Results 261 to 270 of about 141,257 (371)

UV-induced formation of pyrimidine dimers in nucleosome core DNA is strongly modulated with a period of 10.3 bases.

, 1987
James M. Gale, K A Nissen, Michael J. Smerdon   +2 more
openalex   +1 more source

Advances in Isotope Labeling for Solution Nucleic Acid Nuclear Magnetic Resonance Spectroscopy

ChemPlusChem, Volume 90, Issue 7, July 2025.
Recent advances in the field of nucleic acid nuclear magnetic resonance (NMR) are presented. Stable isotope labeling protocols and new approaches to segmentally label nucleic acid with NMR‐active residues are summarized. The novel methods will have a strong impact on the future of nucleic acid NMR and the characterization of structure and dynamics of ...
Stefan Hilber, Solomon Kojo Attionu, Theodore Kwaku Dayie, Christoph Kreutz   +3 more
wiley   +1 more source

Compromised two-start zigzag chromatin folding in immature mouse retina cells driven by irregularly spaced nucleosomes with short DNA linkers. [PDF]

Nucleic Acids Res
Kable B, Portillo-Ledesma S, Popova EY, Jentink N, Swulius M, Li Z, Schlick T, Grigoryev SA.   +7 more
europepmc   +1 more source

Arid1a deficiency sensitises pancreatic cancer to fatty acid synthase inhibition

Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.
Combination of Kras activation and Arid1a loss induces pancreatic cancer in mice. ARID1A deficiency enhances immune cell infiltration and lipid metabolism in pancreatic cancer. Fatty acid synthase (FASN) is a druggable target in ARID1A‐deficient pancreatic cancer.
Tzu‐Lei Kuo, Ya‐Chin Hou, Yan‐Shen Shan, Li‐Tzong Chen, Wen‐Chun Hung   +4 more
wiley   +1 more source

Plasma H3.1 nucleosomes as biomarkers of infection, inflammation and organ failure. [PDF]

Crit Care
Filippini DFL, Jiang M, Kramer L, van der Poll T, Cremer O, Hla TTW, Retter A, Bos LDJ, MARS consortium.   +8 more
europepmc   +1 more source

Nucleosomes inhibit both transcriptional initiation and elongation by RNA polymerase III in vitro.

, 1989
Randall H. Morse
openalex   +1 more source

Immunogenic DNA-related factors. Nucleosomes spontaneously released from normal murine lymphoid cells stimulate proliferation and immunoglobulin synthesis of normal mouse lymphocytes. [PDF]

, 1990
David Bell, B E Morrison, P VandenBygaart   +2 more
openalex   +1 more source

Effects of the Missense Variants on Complete Phenotype and Splicing Variant on Severe Growth Retardation in the BPTF Gene

Developmental Neurobiology, Volume 85, Issue 3, July 2025.
ABSTRACT Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies (NEDDFL, OMIM no #617755) is an ultra‐rare syndrome associated with heterozygous pathogenic variants in the BPTF gene. Haploinsufficiency of the BPTF gene, a chromatin remodeling gene that is related to epigenetic modification, is the cause of this disease.
Gül Ünsel‐Bolat, Hamide Betul Gerik‐Celebi, Betül Diler Durgut, Ayberk Türkyılmaz, Hilmi Bolat   +4 more
wiley   +1 more source

Gene promoters are genomically encoded to facilitate histone exchange/incorporation. [PDF]

PLoS Biol
Bartholomew B.
europepmc   +1 more source

A transcriptionally active tRNA gene interferes with nucleosome positioning in vivo. [PDF]

, 1992
Randall H. Morse, Sharon Y. Roth, R T Simpson   +2 more
openalex   +1 more source