Results 211 to 220 of about 197,362 (384)

Chemoselective Difluoromethylation of Nucleosides. [PDF]

open access: yesOrg Lett
Linden O   +3 more
europepmc   +1 more source

Comprehensive Multi‐Omics Integration Reveals B Cell‐Derived ELL2 as a Novel Diagnostic and Prognostic Biomarker in Sepsis

open access: yesMed Research, EarlyView.
We analyzed bulk transcriptome sequencing data from 10 cohorts of sepsis patients. Using unbiased patient clustering, we identified three subtypes with significantly different prognoses, which were consistently reproduced across all 10 cohorts. Through comprehensive multi‐angle analyses, we revealed distinct differences among the subtypes in terms of ...
Xuan Wang, Jihong Li, Jingyuan Ning
wiley   +1 more source

Quantifying the mRNA epitranscriptome reveals epitranscriptome signatures and roles in cancer. [PDF]

open access: yesCell Mol Life Sci
Feng Y   +11 more
europepmc   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro   +5 more
wiley   +1 more source

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller   +5 more
wiley   +1 more source

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