Results 31 to 40 of about 197,362 (384)
Identification and quantification of modified nucleosides in Saccharomyces cerevisiae mRNAs
bioRxiv, 2018 Post-transcriptional nucleoside modifications have long been recognized as key modulators of non-coding RNA structure and function. There is an emerging appreciation that the chemical modification of protein-coding messenger RNAs (mRNAs) also plays ...
Mehmet Tardu, Q. Lin, Kristin S. Koutmou
semanticscholar +1 more source
Testicular disposition of clofarabine in rats is dependent on equilibrative nucleoside transporters
Pharmacology Research & Perspectives, 2021 Acute lymphoblastic leukemia (ALL) is the most common cancer in children and adolescents. Although the 5‐year survival rate is high, some patients respond poorly to chemotherapy or have recurrence in locations such as the testis. The blood–testis barrier
Siennah R. Miller +7 more
doaj +1 more source
Nucleotides: Structure and Properties [PDF]
, 2005 Nucleotides consist of a nitrogen-containing base, a five-carbon sugar, and one or more phosphate groups. Cells contain many types of nucleotides, which play a central role in a wide variety of cellular processes, including metabolic regulation and the ...
Bowater, RP
core +1 more source
A sequential direct arylation/Suzuki-Miyaura cross-coupling transformation of unprotected 2 '-deoxyadenosine affords a novel class of fluorescent analogues [PDF]
, 2010 Novel rigid 8-biaryl-2'-deoxyadenosines with tuneable fluorescent properties can be accessed by an efficient sequential catalytic Pd-0-coupling ...
Baumann, C.G. +3 more
core +1 more source
Chemical and Conformational Diversity of Modified Nucleosides Affects tRNA Structure and Function
Biomolecules, 2017 RNAs are central to all gene expression through the control of protein synthesis. Four major nucleosides, adenosine, guanosine, cytidine and uridine, compose RNAs and provide sequence variation, but are limited in contributions to structural variation as
Ville Y. P. Väre +4 more
semanticscholar +1 more source
Mycology, 2017 Nucleosides and nucleobases are one of the most important indicators of quality control. A sensitive and reliable high performance liquid chromatography-ultraviolet method was applied to analyse 13 nucleosides and nucleobases simultaneously in 15 batches
Wenming Cheng +6 more
doaj +1 more source
A One-Pot Approach to Novel Pyridazine C-Nucleosides
Molecules, 2021 The synthesis of glycosides and modified nucleosides represents a wide research field in organic chemistry. The classical methodology is based on coupling reactions between a glycosyl donor and an acceptor.
Flavio Cermola +4 more
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Metabolisms of Nucleosides in Bacteria
Agricultural and Biological Chemistry, 1967 Pyrimidine nucleoside phosphorylases obtained from Er. carotovora and Cor. sepedonicum were purified by means of ammonium sulfate fractionation and DEAE-cellulose column chromatography. Some properties of these enzyme were also studied. The enzyme from Cor.
Takuo Sakai +3 more
openalex +7 more sources
Biotransformation of halogenated 2′-deoxyribosides by immobilized lactic acid bacteria [PDF]
, 2012 An efficient and green bioprocess is herein reported to obtain halogenated nucleosides by transglycosylation using immobilized lactic acid bacteria (LAB).
Britos, Claudia Noelia +5 more
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Thermodynamic reaction control of nucleoside phosphorolysis [PDF]
, 2020 Nucleoside analogs represent a class of important drugs for cancer and antiviral treatments. Nucleoside phosphorylases (NPases) catalyze the phosphorolysis of nucleosides and are widely employed for the synthesis of pentose‐1‐phosphates and nucleoside ...
Giessmann, Robert T. +4 more
core +1 more source