Results 151 to 160 of about 339,632 (390)

An Electrochemical Sensor for Tenofovir Monitoring

Advanced NanoBiomed Research, EarlyView.
A novel laser‐scribed graphene/ gold spiky nanostructures/molecularly imprinted polymer electrochemical sensor is developed for sensitive and selective detection of tenofovir (TFV) to support human immunodeficiency virus adherence monitoring. It showed a broad linear range (10 nM–200 μM), low detection limit (3 nM), and high recovery (92.5%–113%) in ...
Abdellatif Ait Lahcen, Gymama Slaughter
wiley   +1 more source

Ion-Exchange Chromatography of Nucleoside Polyphosphates. [PDF]

, 1954
Rolf Bergkvist, Adam Deutsch, Chr. Klixbüll Jørgensen, Nils Andreas Sörensen   +3 more
openalex   +1 more source

Synthesis of novel 2-(2-(6-chloro-9H-purin-9-yl)ethoxy)-6-isobutoxy-tetrahydro-2H-pyran-3-ol as a potential antiviral agent

Molbank, 2006
In this paper we propose the synthesis of 2-(2-(6-chloro-9H-purin-9-yl)ethoxy)-6-isobutoxy-tetrahydro-2H-pyran-3-ol as a new potential antiviral agent Its structure has been confirmed by IR, 1H-NMR, 13C-NMR, UV and Mass spectroscopic data.
A. A. Jarrahpour, E. Torabi
doaj   +1 more source

Unexpected Accumulation of ncm\u3csup\u3e5\u3c/sup\u3eU and ncm\u3csup\u3e5\u3c/sup\u3es\u3csup\u3e2\u3c/sup\u3eU in a \u3cem\u3etrm9\u3c/em\u3e Mutant Suggests an Additional Step in the Synthesis of mcm\u3csup\u3e5\u3c/sup\u3eU and mcm\u3csup\u3e5\u3c/sup\u3es\u3csup\u3e2\u3c/sup\u3eU [PDF]

, 2011
Background Transfer RNAs are synthesized as a primary transcript that is processed to produce a mature tRNA. As part of the maturation process, a subset of the nucleosides are modified.
Anderson, James T., Byström, Anders S., Chen, Changchun, Huang, Bo   +3 more
core   +1 more source

Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA

Nucleic Acids Research, 2011
In vitro-transcribed mRNA has great therapeutic potential to transiently express the encoded protein without the adverse effects of viral and DNA-based constructs.
K. Karikó, Hiromi Muramatsu, J. Ludwig, D. Weissman   +3 more
semanticscholar   +1 more source

RESEARCHES ON PYRIMIDINES. LXXXIV. THE TRANSFORMATION BY HYDROLYSIS OF SECONDARY PYRIMIDINE NUCLEOSIDES INTO IMIDAZOL COMBINATIONS. [PDF]

, 1917
Treat B. Johnson, Sidney E. Hadley
openalex   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

Angewandte Chemie International Edition, EarlyView.
This review highlights mechanochemical strategies for the late‐stage modification of active pharmaceutical ingredients (APIs), providing a valuable resource for selecting substrates to evaluate the pharmaceutical potential of novel and existing (mechano)chemical protocols.
Johanna Templ, Lars Borchardt
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Isolation and Separation of the Pyrimidine Nucleosides of Yeast Ribosenucleic Acid [PDF]

, 1948
R. J. C. Harris, J. F. Thomas
openalex   +1 more source

The Cyp2b6 Gene Polymorphism and Phenotypic Correlation of Efavirenz-Based Combination Therapy Among the Niger Delta Ethnic Population: Implications in Modern Pharmacogenomics

Pharmacogenomics and Personalized Medicine, 2022
Samuel J Bunu, Azibanasamesa DC Owaba, Edebi N Vaikosen, Benjamin U Ebeshi Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Bayelsa State, NigeriaCorrespondence: Samuel J Bunu Tel ...
Bunu JS, Azibanasamesa DC Owaba, Vaikosen EN, Ebeshi BU   +3 more
doaj