Results 61 to 70 of about 12,341 (216)
Nucleolin accumulates at DSB damage sites.
, 2012 (A) GFP-nucleolin is confined into nucleolus without DNA damage and diffuses to nucleolpasm after DNA-damaging treatment (CPT 1 µM; etoposide 1 µM) in HeLa cells.
Hiroko Fujimoto (122496) +7 more
core +1 more source
Identification of a role for nucleolin in rabies virus infection [PDF]
, 2015 Full text Embargoed until: 2015-08-31Rabies virus replicates in the cytoplasm of host cells, but rabies virus phosphoprotein (P-protein) undergoes active nucleocytoplasmic trafficking.
Oksayan, S +5 more
core +1 more source
Nucleolin regulates phosphorylation and nuclear export of fibroblast growth factor 1 (FGF1).
PLoS ONE, 2014 Extracellular fibroblast growth factor 1 (FGF1) acts through cell surface tyrosine kinase receptors, but FGF1 can also act directly in the cell nucleus, as a result of nuclear import of endogenously produced, non-secreted FGF1 or by transport of ...
Torunn Sletten +9 more
doaj +1 more source
PROTEOMICS, EarlyView.ABSTRACT Triple‐negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high metastatic potential, poor prognosis, and limited effective therapeutic options. In this study, we investigated the molecular mechanisms underlying the anticancer effects of the nucleolin (NCL)‐targeting DNA aptamer AS1411 using label‐free ...
Ha‐Song Bae +6 more
wiley +1 more source
In SituLocalization of Nucleolin in the Plant Nucleolar Matrix
Experimental Cell Research, 1996 The analysis of isolated nucleolar matrices from onion cells by light and electron microscopy, 2-D separation of proteins, and confocal microscopy has confirmed the existence of an organized nucleolar matrix with a complex protein composition to which are attached the insoluble processing complexes.
Mínguez Garrido, Ana +1 more
openaire +3 more sources
The 212 C-terminal aa of nucleolin are important for nucleolin ErbB interaction.
, 2013 GST pull-down assay showing ErbB4 interaction with nucleolin and nucleolin mutants. (A) Schematic presentation of nucleolin deletion mutants. (B) HEK-293T cells were transfected with pEGFP (empty vector), pEGFP-nucleolin-myc or pEGFP-nucleolin-myc mutant
Keren Farin (86092) +3 more
core +1 more source
DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity
Small, EarlyView.DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley +1 more source
Nucleolin Interacts with Telomerase
, 2019 Telomerase is a specialized reverse transcriptase composed of core RNA and protein subunits which plays essential roles in maintaining telomeres in actively dividing cells.
Khurts, Shilagardi +8 more
core +1 more source
Molecular Interplay of PARN and Telomerase: Tail Modifiers and Disease Implications
WIREs RNA, Volume 17, Issue 4, July/August 2026.Schematic representation of the molecular interplay between PARN, telomerase‐associated, and the involvement of p53 in regulating telomere maintenance and genome stability. The top panel shows how normal PARN levels are involved in regulating p53 levels and balanced telomerase activity through their regulatory interaction with TERC and TERRA, thus ...
Sujitha Felicitus +5 more
wiley +1 more source
Nucleolin induces ErbB1 dimerization.
, 2013 COS7 cells were transiently co-transfected with expression vector of ErbB1 receptors alone or with Myc-Nucleolin. Following 30 min serum deprivation cells were untreated or treated with EGF 100 ng/ml for 5 min.
Keren Farin (86092) +2 more
core +1 more source