Results 131 to 140 of about 25,304 (272)

Structural and Functional Diversity of Nairovirus-Encoded Nucleoproteins

Journal of Virology, 2015
Wenming Wang, Xiang Liu, Xu Wang, Hui Dong, Chao Ma, Jing-Ming Wang, Baocheng Liu, Yong-Hong Mao, Ying Wang, Ting Li, Cheng Yang, Yu Guo   +11 more
semanticscholar   +1 more source

Survey of Rift Valley Fever Virus Antibodies and Risk Factors in Small Ruminants in Maiduguri, Borno State, Nigeria: A Cross‐Sectional Serological Study

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
High seroprevalence of Rift Valley fever virus antibodies (47.9%) in small ruminants in Maiduguri indicates substantial past exposure. Age, sex, and residence in flood‐prone areas were significant risk factors, highlighting the need for targeted surveillance and vector control to reduce livestock and public health impacts.
Sani Mohammed, Abdulrahman Mohammed, Adamu Saleh Saidu, Muhammad Mamman Gashua, Shuaibu Gidado Adamu, Ibrahim Malami Yusuf, Daniel Jigbin, Abdulyekeen O. Tijani, Hassan Ismail Musa   +8 more
wiley   +1 more source

Conditional eIF2A Deletion Suggests Extra‐Adipose Mechanisms Underlying Metabolic Syndrome in Total‐Body eIF2A Knockout Mice

FASEB BioAdvances, Volume 8, Issue 9, September 2026.
Adipose tissue‐specific deficiency of eIF2A is insufficient to reproduce the metabolic defects observed in total‐body eIF2A knockout mice, suggesting that the systemic metabolic effects observed in these mice may arise from coordinated functions across multiple organs.
Adedeji Isaac Adeloye, Richard Anderson, Anchal Agarwal, Barsanjit Mazumder, Taras Y. Nazarko, Atefeh Bagheri, Archana Prabahar, Peng Jiang, Frank Tedeschi, William C. Merrick, David A. Buchner, Maria Hatzoglou, Roman V. Kondratov, Anton A. Komar   +13 more
wiley   +1 more source

Prenatal Alcohol Exposure Produces Selective Changes in Neuroimmune Gene Expression Across Brain Regions of Adult Mice

Alcohol, Clinical and Experimental Research, Volume 50, Issue 9, September 2026.
PAE creates a unique inflammatory signature in the mature adult brain with region‐specific changes in genes implicated in glial‐immune function. We report at least 60 differentially expressed genes in different brain regions due to PAE, many of which are associated with neuroimmune function.
Alissa N. Jones, Ariana N. Pritha, Ashlynn M. Aguilar, Andrea A. Pasmay, Justin R. Carter, Nikolaos Mellios, Shahani Noor   +6 more
wiley   +1 more source

Proteostasis of organelles in aging and disease

The FEBS Journal, Volume 293, Issue 18, Page 5600-5626, September 2026.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

The FEBS Journal, Volume 293, Issue 17, Page 5340-5362, September 2026.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior, Maria Anastasia Doumani, Hao Fu, Jelle van den Bor, Olof Idevall‐Hagren, Aristidis Moustakas   +5 more
wiley   +1 more source

Disruption of iron metabolism resulting from Dmt1/Slc11a2 deficiency compromises Notch protein degradation and transcriptional activation

The FEBS Journal, Volume 293, Issue 17, Page 5383-5395, September 2026.
Divalent metal transporter 1 (Dmt1) maintains iron homeostasis and lysosomal proteostasis required for physiological Notch receptor–ligand signaling. Dmt1 loss lowers iron storage capacity (ferritin), increasing intracellular Fe2+, driving ROS and lipid peroxidation, and leading to lysosomal/mitochondrial dysfunction.
Rui Zhang, Somaieh Ahmadian, Jolanda Piepers, Florian Bock, Tom Keulers, Marc A. Vooijs   +5 more
wiley   +1 more source

BLIMP‐1 and CD39 expression define human effector memory regulatory T cells in blood and recall responses to viruses

Immunology &Cell Biology, Volume 104, Issue 8, Page 757-767, September 2026.
This study found that BLIMP‐1 is highly expressed in activated effector/memory human regulatory T cells, especially CD39+ Tregs, where it is associated with increased IL‐10 production and a conserved phenotype across blood and lung tissues during immune responses such as SARS‐CoV‐2 infection.
Chansavath Phetsouphanh, Laura Cook, Katherine J. L. Jackson, Deirdre Cuff, Vera Klemm, Bikash Manandhar, Denise C. Hsu, Yin Xu, John J. Zaunders, Anthony D. Kelleher, Nabila Seddiki   +10 more
wiley   +1 more source

Arenavirus Nucleoproteins Prevent Activation of Nuclear Factor Kappa B

Journal of Virology, 2012
W. W. I. S. Rodrigo, Emilio Ortiz-Riaño, Christelle Pythoud, S. Kunz, J. C. de la Torre, L. Martínez-Sobrido   +5 more
semanticscholar   +1 more source

H5N1 Clade 2.3.4.4b Infections in Domestic Cats During an Avian Influenza Outbreak in Italy: Implications for One Health Surveillance

Influenza and Other Respiratory Viruses, Volume 20, Issue 9, September 2026.
ABSTRACT Background H5Nx goose/Guangdong (Gs/GD) lineage highly pathogenic avian influenza (HPAI) viruses pose a significant public health threat due to their global spread, mutation accumulation, and expanding host range. The descendant clade 2.3.4.4b has been causing widespread infections in birds and increasing spillover events in mammals.
Giulia D'Annunzio, Ana Moreno, Giovanni Tosi, Patrizia Bassi, Alessio Bortolami, Giuseppe Diegoli, Alessandra Drago, Alice Fusaro, Luca Gelmini, Lucia Rita Gibelli, Tiziana Lazzarotto, Elisabetta Lilliu, Luisa Loli Piccolomini, Andrea Maroni, Enrica Martini, Giulio Matteo, Giovanna Mattei, Luisa Vera Muscatello, Isabella Monne, Elisa Palumbo, Giorgia Prezzemolo, Valentina Ravaioli, Davide Resi, Luigi Ruocco, Michele Ottavio Sabatino, Enrico Savegnago, Marco Sordilli, Calogero Terregino, Clara Tolini, Giuseppe Merialdi   +29 more
wiley   +1 more source