Results 71 to 80 of about 91,885 (305)
Effect of Urtica dioica L extract on quantitative morphometric alterations of liver parenchymal cells in STZ diabetic rats [PDF]
, 2009 Diabetes is associated with several structural and functional liver abnormalities that affect glycogen and lipid metabolism. In this study, an attempt was made to evaluate the effects of hydroalcoholic extract of Urtica dioica leaves on Quantitative ...
Farsi, M.M. +2 more
core +1 more source
The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation
Advanced Science, EarlyView.ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley +1 more source
Nucleolar origins: challenging perspectives on evolution and function
Open BiologyThe nucleolus, once considered a mere ‘ribosome factory’, is now recognized as a dynamic hub influencing nearly every aspect of cellular life, from genome organization to stress response and ageing.
Israel Muñoz-Velasco +2 more
doaj +1 more source
Matching games: the least core and the nucleolus [PDF]
, 2000 A matching game is a cooperative game defined by a graph $G=(V,E)$. The player set is $V$ and the value of a coalition $S \subseteq V$ is defined as the size of a maximum matching in the subgraph induced by $S$.
Kern, W., Paulusma, D.
core +1 more source
Advanced Science, EarlyView.Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang +10 more
wiley +1 more source
Consistency, converse consistency, and aspirations in TU-games [PDF]
, 2003 In problems of choosing ‘aspirations’ for TU-games, we study two axioms, ‘MW-consistency’ and ‘converse MW-consistency.’ In particular, we study which subsolutions of the aspiration correspondence satisfy MW-consistency and/or converse MW-consistency. We
Hokari, Toru +2 more
core +1 more source
Advanced Science, EarlyView.Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian +5 more
wiley +1 more source
Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development
Advanced Science, EarlyView.Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu +8 more
wiley +1 more source
A Nucleolus for Stochastic Cooperative Games [PDF]
This paper extends the definition of the nucleolus to stochastic cooperative games, that is, to cooperative games with random payoffs to the coalitions.
Suijs, J.P.M.
core +1 more source
Nucleolar Localization of HIV-1 Rev Is Required, Yet Insufficient for Production of Infectious Viral Particles. [PDF]
, 2018 Combination antiretroviral therapy fails in complete suppression of HIV-1 due to drug resistance and persistent latency. Novel therapeutic intervention requires knowledge of intracellular pathways responsible for viral replication, specifically those ...
Arizala, Jerlisa Ann C +5 more
core +1 more source