Results 111 to 120 of about 12,341 (216)
Nucleolin gene silencing in THP-1 cells.
, 2013 (A) For each experiment, the nucleolin downregulation in the THP-1 by lentiviral gene silencing was checked on protein level 3 and 6 days post infection by Western blotting of whole cell extracts with monoclonal anti-nucleolin antibody (upper panel ...
Inna Dumler (368582) +9 more
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Centrosomal nucleolin is required for microtubule network organization
, 2015 Nucleolin is a pleiotropic protein involved in a variety of cellular processes. Although multipolar spindle formation has been observed after nucleolin depletion, the roles of nucleolin in centrosome regulation and functions have not been addressed. Here
Anne-Marie Tassin (88902) +11 more
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Oncogenic Synergism between ErbB1, Nucleolin, and Mutant Ras
, 2011 Alterations in the ErbB family of growth factor receptors, their signaling components, and mutational activation of Ras proteins are major contributors to malignant transformation. Recently, mutant Ras was shown to be capable of activating ErbB receptors
Adrienne D. Cox +9 more
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Nucleolin interacts with several ribosomal proteins through its RGG domain.
, 1998 Nucleolin is one of the major nonribosomal proteins of the nucleolus. Through its four RNA-binding domains, nucleolin interacts specifically with pre-rRNA as soon as synthesis begins, but it is not found in mature cytoplasmic ribosomes. Nucleolin is able
Madjar, J. J. +4 more
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Nucleolin expression affects microtubule growth.
, 2016 (A)-(C): Box and whisker plots represent tracks for growth speed (A), growth life time (B) and growth displacement (C). For each condition (control [black], nucleolin depletion [dark red], nucleolin over expression [dark blue], B23 depletion [light red ...
Fabien Mongelard (79465) +5 more
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Nucleolin binds the cytoplasmic tail of ErbB4.
, 2013 (A) SDS-PAGE of Coomassie blue–stained proteins isolated from PC12 cell extracts, loaded on GST-ErbB4 agarose affinity matrix or control GST agarose matrix.
Keren Farin (86092) +2 more
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Nucleolin and ErbB1- induced anchorage-independent growth.
, 2013 (A) Rat-1 cells stably expressing empty vector (not shown), ErbB1, nucleolin or ErbB1 and nucleolin were seeded in soft agar (6000 cells/well in 96 well plates) in medium containing 10% FBS, 0.3% agar, in the presence of 100 ng/ml EGF.
Keren Farin (86092) +2 more
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In vitro binding of nucleolin to double-stranded telomeric DNA
We have purified a 100 kDa protein, resolved in a Southwestern binding screen of total nuclear proteins from Hela cells with double-stranded human telomeric probe.
Bilaud, T +5 more
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电离辐射诱导HepG2细胞中Nucleolin和p53变化时程研究
Zhongguo shiyan zhenduanxue, 2013 目的检测电离辐射照射HepG2细胞后,其Nucleolin和p53蛋白的变化情况,结果将为进一步揭示电离辐射对p53信号传导通路的影响提供重要的细胞学基础,并为辐射生物效应研究提供新的生物学依据。方法电离辐射照射HepG2细胞后,分别提取总蛋白、胞浆蛋白和胞核蛋白,然后采用流式和Western Blot的方法进行蛋白检测。结果 HepG2细胞接受4Gy电离辐射照射后,其总蛋白中的Nucleolin和p53表达水平增高,且与照射时间呈正相关;HepG2细胞接受电离辐射照射后的2h ...
钟莉莉 +4 more
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