Results 71 to 80 of about 12,341 (216)
This review systematically elucidates the multifactorial anti‐aging mechanisms of extracellular vesicles (EVs). By bridging fundamental biology with advanced bioengineering, scalable manufacturing, and clinical translation, it establishes a comprehensive framework for developing next‐generation EVs‐based precision nanotherapeutics to combat systemic ...
Xian Huang +6 more
wiley +1 more source
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng +3 more
wiley +1 more source
ABSTRACT mRNA‐based therapeutics offer significant potential for cancer treatment owing to their ability to induce transient, non‐integrating expression of therapeutic proteins. However, effective and tumour‐specific delivery remains a major barrier.
Dandan Wang +8 more
wiley +1 more source
A–B. Specific reduction of surface but not nuclear nucleolin in HB-19 treated cells. MDA-MB-231 cells were cultured with HB-19 at 0, 1, 2.5, 5 and 10 µM of for 5 hours before preparation of cytoplasmic (i.e, containing cytoplasmic and plasma membrane ...
Ara G. Hovanessian (49498) +5 more
core +1 more source
Abunmix enables the simple and robust multiplexed immunofluorescence imaging
Multiplexed fluorescence imaging is limited by bleed‐through signals arising from the use of antibodies derived from the same host species. Abunmix can separate signals from multiple antibodies generated from the same host species using a signal unmixing algorithm.
Woonggi La +14 more
wiley +1 more source
Identification of nucleolin as a
γ-H2AX-interacting protein. (A) phospho-mimic GST-H2AX (H2AXS139E) pulls down several proteins including nucleolin from the nuclear extract of irradiated HeLa cells. Proteins were visualized by silver staining.
Hiroko Fujimoto (122496) +7 more
core +1 more source
BackgroundEmerging evidences suggest that nucleolin expressed on the cell surface is implicated in growth of tumor cells and angiogenesis. Nucleolin is one of the major proteins of the nucleolus, but it is also expressed on the cell surface where is ...
Damien Destouches +9 more
doaj +1 more source
Nucleolin mediates the antiangiogenesis effect of the pseudopeptide N6L
Background Nucleolin is a protein over-expressed on the surface of activated cells. Recent studies have underlined the involvement of cell surface nucleolin in angiogenesis processes.
Birmpas Charalampos +3 more
doaj +1 more source
From modular COF design to biomedical translation, this Review maps how linkage chemistry, topology, pore environment, and particle engineering govern bioperformance, therapeutic and diagnostic function, safety, and clinical readiness. Covalent organic frameworks (COFs) are a versatile class of crystalline porous materials with growing potential in ...
Julia Kolodziejczyk +1 more
wiley +1 more source
Noise-induced hearing loss (NIHL) is the most significant occupational health issue worldwide. We conducted a genome-wide association study to identify single-nucleotide polymorphisms (SNPs) associated with hearing threshold shift in young males ...
Yohann Grondin +7 more
doaj +1 more source

