Results 161 to 170 of about 14,867 (213)

Homeostatic regulation of nucleoporins is a central driver of nuclear pore biogenesis. [PDF]

Cell Rep
Sakuma S, Raices M, Zhu EYS, Mamriev D, Fisher CI, Heynen-Genel S, D'Angelo MA.   +6 more
europepmc   +1 more source

Nucleoporins in Cancer: Functional Roles and Therapeutic Opportunities. [PDF]

Cancer Discov
Kirthika P, Jawalagatti V, Carceles-Cordon M, Domingo-Domenech J, Rodriguez-Bravo V.   +4 more
europepmc   +1 more source

Elaboration of molecular glues that target TRIM21 into TRIMTACs that degrade protein aggregates. [PDF]

Nat Commun
Scemama de Gialluly MA, Allen AR, Hayes EH, Zhuang P, Goldfarb RB, Farrar AN, Fedorov Y, Adams DJ.   +7 more
europepmc   +1 more source

Enterovirus D68 2A protease causes nuclear pore complex dysfunction and independently contributes to motor neuron toxicity. [PDF]

Elife
Zinn KM, McLaren MW, Imai MT, Jayaram MM, Rothstein JD, Elrick MJ.   +5 more
europepmc   +1 more source

Hydration free energy is an incomplete predictor of globular protein incorporation into condensates. [PDF]

Biophys J
Anderson S, Harrison M, Dignon GL.
europepmc   +1 more source

C9orf72 ALS-causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules. [PDF]

FEBS Lett
Bilican S, Nabawi Y, Zhang WH, Petrovic D, Wehrmann M, Muñoz-García S, Koyuncu S, Vilchez D.   +7 more
europepmc   +1 more source

ELYS promotes hepatocellular carcinoma stemness by activating a FOXO6-NUP205 transcriptional module downstream of PI3K/AKT to drive Hedgehog signaling. [PDF]

Cell Biosci
Chen X, Zhang Q, Xie F, Zhai H, Li C, Zhou W, Zhang N.   +6 more
europepmc   +1 more source

Nuclear basket proteins Nup2 and Mlp1 drive heat shock-induced 3D genome restructuring downstream of transcriptional activation. [PDF]

J Biol Chem
Mohajan S, Rubio LS, Gross DS.
europepmc   +1 more source

Lamin A/C loss promotes R-loop-mediated genomic instability and poor survival in small-cell lung cancer. [PDF]

Proc Natl Acad Sci U S A
Schultz CW, Saha S, Dhall A, Zhang Y, Desai P, Pongor LS, Scheiblin DA, Magidson V, Shuklah RP, Sebastian R, Vekariya UM, Ahmed S, Sun Y, Redon C, Kumar S, Krishnamurthy M, Dias HB, Aksenova V, Giordano E, Takahashi N, Nirula M, Arora M, Tabe C, Thomas MS, Kumar R, Arakawa Y, Jo U, Skorski T, Teicher BA, Shreshta R, Aladjem MI, Lockett S, Dasso M, Pommier Y, Sharma AK, Thomas A.   +35 more
europepmc   +1 more source

Dystonia: Insights into Mechanisms and Novel Therapeutics. [PDF]

Curr Neurol Neurosci Rep
Dzinovic I, Zech M.
europepmc   +1 more source