Results 91 to 100 of about 12,341 (216)

Aberrant expression of CITED2 promotes prostate cancer metastasis by activating the nucleolin-AKT pathway

Nature Communications, 2018
More effective strategies are needed to prevent prostate cancer metastasis. Here they report CBP/p300-interacting transactivator with E/D-rich carboxy-terminal domain-2 (CITED2) to interact with nucleolin, p300, and PRMT5 subunits, and reveal a role of ...
Seung-Hyun Shin, Ga Young Lee, Mingyu Lee, Jengmin Kang, Hyun-Woo Shin, Yang-Sook Chun, Jong-Wan Park   +6 more
doaj   +1 more source

Met-Independent Hepatocyte Growth Factor-mediated regulation of cell adhesion in human prostate cancer cells

BMC Cancer, 2006
Background Prostate cancer cells communicate reciprocally with the stromal cells surrounding them, inside the prostate, and after metastasis, within the bone. Each tissue secretes factors for interpretation by the other.
Davis Rodney, Sikes Robert A, Bradley Michael J, Isotani Shuji, Tate Amanda, Chung Leland WK, Edlund Magnus   +6 more
doaj   +1 more source

Nucleolin functions in nucleolus formation and chromosome congression [PDF]

Ma N., Matsunaga S., Takata H., et al. Nucleolin functions in nucleolus formation and chromosome congression. Journal of Cell Science, 120, 12, 2091. https://doi.org/10.1242/jcs.008771.A complex structure, designated the chromosome periphery, surrounds ...
Matsunaga, Sachihiro, Fukui, Kiichi, Ma, Nan, Ono, Rika, Uchiyama, Susumu, Takata, Hideaki   +5 more
core   +1 more source

A fucose-containing O-glycoepitope on bovine and human nucleolin

, 2009
In this paper, we demonstrate the existence and localization of fucosyl-containing O-glycoforms of nucleolin in cultured bovine endothelial cells (CVEC) and malignant cultured human A431 cells.
ROSATI, FLORIANA, ZICHE, MARINA, ALDI, SILVIA, DELLA GIOVAMPAOLA, CINZIA, FOCARELLI, RICCARDO, ARMINI, ALESSANDRO, FINETTI, FEDERICA   +6 more
core   +1 more source

Quiescent HSCs exhibit cytosolic sequestration of nucleolin.

, 2012
(A) Nucleolin colocalizes with the overexpressed G0S2 protein in LSK CD150+ CD48− cells purified from mice transplanted with BM cells transduced with the MIGR1-G0S2 V5-tagged retrovirus. (B) Expression of nucleolin and Ki67 was determined in wild-type LS−
Daisuke Nakada (160813), H. Daniel Lacorazza (160818), Chun Shik Park (160804), Audrea Burns (160808), Takeshi Yamada (160800)   +4 more
core   +1 more source

Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin.

PLoS ONE, 2014
Fragile X mental Retardation Protein (FMRP) is a well-known regulator of local translation of its mRNA targets in neurons. However, despite its ubiquitous expression, the role of FMRP remains ill-defined in other cell types. In this study we investigated
Mohamed S Taha, Kazem Nouri, Lech G Milroy, Jens M Moll, Christian Herrmann, Luc Brunsveld, Roland P Piekorz, Mohammad R Ahmadian   +7 more
doaj   +1 more source

Nucleolin Is Required for RNA Polymerase I Transcription In Vivo

, 2006
Eukaryotic genomes are packaged with histones and accessory proteins in the form of chromatin. RNA polymerases and their accessory proteins are sufficient for transcription of naked DNA, but not of chromatin, templates in vitro.
LeRoy, Gary, Flint, S., Rickards, Brendan, Cole, Michael D   +3 more
core   +1 more source

Myogenic Anti-Nucleolin Aptamer iSN04 Inhibits Proliferation and Promotes Differentiation of Vascular Smooth Muscle Cells

Biomolecules
De-differentiation and subsequent increased proliferation and inflammation of vascular smooth muscle cells (VSMCs) is one of the mechanisms of atherogenesis.
Mana Miyoshi, Takeshi Shimosato, Tomohide Takaya   +2 more
doaj   +1 more source

Interaction of Host Nucleolin with Influenza A Virus Nucleoprotein in the Early Phase of Infection Limits the Late Viral Gene Expression.

PLoS ONE, 2016
Influenza A virus nucleoprotein, is a multifunctional RNA-binding protein, encoded by segment-5 of the negative sense RNA genome. It serves as a key connector between the virus and the host during virus replication.
Deepshikha Kumar, Shobha Broor, Maitreyi S Rajala   +2 more
doaj   +1 more source

Nucleolin inhibits G4 oligonucleotide unwinding by Werner helicase.

PLoS ONE, 2012
BackgroundThe Werner protein (WRNp), a member of the RecQ helicase family, is strongly associated with the nucleolus, as is nucleolin (NCL), an important nucleolar constituent protein.
Fred E Indig, Ivana Rybanska, Parimal Karmakar, Chakravarty Devulapalli, Haiqing Fu, France Carrier, Vilhelm A Bohr   +6 more
doaj   +1 more source