Results 91 to 100 of about 171,665 (294)

The cumulative analgesic effect of repeated electroacupuncture is modulated by Adora3 in the SCDH of mice with neuropathic pain

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Neuropathic pain management via repeated electroacupuncture. Abstract Background Existing remedial approaches for relieving neuropathic pain (NPP) are challenging and open the way for alternative therapeutic measures such as electroacupuncture (EA). The mechanism underlying the antinociceptive effects of repeated EA sessions, particularly concerning ...
Faisal Ayub Kiani   +6 more
wiley   +1 more source

Respiratory virus mRNA vaccines: mRNA Design, clinical studies, and future challenges

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Abstract Respiratory infectious diseases frequently erupt on a global scale, with RNA viruses, such as SARS‐CoV‐2, RSV, and influenza viruses, posing challenges to vaccine development due to their high mutation rates. Traditional vaccine development cycles are lengthy and struggle to keep pace with rapidly evolving viruses, whereas messenger RNA (mRNA)
Linlin Zheng, Han Feng
wiley   +1 more source

A Straightforward Diphenylmethyl Protection Method and Deprotection of Some Pyrimidine Nucleosides

open access: yesMolecules, 2013
Benzhydryl protection of primary and secondary alcohols has been reported previously via reaction with metal alcoholates. Our aim was to find generally useful and very mild conditions for the alcoholic protection and deprotection of nucleosides with the ...
Arthur van Aerschot, Milind Saudi
doaj   +1 more source

An Electrochemical Sensor for Tenofovir Monitoring

open access: yesAdvanced NanoBiomed Research, EarlyView.
A novel laser‐scribed graphene/ gold spiky nanostructures/molecularly imprinted polymer electrochemical sensor is developed for sensitive and selective detection of tenofovir (TFV) to support human immunodeficiency virus adherence monitoring. It showed a broad linear range (10 nM–200 μM), low detection limit (3 nM), and high recovery (92.5%–113%) in ...
Abdellatif Ait Lahcen, Gymama Slaughter
wiley   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

open access: yesHepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog   +12 more
wiley   +1 more source

Phosphorylmuramic Acid in Lactobacillus casei. Its Presence in Protein and in a Nucleoside-pyrophosphate Fraction. [PDF]

open access: bronze, 1959
Carl‐Henric de Verdier   +5 more
openalex   +1 more source

Metabolism‐Regulating Nanomedicines for Cancer Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley   +1 more source

Ion-Exchange Chromatography of Nucleoside Polyphosphates. [PDF]

open access: bronze, 1954
Rolf Bergkvist   +3 more
openalex   +1 more source

The Effects of Nucleosides On the Resistance of Normal Human Erythrocytes to Osmotic lysis12 [PDF]

open access: bronze, 1957
Ernst R. Jaffé   +4 more
openalex   +1 more source

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