Results 81 to 90 of about 12,341 (216)

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

Advanced Science, Volume 13, Issue 27, 13 May 2026.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei, Wenzhu Peng, Zekun Huang, Bingye Yang, Yiyu Wu, Minzhen Han, Yi Wang, Bingling Peng, Guosheng Hu, Jiawei Hong, Guijia Liu, Linwei Nie, Yang Gan, Miaoqin Huang, Xuan Luo, Weiwei You, Wen Liu, Caihuan Ke   +17 more
wiley   +1 more source

PVT1 interacts with nucleolin in SiHa cells.

, 2016
(A) SiHa cells stained for PVT1 (green) and nucleolin (red), and DAPI. Boxed cells (top panel) are at higher magnification (bottom panel). White arrows show PVT1-nucleolin colocalization. Scale bars = 20μM.
Janet S. Rader (93781), Ramani Ramchandran (229021), Samantha Fye (616221), Keguo Li (465165), Tamjid Chowdhury (3166638), Marissa Iden (3166635)   +5 more
core   +1 more source

Affinity‐Based Interactome Mapping of Inositol Pyrophosphates Reveals 4/6‐PP‐InsP5‐Binding Proteins in Plants

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ABSTRACT Inositol pyrophosphates (PP‐InsPs) are central regulators of eukaryotic signaling events. While certain PP‐InsP isomers have been conclusively linked to the regulation of phosphate homeostasis through interaction with SPX domain‐containing proteins in plants, the functions of the recently discovered isomer 4/6‐PP‐InsP5 remain largely unknown ...
Kevin Ritter, Verena Gaugler, Sara Christina Stolze, Riya Ghosh, Akhila Jayamon, Ranjana Yadav, Felix Wollensack, Debabrata Laha, Hirofumi Nakagami, Gabriel Schaaf, Henning Jacob Jessen   +10 more
wiley   +1 more source

Nucleolin-aptamer therapy in retinoblastoma: molecular changes and mass spectrometry-based imaging

, 2016
Retinoblastoma (RB) is an intraocular childhood tumor which, if left untreated, leads to blindness and mortality. Nucleolin (NCL) protein which is differentially expressed on the tumor cell surface, binds ligands and regulates carcinogenesis and ...
N Subramanian (13475326), RK Kanwar (14450685), T Pradeep (13661575), JR Kanwar (14450679), V Khetan (13475338), A Srimany (13661566), P Rishi (13661572), B Akilandeswari (13661569), M Vasudevan (12530954), S Krishnakumar (13475344)   +9 more
core  

RGS6 drives cardiomyocyte death following nucleolar stress by suppressing Nucleolin/miRNA-21

Journal of Translational Medicine
Background Prior evidence demonstrated that Regulator of G protein Signaling 6 (RGS6) translocates to the nucleolus in response to cytotoxic stress though the functional significance of this phenomenon remains unknown.
Abhishek Singh Sengar, Manish Kumar, Chetna Rai, Sreemoyee Chakraborti, Dinesh Kumar, Pranesh Kumar, Sukhes Mukherjee, Kausik Mondal, Adele Stewart, Biswanath Maity   +9 more
doaj   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, Volume 46, Issue 3, Page 672-712, May 2026.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

Nucleolin binds to FGF1 and FGF2.

, 2014
A) Proteins from cleared cell lysates (BJ or NIH3T3 cells) were pulled down by SBP-FGF1, Biot-FGF2, His-FGF1, GST-FGF1, GST-FGF2, GST protein, or no protein (–), and respective resins (Streptavidin-coated Dynabeads, Ni-NTA Superflow or Glutathione ...
Torunn Sletten (530507), Mandana Yadollahi (530511), Joanna Bober (530509), Justyna Tomala (530512), Jacek Otlewski (530513), Malgorzata Zakrzewska (214224), Michal Kostas (530508), Vigdis Sorensen (530510), Antoni Wiedlocha (530514), Sjur Olsnes (214230)   +9 more
core   +1 more source

Evaluation of somatostatin and nucleolin receptors for therapeutic delivery in non-small cell lung cancer stem cells applying the somatostatin-analog DOTATATE and the nucleolin-targeting aptamer AS1411.

PLoS ONE, 2017
Cancer stem cells represent the putative tumor-driving subpopulation thought to account for drug resistance, relapse, and metastatic spread of epithelial and other cancer types.
Sif Holmboe, Pernille Lund Hansen, Helge Thisgaard, Ines Block, Carolin Müller, Niels Langkjær, Poul Flemming Høilund-Carlsen, Birgitte Brinkmann Olsen, Jan Mollenhauer   +8 more
doaj   +1 more source

Nucleolin binds to the four ErbB receptors.

, 2013
(A) COS7 cells were transiently co-transfected with expression vector of each of the ErbB receptors and Myc-Nucleolin. Cell lysates were separated into cytosolic (supernatant) and total membrane (pellet) fractions.
Keren Farin (86092), Ronit Pinkas-Kramarski (86093), Ayelet Di Segni (86091)   +2 more
core   +1 more source

The crosstalk between ErbB1 and nucleolin

Communicative & Integrative Biology, 2009
The ErbB receptor tyrosine kinases are major contributors to malignant transformation. These receptors are frequently overexpressed in a variety of human carcinomas. Ligand binding to specific ErbB receptor is followed by receptor dimerization, phosphorylation and recruitment of SH2 containing cytoplasmic proteins, which initiate the cascade of ...
Keren Farin, Ronit Pinkas-Kramarski
openaire   +1 more source