Results 111 to 120 of about 7,557 (223)
The Role of CD4 T Cell Repertoire and Immune Memory Mechanisms in Vaccination and Infection Immunity
ABSTRACT CD4+ T cells orchestrate adaptive immunity against respiratory viruses through functionally distinct subsets, yet the qualitative differences between vaccine‐ and infection‐induced responses remain incompletely understood. This review summarizes current evidence on how CD4+ T cell subsets shape the magnitude, breadth, and durability of ...
Masato Kubo
wiley +1 more source
Modern cancer therapy: cryoablation meets immune checkpoint blockade
Cryoablation, as a minimally invasive technology for the treatment of tumors, destroys target tumors with lethal low temperatures. It simultaneously releases a large number of tumor-specific antigens, pro-inflammatory cytokines, and nucleoproteins, known
Qi Liu +8 more
doaj +1 more source
ABSTRACT Introduction Crimean‐Congo haemorrhagic fever virus (CCHFV) is a tick‐borne zoonotic pathogen of major public health importance in Africa. Although CCHFV exposure has been reported in several livestock species in Nigeria, data on equids remain limited despite their extensive involvement in livestock movement and trade.
David O. Ehizibolo +14 more
wiley +1 more source
Segmented negative strand RNA virus nucleoprotein structure [PDF]
International audienceNegative strand RNA virus (NSV) genomes are never free, but always found assembled with multiple copies of their nucleoprotein, as RNPs.
Cusack, Stephen +2 more
core +1 more source
Negative and ambisense RNA virus ribonucleocapsids: more than protective armor. [PDF]
Sabsay KR, Te Velthuis AJW.
europepmc +1 more source
Abstract Despite advancements in reperfusion therapy, myocardial ischaemia–reperfusion (IR) injury remains a major clinical challenge. This study investigated whether a novel dual‐target pre‐conditioning strategy using sinomenine and irisin could enhance myocardial resistance against IR injury. Ninety male Sprague–Dawley rats were utilized.
Lianjun Wu +3 more
wiley +1 more source
G-quadruplex-forming small RNA inhibits coronavirus and influenza A virus replication
Future pandemic threats may be caused by novel coronaviruses and influenza A viruses. Here we show that when directly added to a cell culture, 12mer guanine RNA (G12) and its phosphorothioate-linked derivatives (G12(S)), rapidly entered cytoplasm and ...
Ryoya Sekine +16 more
doaj +1 more source
Since the specific capacity and tolerance of cells, including sperm proteins depend on their natural, it was necessary to study the protein fractions changes depending on the semen storage temperature.
USM ADMIN
doaj
Exposure history-independent protection by universal influenza vaccine targeting nucleoproteins of A and B type [PDF]
Current influenza vaccines are neutralizing antibody-based vaccines targeting hemagglutinin and neuraminidase which are highly variable surface glycoproteins.
박경주
core

