Results 191 to 200 of about 12,341 (216)

The Multiple Properties and Functions of Nucleolin

2011
Nucleolin, one of the most abundant proteins of the nucleolus is a fascinating protein with multiple proposed functions within and outside the nucleoli. Since its discovery almost 40 years ago, it was proposed that nucleolin is involved in ribosome biogenesis but until recently the molecular mechanisms of this involvement were not known.
Rong Cong, Sadhan Das, Philippe Bouvet
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Nucleolin Responds to DNA Damage

Science Signaling, 2002
Stimuli that damage DNA activate stress-signaling pathways that include the activation of the tumor suppressor p53. Daniely et al. report that ionizing radiation (IR) or the drug camptothecin produce a transient p53-dependent redistribution of nucleolin from nucleoli to the nucleoplasm.
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[Protein phosphatases and nucleolin in osteoblastic cells: cleavage of nucleolin in apoptotic cells].

Kaibogaku zasshi. Journal of anatomy, 2003
Protein phosphorylation and dephosphorylation has been recognized as a key mechanism in cell proliferation, differentiation, and apoptosis in various tissues. Okadaic acid is a potent inhibitor of protein phosphatase type 1 (PP1) and type 2A and induces apoptosis in human osteoblastic Saos-2 and MG63 cells.
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Molecular mechanism of nucleolin-mediated Pol I transcription and characterization of nucleolin acetylation

Rôle de la nucléoline dans le mécanisme moléculaire de la regulation de la transcription par la polymérase I et caractérisation de son acétylation Nous montrons dans cette étude que dans les cellules déplétées pour la nucléoline, une plus faible accumulation de pré-ARNr est associée à une augmentation de marques d’hétérochromatine ...
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Regulation of MDM2 Activity by Nucleolin

2005
Abstract : The major accomplishment of our studies is the finding that nucleolin stabilizes p53 by inhibiting the p53-antagonist Hdm2. The increase in p53 protein by nucleolin leads to higher expression of p21cip1/waf1 a reduced rate of cellular proliferation and an increase in apoptosis.
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nucleolin, n.²

2023
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Identifizierung der Interaktionsproteine von Nucleolin und Charakterisierung einer neuen Funktion von Nucleolin durch die Überexpression von Nucleolin-GFP-Fusionsproteinen

2001
[no abstract]
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Nucleolin

2008
openaire   +2 more sources

A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity

Cell, 2018
Michelle Percharde, Chih-Jen Lin, Yafei Yin   +2 more
exaly  

The Cell-Surface-Expressed Nucleolin Is Associated with the Actin Cytoskeleton

Experimental Cell Research, 2000
Ara G Hovanessian, Sébastien Nisole, Emmanuelle Perret   +2 more
exaly