a baculovirus vector under the control of the polyhedrin promoter. Insect cells infected with this recombinant baculovirus synthesize high levels of measles N protein, up to 40% of total soluble cell protein.
A R, Fooks, J R, Stephenson, A, Warnes, A B, Dowsett, B K, Rima, G W, Wilkinson   +5 more
openaire   +2 more sources

Nucleocapsid as a next-generation COVID-19 vaccine candidate

International Journal of Infectious Diseases, 2022
Multiple new variants of the SARS-CoV-2 virus have emerged globally, due to viral mutation. The majority of COVID-19 vaccines contain SARS-CoV-2 spike protein, which is susceptible to mutation. It is known that protection against COVID-19 after two doses
Bryan Oronsky, Christopher Larson, Scott Caroen, Farah Hedjran, Ana Sanchez, Elena Prokopenko, Tony Reid   +6 more
doaj   +1 more source

The nucleocapsid protein gene of bovine coronavirus is bicistronic [PDF]

Journal of Virology, 1992
For animal RNA viruses that replicate through an RNA intermediate, reported examples of bicistronic mRNAs with overlapping open reading frames in which one cistron is contained entirely within another have been made only for those with negative-strand or double-stranded genomes.
S D, Senanayake, M A, Hofmann, J L, Maki, D A, Brian   +3 more
openaire   +2 more sources

Age- and sex-based changes in spike protein antibody status after SARS-CoV-2 vaccination and effect of past-infection in healthcare workers in Osaka

BMC Infectious Diseases, 2022
Objective We aimed to compare the changes in SARS-CoV-2 spike protein antibody titres based on age group and sex using paired blood sampling after vaccination in association with the presence of nucleocapsid protein antibody.
Shiro Hoshida, Nobuyuki Koeda, Hideki Hattori, Masahiro Tanaka, Ichiro Tanaka, Hiroyuki Fukui, Junya Fujita, Yo Sasaki, Shigeyuki Tamura   +8 more
doaj   +1 more source

Detection of Anti-Nucleocapsid Antibody in COVID-19 Patients in Bangladesh Is not Correlated with Previous Dengue Infection

Pathogens, 2021
Background: The assessment of antibody responses to severe acute respiratory syndrome coronavirus-2 is potentially confounded by exposures to flaviviruses. The aims of the present research were to determine whether anti-dengue antibodies affect the viral
Simon D. Lytton, Mahmuda Yeasmin, Asish Kumar Ghosh, Md. Rakibul Hassan Bulbul, Md. Maruf Ahmed Molla, Martha Herr, Helmut Duchmann, Md. Mohiuddin Sharif, Tasnim Nafisa, Md. Robed Amin, Nur Hosen, Md. Tanvir Rahman, Sumaiya Islam, Alimul Islam, Abul Khair Mohammad Shamsuzzaman   +14 more
doaj   +1 more source

The SARS-CoV nucleocapsid protein: A protein with multifarious activities

Infection, Genetics and Evolution, 2008
Ever since the discovery of SARS-CoV in the year 2003, numerous researchers around the world have been working relentlessly to understand the biology of this virus. As in other coronaviruses, nucleocapsid (N) is one of the most crucial structural components of the SARS-CoV.
Surjit, Milan, Lal, Sunil K.
openaire   +2 more sources

Hantavirus Nucleocapsid Protein Coiled-Coil Domains [PDF]

Journal of Biological Chemistry, 2002
The nucleocapsid (N) proteins of hantaviruses such as the Sin Nombre virus (SNV) bind to membranes and viral RNAs, associate with transcription and replication complexes, and oligomerize during the process of virus assembly. N proteins trimerize in vitro and in vivo, and associate via assembly domains at their amino- and carboxyl-terminal ends. Because
Ayna, Alfadhli, Eric, Steel, Liam, Finlay, Hans Peter, Bächinger, Eric, Barklis   +4 more
openaire   +2 more sources

Unleashing Monoclonal Antibodies: Targeting Covid-19’s Nucleocapsid Protein and Spike Antigens [PDF]

Archives of Razi Institute
Since the end of 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected many people globally. Diagnosis and treatment of patients have a pivotal role in surviving them.
Rasool Madani, Fariba Golchinfar, Mahsa Hezarosi, Tara Emami   +3 more
doaj   +1 more source

Homotypic Interaction of Bunyamwera Virus Nucleocapsid Protein [PDF]

Journal of Virology, 2005
ABSTRACT The bunyavirus nucleocapsid protein, N, plays a central role in viral replication in encapsidating the three genomic RNA segments to form functional templates for transcription and replication by the viral RNA-dependent RNA polymerase.
Vincent H J, Leonard, Alain, Kohl, Jane C, Osborne, Angela, McLees, Richard M, Elliott   +4 more
openaire   +2 more sources