Results 31 to 40 of about 15,615 (292)

Antimitotic action of cornin as a biologically active polypeptide. II. Physiological effects of cornin on dividing cell [PDF]

open access: yes, 1965
Both the cornea and muscle cornins have no effect at all on oxygen uptake of tissue, and likewise they catalase affect Qctivity not in any way. The corneacornin has an effect to reduce P/O ratio to about one half, but the muscle cornin does not show such
Murakami, Tetuhide H., Nisida, Isamu
core   +1 more source

Systemic Lupus Erythematosus and DNA Degradation and Elimination Defects

open access: yesFrontiers in Immunology, 2019
Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is characterized by the production of autoantibodies specific for components of the cell nucleus and that causes damage to body tissues and organs.
Borros Arneth
doaj   +1 more source

Complete sequence of the genome of the human isolate of Andes virus CHI-7913: comparative sequence and protein structure analysis [PDF]

open access: yes, 2003
Indexación: ScieloWe report here the complete genomic sequence of the Chilean human isolate of Andes virus CHI-7913. The S, M, and L genome segment sequences of this isolate are 1,802, 3,641 and 6,466 bases in length, with an overall GC content of 38.7%.
Fernández, Jorge   +9 more
core   +2 more sources

Intracellular Crosslinking of Filoviral Nucleoproteins with Xintrabodies Restricts Viral Packaging

open access: yesFrontiers in Immunology, 2017
Viruses assemble large macromolecular repeat structures that become part of the infectious particles or virions. Ribonucleocapsids (RNCs) of negative strand RNA viruses are a prime example where repetition of nucleoprotein (NP) along the genome creates a
Tamarand Lee Darling   +3 more
doaj   +1 more source

Controllable self-replicating RNA vaccine delivered intradermally elicits predominantly cellular immunity

open access: yesiScience, 2023
Summary: Intradermal delivery of self-replicating RNA (srRNA) is a promising vaccine platform. We have developed an srRNA that functions optimally at around 33°C (skin temperature) and is inactivated at or above 37°C (core body temperature) as a safety ...
Tomokazu Amano   +12 more
doaj   +1 more source

Native morphology of influenza virions

open access: yesFrontiers in Microbiology, 2012
Influenza A virus is an enveloped virus with a segmented, single-strand, negative-sense RNA genome. Its virions show spherical or filamentous shapes of about 100 nm in diameter and occasionally irregular morphology, which exemplifies the pleomorphic ...
Takeshi eNoda
doaj   +1 more source

A universal SARS‐CoV DNA vaccine inducing highly cross‐reactive neutralizing antibodies and T cells

open access: yesEMBO Molecular Medicine, 2022
New variants in the SARS‐CoV‐2 pandemic are more contagious (Alpha/Delta), evade neutralizing antibodies (Beta), or both (Omicron). This poses a challenge in vaccine development according to WHO.
Sofia Appelberg   +19 more
doaj   +1 more source

The increase in phosphorylation levels of serine residues of protein HSP70 during holding at 17ºC is concomitant with a higher cryotolerance of boar spermatozoa [PDF]

open access: yes, 2014
Boar-sperm cryopreservation is not usually performed immediately after semen collection, but rather a holding time (HT) of 4 h-30 h at 17 u C is spent before starting this procedure.
Bonet, Sergi   +5 more
core   +10 more sources

Binding of RNA by the Nucleoproteins of Influenza Viruses A and B

open access: yesViruses, 2016
This paper describes a biochemical study for making complexes between the nucleoprotein of influenza viruses A and B (A/NP and B/NP) and small RNAs (polyUC RNAs from 5 to 24 nucleotides (nt)), starting from monomeric proteins.
Alice Labaronne   +5 more
doaj   +1 more source

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