Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review
Phytotherapy Research, EarlyView.ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley +1 more source
Anti-Toxoplasma activity of NBMPR is mediated through the inhibition of nucleoside and nucleobase transporters. [PDF]
Parasitol ResPan M +7 more
europepmc +1 more source
Rapid Communications in Mass Spectrometry, EarlyView.ABSTRACT Rationale Electrospray (ESI), the most popular desorption/ionization technique used in mass spectrometry‐based metabolomics, generates both protonated and deprotonated molecules, as well as adduct ions, sodium being the most frequent monoatomic cation entering their composition.
Annelaure Damont +9 more
wiley +1 more source
Research Review on Inhibitors of Lumpy Skin Disease Virus: From Biological Characteristics, Drug Repurposing, to Computer-Aided Drug Design. [PDF]
Int J MicrobiolZhao L +6 more
europepmc +1 more source
Photodegradable Hydrogels for On‐Demand Modeling of Age‐Related Spatiotemporal ECM Deformation
Small, EarlyView.A light‐tunable PEG hydrogel enables on‐demand, spatiotemporal modeling of drusen‐like ECM bulges in the aging outer retina. By precisely controlling bulge size, the platform reveals how retinal pigment epithelium morphology adapts to topographical changes without disrupting actin cytoskeleton or polarity, effectively mimicking early ageing before ...
Felix Reul +8 more
wiley +1 more source
Identification of fidelity-determined residues of Porcine reproductive and respiratory syndrome virus through structural alignment. [PDF]
VirulenceGao X +8 more
europepmc +1 more source
Light‐Guided Molecular Patterning for High‐Throughput Single‐Molecule Mechanical Characterization
Small, EarlyView.A light‐guided molecular patterning method is presented for high‐throughput single‐molecule characterization. The approach enables scalable and accessible molecular patterning without specialized lithography equipment. Patterned surfaces are compatible with downstream biophysical assays, demonstrated by magnetic tweezers and flow‐based single‐molecule ...
Hansol Choi, Andrew Ward, Wesley P. Wong
wiley +1 more source
Targeting Genome Maintenance Defects of Cancers Using Chain-Terminating Nucleoside Analogs. [PDF]
Cancer SciKawasumi R, E Tabassum R, Hirota K.
europepmc +1 more source
Phenotypic screening of a focused nucleoside library [PDF]
, 2016 Hulpia, Fabian, Van Calenbergh, Serge
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