Results 101 to 110 of about 1,571 (134)
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Adenosine Deaminase and Purine Nucleoside Phosphorylase Activities during Culturing of Fibrolasts
1980Fibroblast cultures can be used as a valuable model for the study of inborn errors and as an important diagnostic tool, e.g. amniotic fluid derived fibroblasts in prenatal diagnosis (1–3). In order to develop reliable enzyme assays of fibroblasts the effect of cell culture conditions on enzyme activities should be known.
M P, Uitendaal +4 more
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Adenosine Deaminase and Purine Nucleoside Phosphorylase in Acute and Chronic Lymphatic Leukemia
1980Significant progress in the classification of leukemia has been achieved by the introduction of methods which make detailled characterisation of cell membrane antigens or receptors possible (1). These methods have proved to be of considerable clinical relevance as tools for precise classification of the underlying leukemic process, thus providing more ...
H, Ludwig +3 more
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Pediatrics International, 1981
Summary We have established the screening methods for PNP and ADA deficiencies and screened 41 immunodeficient patients since 1976. Two of 8 patients with combined immunodeficiency have been found to have ADA deficiency. They were the first and second cases in Japan. The second case with ADA deficiency, born of a second-cousin marriage, was a
Nobuo Sakura +2 more
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Summary We have established the screening methods for PNP and ADA deficiencies and screened 41 immunodeficient patients since 1976. Two of 8 patients with combined immunodeficiency have been found to have ADA deficiency. They were the first and second cases in Japan. The second case with ADA deficiency, born of a second-cousin marriage, was a
Nobuo Sakura +2 more
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Pathogenic mechanisms in deficiencies of adenosine deaminase and purine nucleoside phosphorylase
1979Inherited deficiencies of the enzymes adenosine deaminase (ADA) (E.C.3.5.4.4) and purine nucleoside phosphorylase (PNP) (E.C.2.4.2.1) recently have been associated with human immunodeficiency disease1,2. There are two puzzling dilemmas to explain in these conditions.
D. A. Carson, J. Kaye, J. E. Seegmiller
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[71] Cytosine nucleoside deaminase from Escherichia coli
1955Publisher Summary This chapter discusses the determination of cytosine nucleoside deaminase from Escherichia coli (E. coli) . Spectrophotometric methods are used in following the activity of this enzyme, since the deamination of the cytosine compounds is accompanied b y a decrease in absorption of 55 % at 282 mμ.
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Specificity of inhibition of adenosine deaminase by trialcohols derived from nucleosides
Journal of Medicinal Chemistry, 1973R R, Rossi, L M, Lerner
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Inhibition of adenosine deaminase by alcohols derived from adenine nucleosides
Biochemistry, 1972L M, Lerner, R R, Rossi
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Base editing of organellar DNA with programmable deaminases
Nature Reviews Molecular Cell Biology, 2023Jia Chen, Jin-Soo Kim
exaly
Nucleoside deaminase activity in viral leukemia.
Cancer research, 1971Rothman, I K, Malathi, V G, Silber, R
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Nucleoside analog studies indicate mechanistic differences between RNA-editing adenosine deaminases
Nucleic Acids Research, 2012Rena Mizrahi, Peter Beal, Beal Peter A
exaly