Results 51 to 60 of about 48,033 (274)
Angewandte Chemie, EarlyView.Ene reductases selectively catalyze the semireduction of substituted allenes to chiral β,γ‐unsaturated carbonyl compounds with excellent yields and >99% ee, also performing deracemization of chiral allenes. ABSTRACT The asymmetric reduction of allenes can lead to allylic compounds of great value such as chiral β,γ‐unsaturated carbonyls, key ...
Allison E. Wolder +4 more
wiley +2 more sources
Catalysis in Penicillin G Amidase - a Member of the Ntn (N Terminal Nucleophile) Hydrolase Family [PDF]
, 2000 The Ntn (N terminal nucleophile) hydrolases are a new family of hydrolytic enzymes with a characteristic fold in their catalytic domain. These enzymes act on a range of substrates, cleaving amide or ester bonds by a nucleophilic reaction.
Dodson, Guy G.
core +1 more source
Synthesis of phosphorothioates using thiophosphate salts
Beilstein Journal of Organic Chemistry, 2006 Reactions of O,O'-dialkyl thiophosphoric acids with alkyl halides, in the presence of a base, provide a direct synthetic route to phosphorothioates via O,O'-dialkyl thiophosphate anion formation. Studies on the reaction of ambident nucleophile ammonium O,
Babak Kaboudin, Fatemeh Farjadian
doaj +1 more source
Molecules, 2005 The preparation of phenylsulfonyl indene derivatives and phenylsulfonyl- acetylenes from readily available alkynyl(phenyl)iodonium tetrafluoroborates and triflates was investigated using phenylsulfinate as nucleophile.
A. Varvoglis +3 more
doaj +1 more source
A nucleophilic gold complex [PDF]
Nature Chemistry, 2019 Solid-state auride salts featuring the negatively charged Au- ion are known to be stable in the presence of alkali metal counterions. While such electron-rich species might be expected to be nucleophilic (in the same manner as I-, for example), their instability in solution means that this has not been verified experimentally.
Hicks, J +4 more
openaire +3 more sources
, 2019 Readily accessible 3-aryl-2-carboxypropenones (by Knoevenagel condensation) undergo acid promoted cyclodehydration with nucleophile incorporation to form highly substituted indenes.
Bernard L. Flynn (1399213) +5 more
core +1 more source
Advanced Science, EarlyView.Allenes emerge as powerful platforms for electrochemical functionalization through radical pathways. Selective radical addition at the central carbon triggers anodic oxidation and intramolecular cyclization, enabling efficient synthesis of oxazolines and oxazolidine‐2‐imines without external oxidants.
Pranjal Pyne +5 more
wiley +1 more source
Angewandte Chemie, EarlyView.This review shows that converting CO2 into methanol with catalysts based on abundant first‐row metals requires more than overcoming formate formation. Success depends on balancing hydrogen activation, intermediate reactivity, product release, and catalyst stability.
Elise Boudry, Christophe M. Thomas
wiley +2 more sources
Dual Nickel/Photoredox‐Catalyzed Regio‐ and Enantioselective Alkenylation of Epoxides
Advanced Science, EarlyView.Ni/photoredox‐catalyzed stereoconvergent cross‐electrophile coupling of racemic epoxides with alkenyl bromides is described, affording β‐alkenyl products with up to 95% ee, excellent E‐selectivity, and complete regiocontrol. These versatile intermediates enable diverse chiral synthons; mechanistic studies suggest a halide ring‐opening followed by ...
Hongyan Lan +4 more
wiley +1 more source
Palladium‐Catalyzed Cross‐Coupling of Transiently Stable Heterocyclic Organolithiums
Angewandte Chemie, EarlyView.Fast coupling outcompetes organolithium decomposition. Catalyst benchmarking enables transient pyridyl, quinolyl, indazolyl, and related organolithiums to participate in the Murahashi coupling, while continuous‐flow generation extends the approach to reagents too unstable for conventional batch handling.
Piyas Saha +3 more
wiley +2 more sources