Results 41 to 50 of about 112 (103)
Luminescence of N2,3‐etheno‐2‐aminopurine Embedded in Polyvinyl Alcohol Films at Room Temperature
The spectral characteristics of N2,3‐etheno‐2‐aminopurine immobilized in poly(vinyl alcohol) films are presented. Direct excitation to the triplet state and the occurrence of room‐temperature phosphorescence were observed. These findings could be useful for developing tools to study biomolecules that are unstable under high‐energy excitation.
Beata Wielgus‐Kutrowska +12 more
wiley +1 more source
ABSTRACT Objective To examine factors influencing breast cancer liver metastases (BCLM) and assess the impact of underlying liver diseases (nonalcoholic fatty liver and HBsAg infection) on BCLM development. Methods Patients diagnosed with breast cancer at four affiliated hospitals in China between 2014 and 2024 were included.
Xiaowen Wang +16 more
wiley +1 more source
Emerging Roles of Adenosine Metabolism in Astrocytes During Brain Injury
Adenosine, as a key metabolic and neurotransmitter in the brain, has become an important therapeutic target for improving the efficacy of immunotherapy for stroke. However, gaps in knowledge about its metabolic pathways have become a key factor limiting its clinical translation.
Shu Zhu +4 more
wiley +1 more source
Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications
The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff +2 more
wiley +1 more source
In silico antimalarial bioprospecting of neem (Azadirachta indica) quinine-derivative alkaloids
Malaria, driven by the protozoan Plasmodium spp. and transmitted by Anopheles mosquitoes, remains a significant global health threat. With the emergence of chloroquine-resistant malaria, alternative treatments derived from natural compounds are pressing.
Alfin Hidayat +4 more
doaj +1 more source
Rationale for the Use of 8‐Aminoguanine for the Management of Cystitis
ABSTRACT Bladder pain and associated lower urinary tract symptoms (LUTSs) are hallmark features of interstitial cystitis/bladder pain syndrome (IC/BPS) and hemorrhagic cystitis (HC). IC/BPS is characterized by bladder‐based pain and irritative bladder symptoms, with or without gross inflammatory changes (Hunner lesions) in the bladder wall, and the ...
Lori A. Birder +3 more
wiley +1 more source
Abstract Background Chronic intestinal pseudo‐obstruction (CIPO) is a severe gastrointestinal motility disorder that may be idiopathic or associated with systemic disease. In idiopathic cases, the pathophysiological mechanisms remain poorly defined. Although mutations in angiogenic factors have been reported in mitochondrial forms of CIPO, their role ...
Elisa Boschetti +17 more
wiley +1 more source
Purine Nucleoside Phosphorylase Deficiency [PDF]
William R. A. Osborne +5 more
openaire +1 more source

